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PACSIN 2 represses cellular migration through direct association with cyclin D1 but not its alternate splice form cyclin D1b

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Pages 73-81 | Published online: 01 Jan 2011

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Guergana Tchakarska & Brigitte Sola. (2020) The double dealing of cyclin D1. Cell Cycle 19:2, pages 163-178.
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Haymar Wint, Jianzhen Li, Tadashi Abe, Hiroshi Yamada, Takumi Higaki, Yasutomo Nasu, Masami Watanabe, Kohji Takei & Tetsuya Takeda. (2023) Pacsin 2-dependent N-cadherin internalization regulates the migration behaviour of malignant cancer cells. Journal of Cell Science 136:10.
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Kibeom Park, Hee‐Seop Yoo, Chang‐Kyu Oh, Joo Rak Lee, Hee Jin Chung, Ha‐Neul Kim, Soo‐Hyun Kim, Kyung‐Mi Kee, Tong Yoon Kim, Myungshin Kim, Byung‐Gyu Kim, Jae Sun Ra, Kyungjae Myung, Hongtae Kim, Seung Hun Han, Min‐Duk Seo, Yoonsung Lee & Dong‐Wook Kim. (2022) Reciprocal interactions among Cobll1, PACSIN2, and SH3BP1 regulate drug resistance in chronic myeloid leukemia. Cancer Medicine 11:21, pages 4005-4020.
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Vincent Dumont & Sanna Lehtonen. (2022) PACSIN proteins in vivo: Roles in development and physiology. Acta Physiologica 234:3.
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Bernardo Bonilauri, Amanda C. Camillo-Andrade, Marlon D. M. Santos, Juliana de S. da G. Fischer, Paulo C. Carvalho & Bruno Dallagiovanna. (2021) Proteogenomic Analysis Reveals Proteins Involved in the First Step of Adipogenesis in Human Adipose-Derived Stem Cells. Stem Cells International 2021, pages 1-14.
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Shalini Jaswal, Vijay Anand, Syed Azmal Ali, Manoj K. Jena, Sudarshan Kumar, Jai K. Kaushik & Ashok K. Mohanty. (2021) TMT based deep proteome analysis of buffalo mammary epithelial cells and identification of novel protein signatures during lactogenic differentiation. The FASEB Journal 35:6.
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Francesca Ida Montalto & Francesca De Amicis. (2020) Cyclin D1 in Cancer: A Molecular Connection for Cell Cycle Control, Adhesion and Invasion in Tumor and Stroma. Cells 9:12, pages 2648.
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Ke Chen, Xuanmao Jiao, Agnese Di Rocco, Duanwen Shen, Shaohua Xu, Adam Ertel, Zuoren Yu, Gabriele Di Sante, Min Wang, Zhiping Li, Timothy G. Pestell, Mathew C. Casimiro, Emmanuel Skordalakes, Samuel Achilefu & Richard G. Pestell. (2020) Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation. Cell Reports 32:11, pages 108151.
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Jiyeon Seo & Mikyoung Park. (2019) Molecular crosstalk between cancer and neurodegenerative diseases. Cellular and Molecular Life Sciences 77:14, pages 2659-2680.
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L. Simón, A. Campos, L. Leyton & A. F. G. Quest. (2020) Caveolin-1 function at the plasma membrane and in intracellular compartments in cancer. Cancer and Metastasis Reviews 39:2, pages 435-453.
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Lap P. Nguyen, Si C. Tran, Shiro Suetsugu, Yun-Sook Lim & Soon B. Hwang. (2020) PACSIN2 Interacts with Nonstructural Protein 5A and Regulates Hepatitis C Virus Assembly. Journal of Virology 94:5.
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Tània Cemeli, Marta Guasch‐Vallés, Mireia Nàger, Isidre Felip, Serafí Cambray, Maria Santacana, Sònia Gatius, Neus Pedraza, Xavier Dolcet, Francisco Ferrezuelo, Alberto J Schuhmacher, Judit Herreros & Eloi Garí. (2019) Cytoplasmic cyclin D1 regulates glioblastoma dissemination. The Journal of Pathology 248:4, pages 501-513.
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Xing’an Zhang, Lanfang Zhang, Xiaoyao Tan, Ying Lin, Xinsheng Han, Huadong Wang, Huawei Ming, Qiujiang Li, Kang Liu & Gang Feng. (2018) Systematic analysis of genes involved in oral cancer metastasis to lymph nodes. Cellular & Molecular Biology Letters 23:1.
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Joseph A. Caruso, Mylinh T. Duong, Jason P. W. Carey, Kelly K. Hunt & Khandan Keyomarsi. (2018) Low-Molecular-Weight Cyclin E in Human Cancer: Cellular Consequences and Opportunities for Targeted Therapies. Cancer Research 78:19, pages 5481-5491.
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Judith Semmler, Jan Kormann, Sureshkumar Perumal Srinivasan, Annette Köster, Daniel Sälzer, Michael Reppel, Jürgen Hescheler, Markus Plomann & Filomain Nguemo. (2018) Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart. Pharmacological Research 128, pages 200-210.
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Gabriele Di Sante, Mathew C. Casimiro, Zhiping Li, Adam Ertel, Peter Tompa & Richard G. Pestell. 2018. D-type Cyclins and Cancer. D-type Cyclins and Cancer 61 90 .
Simon Body, Anna Esteve-Arenys, Hadjer Miloudi, Clara Recasens-Zorzo, Guergana Tchakarska, Alexandra Moros, Sophie Bustany, Anna Vidal-Crespo, Vanina Rodriguez, Régis Lavigne, Emmanuelle Com, Isolda Casanova, Ramón Mangues, Oliver Weigert, Alejandra Sanjuan-Pla, Pablo Menéndez, Bénédicte Marcq, Jean-Michel Picquenot, Patricia Pérez-Galán, Fabrice Jardin, Gaël Roué & Brigitte Sola. (2017) Cytoplasmic cyclin D1 controls the migration and invasiveness of mantle lymphoma cells. Scientific Reports 7:1.
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Gabriele Di Sante, Agnese Di Rocco, Claudia Pupo, Mathew C. Casimiro & Richard G. Pestell. (2017) Hormone-induced DNA damage response and repair mediated by cyclin D1 in breast and prostate cancer. Oncotarget 8:47, pages 81803-81812.
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Adenrele M. Gleason, Ken C. Q. Nguyen, David H. Hall & Barth D. Grant. (2016) Syndapin/SDPN-1 is required for endocytic recycling and endosomal actin association in the Caenorhabditis elegans intestine . Molecular Biology of the Cell 27:23, pages 3746-3756.
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Sophie Bustany, Jérôme Bourgeais, Guergana Tchakarska, Simon Body, Olivier Hérault, Fabrice Gouilleux & Brigitte Sola. (2016) Cyclin D1 unbalances the redox status controlling cell adhesion, migration, and drug resistance in myeloma cells. Oncotarget 7:29, pages 45214-45224.
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Hui Zhang, Tao Liu, Zhen Zhang, Samuel H. Payne, Bai Zhang, Jason E. McDermott, Jian-Ying Zhou, Vladislav A. Petyuk, Li Chen, Debjit Ray, Shisheng Sun, Feng Yang, Lijun Chen, Jing Wang, Punit Shah, Seong Won Cha, Paul Aiyetan, Sunghee Woo, Yuan Tian, Marina A. Gritsenko, Therese R. Clauss, Caitlin Choi, Matthew E. Monroe, Stefani Thomas, Song Nie, Chaochao Wu, Ronald J. Moore, Kun-Hsing Yu, David L. Tabb, David Fenyö, Vineet Bafna, Yue Wang, Henry Rodriguez, Emily S. Boja, Tara Hiltke, Robert C. Rivers, Lori Sokoll, Heng Zhu, Ie-Ming Shih, Leslie Cope, Akhilesh Pandey, Bing Zhang, Michael P. Snyder, Douglas A. Levine, Richard D. Smith, Daniel W. Chan, Karin D. Rodland, Steven A. Carr, Michael A. Gillette, Karl R. Klauser, Eric Kuhn, D.R. Mani, Philipp Mertins, Karen A. Ketchum, Ratna Thangudu, Shuang Cai, Mauricio Oberti, Amanda G. Paulovich, Jeffrey R. Whiteaker, Nathan J. Edwards, Peter B. McGarvey, Subha Madhavan, Pei Wang, Daniel W. Chan, Akhilesh Pandey, Ie-Ming Shih, Hui Zhang, Zhen Zhang, Heng Zhu, Leslie Cope, Gordon A. Whiteley, Steven J. Skates, Forest M. White, Douglas A. Levine, Emily S. Boja, Christopher R. Kinsinger, Tara Hiltke, Mehdi Mesri, Robert C. Rivers, Henry Rodriguez, Kenna M. Shaw, Stephen E. Stein, David Fenyo, Tao Liu, Jason E. McDermott, Samuel H. Payne, Karin D. Rodland, Richard D. Smith, Paul Rudnick, Michael Snyder, Yingming Zhao, Xian Chen, David F. Ransohoff, Andrew N. Hoofnagle, Daniel C. Liebler, Melinda E. Sanders, Zhiao Shi, Robbert J.C. Slebos, David L. Tabb, Bing Zhang, Lisa J. Zimmerman, Yue Wang, Sherri R. Davies, Li Ding, Matthew J.C. Ellis & R. Reid Townsend. (2016) Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer. Cell 166:3, pages 755-765.
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Noel P. Fusté, Rita Fernández-Hernández, Tània Cemeli, Cristina Mirantes, Neus Pedraza, Marta Rafel, Jordi Torres-Rosell, Neus Colomina, Francisco Ferrezuelo, Xavier Dolcet & Eloi Garí. (2016) Cytoplasmic cyclin D1 regulates cell invasion and metastasis through the phosphorylation of paxillin. Nature Communications 7:1.
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Noel P. Fusté, Esmeralda Castelblanco, Isidre Felip, Maria Santacana, Rita Fernández-Hernández, Sònia Gatius, Neus Pedraza, Judit Pallarés, Tània Cemeli, Joan Valls, Marc Tarres, Francisco Ferrezuelo, Xavier Dolcet, Xavier Matias-Guiu & Eloi Garí. (2016) Characterization of cytoplasmic cyclin D1 as a marker of invasiveness in cancer. Oncotarget 7:19, pages 26979-26991.
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Francesco Marampon, Giovanni Gravina, Xiaoming Ju, Antonella Vetuschi, Roberta Sferra, Mathew C. Casimiro, Simona Pompili, Claudio Festuccia, Alessandro Colapietro, Eugenio Gaudio, Ernesto Di Cesare, Vincenzo Tombolini & Richard G. Pestell. (2015) Cyclin D1 silencing suppresses tumorigenicity, impairs DNA double strand break repair and thus radiosensitizes androgen-independent prostate cancer cells to DNA damage. Oncotarget 7:5, pages 5383-5400.
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Gabriele Di Sante, Liping Wang, Chenguang Wang, Xuanmiao Jiao, Mathew C. Casimiro, Ke Chen, Timothy G. Pestell, Ismail Yaman, Agnese Di Rocco, Xin Sun, Yoshiyuki Horio, Michael J. Powell, Xiaohong He, Michael W. McBurney & Richard G. Pestell. (2015) Sirt1-Deficient Mice Have Hypogonadotropic Hypogonadism due to Defective GnRH Neuronal Migration. Molecular Endocrinology 29:2, pages 200-212.
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G. Yao, X. Su, V. Nguyen, K. Roberts, X. Li, A. Takakura, M. Plomann & J. Zhou. (2014) Polycystin-1 regulates actin cytoskeleton organization and directional cell migration through a novel PC1-Pacsin 2-N-Wasp complex. Human Molecular Genetics 23:10, pages 2769-2779.
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Yong Fang, Zipeng Cao, Qi Hou, Chen Ma, Chunsuo Yao, Jingxia Li, Xue-Ru Wu & Chuanshu Huang. (2013) Cyclin D1 Downregulation Contributes to Anticancer Effect of Isorhapontigenin on Human Bladder Cancer Cells. Molecular Cancer Therapeutics 12:8, pages 1492-1503.
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Richard G. Pestell. (2013) New Roles of Cyclin D1. The American Journal of Pathology 183:1, pages 3-9.
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Gang Yao, Annouck Luyten, Ayumi Takakura, Markus Plomann & Jing Zhou. (2013) The cytoplasmic protein Pacsin 2 in kidney development and injury repair. Kidney International 83:3, pages 426-437.
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Chenguang Wang, Timothy G. Pestell & Richard G. Pestell. 2013. Cell and Molecular Biology of Breast Cancer. Cell and Molecular Biology of Breast Cancer 289 304 .
Gabriele Stocco, Wenjian Yang, Kristine R. Crews, William E. Thierfelder, Giuliana Decorti, Margherita Londero, Raffaella Franca, Marco Rabusin, Maria Grazia Valsecchi, Deqing Pei, Cheng Cheng, Steven W. Paugh, Laura B. Ramsey, Barthelemy Diouf, Joseph Robert McCorkle, Terreia S. Jones, Ching-Hon Pui, Mary V. Relling & William E. Evans. (2012) PACSIN2 polymorphism influences TPMT activity and mercaptopurine-related gastrointestinal toxicity. Human Molecular Genetics 21:21, pages 4793-4804.
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