Citations (49)
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Sanjay Varikuti, Steve Oghumu, Mohamad Elbaz, Greta Volpedo, Dinesh K. Ahirwar, Pablo C. Alarcon, Rachel H. Sperling, Ellen Moretti, Marissa S. Pioso, Jennifer Kimble, Mohd W. Nasser, Ramesh K. Ganju, Cesar Terrazas & Abhay R. Satoskar. (2017) STAT1 gene deficient mice develop accelerated breast cancer growth and metastasis which is reduced by IL-17 blockade. OncoImmunology 6:11.
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Shuo Wang & Antonis E. Koromilas. (2016) STAT1-mediated translational control in tumor suppression and antitumor therapies. Molecular & Cellular Oncology 3:3.
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Alessandra Pincini, Giusy Tornillo, Francesca Orso, Marianna Sciortino, Brigitte Bisaro, Maria del Pilar Camacho Leal, Antonio Lembo, Maria Felice Brizzi, Emilia Turco, Cristiano De Pittà, Paolo Provero, Enzo Medico, Paola Defilippi, Daniela Taverna & Sara Cabodi. (2013) Identification of p130Cas/ErbB2-dependent invasive signatures in transformed mammary epithelial cells. Cell Cycle 12:15, pages 2409-2422.
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Antonis E. Koromilas & Veronika Sexl. (2013) The tumor suppressor function of STAT1 in breast cancer. JAK-STAT 2:2.
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William H. Chappell, Stephen L. Abrams, Richard A. Franklin, Michelle M. LaHair, Giuseppe Montalto, Melchiorre Cervello, Alberto M. Martelli, Ferdinando Nicoletti, Saverio Candido, Massimo Libra, Jerry Polesel, Renato Talamini, Michele Milella, Agostino Tafuri, Linda S. Steelman & James A. McCubrey. (2012) Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the plant natural product berberine. Cell Cycle 11:23, pages 4447-4461.
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Gloria Bonuccelli, Remedios Castello-Cros, Franco Capozza, Ubaldo E. Martinez-Outschoorn, Zhao Lin, Aristotelis Tsirigos, Jiao Xuanmao, Diana Whitaker-Menezes, Anthony Howell, Michael P. Lisanti & Federica Sotgia. (2012) The milk protein α-casein functions as a tumor suppressor via activation of STAT1 signaling, effectively preventing breast cancer tumor growth and metastasis. Cell Cycle 11:21, pages 3972-3982.
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Sarah G. Bailey, Mark S. Cragg & Paul A. Townsend. (2012) Role of STAT1 in the breast. JAK-STAT 1:3, pages 197-199.
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Katherine Hughes & Christine J. Watson. (2012) The spectrum of STAT functions in mammary gland development. JAK-STAT 1:3, pages 151-158.
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Lidia Avalle, Sara Pensa, Gabriella Regis, Francesco Novelli & Valeria Poli. (2012) STAT1 and STAT3 in tumorigenesis. JAK-STAT 1:2, pages 65-72.
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Articles from other publishers (40)
Annabel T. Olson, Yuqi Kang, Anushka M. Ladha, Songli Zhu, Chuan Bian Lim, Behnam Nabet, Michael Lagunoff, Taranjit S. Gujral & Adam P. Geballe. (2023) Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation. PLOS Pathogens 19:9, pages e1011169.
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Niloofar Deravi & Nima Rezaei. 2023.
Grace L. Wong, Sara G. Manore, Daniel L. Doheny & Hui-Wen Lo. (2022) STAT family of transcription factors in breast cancer: Pathogenesis and therapeutic opportunities and challenges. Seminars in Cancer Biology 86, pages 84-106.
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Xiaokai Ding, Amanda C. Sharko, Martina S. J. McDermott, Gary P. Schools, Alexander Chumanevich, Hao Ji, Jing Li, Li Zhang, Zachary T. Mack, Vitali Sikirzhytski, Michael Shtutman, Laura Ivers, Norma O’Donovan, John Crown, Balázs Győrffy, Mengqian Chen, Igor B. Roninson & Eugenia V. Broude. (2022) Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo. Proceedings of the National Academy of Sciences 119:32.
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Wenying Shu, Xue Zhu, Ke Wang, Svetlana Cherepanoff, R. Max Conway, Michele C. Madigan, Hong Zhu, Ling Zhu, Michael Murray & Fanfan Zhou. (2022) The multi-kinase inhibitor afatinib serves as a novel candidate for the treatment of human uveal melanoma. Cellular Oncology 45:4, pages 601-619.
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Mohsen Sheykhhasan, Naser Kalhor, Azar Sheikholeslami, Masoumeh Dolati, Elaheh Amini & Hoda Fazaeli. (2021) Exosomes of Mesenchymal Stem Cells as a Proper Vehicle for Transfecting miR-145 into the Breast Cancer Cell Line and Its Effect on Metastasis. BioMed Research International 2021, pages 1-15.
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Ling-Wei Hii, Felicia Fei-Lei Chung, Chun Wai Mai, Zong Yang Yee, Hong Hao Chan, Vijay Joseph Raja, Noah Elias Dephoure, Nigel J. Pyne, Susan Pyne & Chee-Onn Leong. (2020) Sphingosine Kinase 1 Regulates the Survival of Breast Cancer Stem Cells and Non-stem Breast Cancer Cells by Suppression of STAT1. Cells 9:4, pages 886.
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Qian Xin, Guanghui Cheng, Feng Kong, Qinghong Ji, Haizhen Li, Wen Jiang, Jue Wang, Yun Luan, Chao Sun, Xiaojing Chen, Xuexiang Wang, Tonggang Qi, Dawei Xu, Lei Song & Qiji Liu. (2020) STAT1 transcriptionally regulates the expression of S1PR1 by binding its promoter region. Gene 736, pages 144417.
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Jianhui Xu, Yang Zhang, Yuxuan Shi, Dongming Yin, Peidong Dai, Weidong Zhao & Tianyu Zhang. (2019) Identification of Predictive Proteins and Biological Pathways for the Tumorigenicity of Vestibular Schwannoma by Proteomic Profiling. PROTEOMICS – Clinical Applications 13:5.
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Edit PorpaczySabrina TripoltAndrea Hoelbl-KovacicBettina GisslingerZsuzsanna Bago-HorvathEmilio Casanova-HeviaEmmanuelle ClappierThomas DeckerSabine FajmannDaniela A. FuxGeorg GreinerSinan GueltekinGerwin HellerHarald Herkner, Gregor HoermannJean-Jacques KiladjianThomas KolbeChristoph KornauthMaria-Theresa KrauthRobert KralovicsLeonhard MuellauerMathias Mueller, Michaela Prchal-MurphyEva Maria PutzEmmanuel Raffoux, Ana-Iris SchieferKlaus SchmettererChristine SchneckenleithnerIngrid Simonitsch-KluppCathrin SkrabsWolfgang R. SperrPhilipp Bernhard StaberBirgit Strobl, Peter ValentUlrich JaegerHeinz GisslingerVeronika Sexl. (2018) Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy. Blood 132:7, pages 694-706.
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Ilija Crnčec, Madhura Modak, Claire Gordziel, Jasmin Svinka, Irene Scharf, Stefan Moritsch, Paulina Pathria, Michaela Schlederer, Lukas Kenner, Gerald Timelthaler, Mathias Müller, Birgit Strobl, Emilio Casanova, Editha Bayer, Thomas Mohr, Johannes Stöckl, Karlheinz Friedrich & Robert Eferl. (2018) STAT1 is a sex-specific tumor suppressor in colitis-associated colorectal cancer. Molecular Oncology 12:4, pages 514-528.
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Hidetoshi Mori, Robert D. Cardiff & Alexander D. Borowsky. (2018) Aging Mouse Models Reveal Complex Tumor-Microenvironment Interactions in Cancer Progression. Frontiers in Cell and Developmental Biology 6.
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Hui Guo, Shan Kuang, Qiao-ling Song, Man Liu, Xiao-xiao Sun & Qiang Yu. (2017) Cucurbitacin I inhibits STAT3, but enhances STAT1 signaling in human cancer cells in vitro through disrupting actin filaments. Acta Pharmacologica Sinica 39:3, pages 425-437.
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Hidetoshi Mori, Jane Q. Chen, Robert D. Cardiff, Zsófia Pénzváltó, Neil E. Hubbard, Louis Schuetter, Russell C. Hovey, Josephine F. Trott & Alexander D. Borowsky. (2017) Pathobiology of the 129:Stat1 −/− mouse model of human age-related ER-positive breast cancer with an immune infiltrate-excluded phenotype. Breast Cancer Research 19:1.
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Kuijie Liu, Hongliang Yao, Sanlin Lei, Li Xiong, Haizhi Qi, Ke Qian, Jiqiang Liu, Peng Wang & Hua Zhao. (2017) The miR-124-p63 feedback loop modulates colorectal cancer growth. Oncotarget 8:17, pages 29101-29115.
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Ryuhjin Ahn, Valérie Sabourin, Alicia M. Bolt, Steven Hébert, Stephanie Totten, Nicolas De Jay, Maria Carolina Festa, Yoon Kow Young, Young Kyuen Im, Tony Pawson, Antonis E. Koromilas, William J. Muller, Koren K. Mann, Claudia L. Kleinman & Josie Ursini-Siegel. (2017) The Shc1 adaptor simultaneously balances Stat1 and Stat3 activity to promote breast cancer immune suppression. Nature Communications 8:1.
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Katrin Meissl, Sabine Macho-Maschler, Mathias Müller & Birgit Strobl. (2017) The good and the bad faces of STAT1 in solid tumours. Cytokine 89, pages 12-20.
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Shuo Wang, Cedric Darini, Laurent Désaubry & Antonis E. Koromilas. (2016)
STAT1 Promotes
KRAS
Colon Tumor Growth and Susceptibility to Pharmacological Inhibition of Translation Initiation Factor eIF4A
. Molecular Cancer Therapeutics 15:12, pages 3055-3063.
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Jane Q. Chen, Hidetoshi Mori, Robert D. Cardiff, Josephine F. Trott, Russell C. Hovey, Neil E. Hubbard, Jesse A. Engelberg, Clifford G. Tepper, Brandon J. Willis, Imran H. Khan, Resmi K. Ravindran, Szeman R. Chan, Robert D. Schreiber & Alexander D. Borowsky. (2015) Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent. PLOS ONE 10:6, pages e0129895.
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Shuo WangChristos Patsis & Antonis E. Koromilas. (2015) Stat1 stimulates cap-independent mRNA translation to inhibit cell proliferation and promote survival in response to antitumor drugs. Proceedings of the National Academy of Sciences 112:17.
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M Koti, A Siu, I Clément, M Bidarimath, G Turashvili, A Edwards, K Rahimi, A-M M Masson & J A Squire. (2015) A distinct pre-existing inflammatory tumour microenvironment is associated with chemotherapy resistance in high-grade serous epithelial ovarian cancer. British Journal of Cancer 112:7, pages 1215-1222.
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James A. McCubrey, Stephen L. Abrams, Timothy L. Fitzgerald, Lucio Cocco, Alberto M. Martelli, Giuseppe Montalto, Melchiorre Cervello, Aurora Scalisi, Saverio Candido, Massimo Libra & Linda S. Steelman. (2015) Roles of signaling pathways in drug resistance, cancer initiating cells and cancer progression and metastasis. Advances in Biological Regulation 57, pages 75-101.
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Piotr Tymoszuk, Pornpimol Charoentong, Hubert Hackl, Rita Spilka, Elisabeth Müller-Holzner, Zlatko Trajanoski, Peter Obrist, Françoise Revillion, Jean-Philippe Peyrat, Heidi Fiegl & Wolfgang Doppler. (2014) High STAT1 mRNA levels but not its tyrosine phosphorylation are associated with macrophage infiltration and bad prognosis in breast cancer. BMC Cancer 14:1.
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A. Dittrich, H. Gautrey, D. Browell & A. Tyson-Capper. (2014) The HER2 Signaling Network in Breast Cancer—Like a Spider in its Web. Journal of Mammary Gland Biology and Neoplasia 19:3-4, pages 253-270.
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Budiman Kharma, Tsukasa Baba, Noriomi Matsumura, Hyun Sook Kang, Junzo Hamanishi, Ryusuke Murakami, Melissa M. McConechy, Samuel Leung, Ken Yamaguchi, Yuko Hosoe, Yumiko Yoshioka, Susan K. Murphy, Masaki Mandai, David G. Hunstman & Ikuo Konishi. (2014) STAT1 Drives Tumor Progression in Serous Papillary Endometrial Cancer. Cancer Research 74:22, pages 6519-6530.
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James A. McCubrey, Nicole M. Davis, Stephen L. Abrams, Giuseppe Montalto, Melchiorre Cervello, Massimo Libra, Ferdinando Nicoletti, Antonino B. D'Assoro, Lucio Cocco, Alberto M. Martelli & Linda S. Steelman. (2014) Targeting breast cancer initiating cells: Advances in breast cancer research and therapy. Advances in Biological Regulation 56, pages 81-107.
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Nicole M. Davis, Melissa Sokolosky, Kristin Stadelman, Stephen L. Abrams, Massimo Libra, Saverio Candido, Ferdinando Nicoletti, Jerry Polesel, Roberta Maestro, Antonino D’Assoro, Lyudmyla Drobot, Dariusz Rakus, Agnieszka Gizak, Piotr Laidler, Joanna Dulińska-Litewka, Joerg Basecke, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Giuseppe Montalto, Melchiorre Cervello, Timothy L. Fitzgerald, Zoya N. Demidenko, Alberto M. Martelli, Lucio Cocco, Linda S. Steelman & James A. McCubrey. (2014) Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention. Oncotarget 5:13, pages 4603-4650.
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Sebak Datta, Nirmala Parajuli, Piotr Tymoszuk, Eleonora Ottina, Walther Parson, Roswitha Sgonc, Andreas Villunger & Wolfgang Doppler. (2014) Replenishment of the B cell compartment after doxorubicin-induced hematopoietic toxicity is facilitated by STAT1. Journal of Leukocyte Biology 95:6, pages 853-866.
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S R Chan, C G Rickert, W Vermi, K C F Sheehan, C Arthur, J A Allen, J M White, J Archambault, S Lonardi, T M McDevitt, D Bhattacharya, M V Lorenzi, D C Allred & R D Schreiber. (2013) Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα+ tumorigenesis. Cell Death & Differentiation 21:2, pages 234-246.
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Nicole R. Leitner, Caroline Lassnig, Rita Rom, Susanne Heider, Zsuzsanna Bago-Horvath, Robert Eferl, Simone Müller, Thomas Kolbe, Lukas Kenner, Thomas Rülicke, Birgit Strobl & Mathias Müller. (2014) Inducible, Dose-Adjustable and Time-Restricted Reconstitution of Stat1 Deficiency In Vivo. PLoS ONE 9:1, pages e86608.
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S. Haricharan & Y. Li. (2014) STAT signaling in mammary gland differentiation, cell survival and tumorigenesis. Molecular and Cellular Endocrinology 382:1, pages 560-569.
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WARAPORN MALILAS, SANG SEOK KOH, SEOKHO KIM, RATAKORN SRISUTTEE, IL-RAE CHO, JEONG MOON, HWA-SEUNG YOO, SANGTAEK OH, RANDAL N. JOHNSTON & YOUNG-HWA CHUNG. (2013) Cancer upregulated gene 2, a novel oncogene, enhances migration and drug resistance of colon cancer cells via STAT1 activation. International Journal of Oncology 43:4, pages 1111-1116.
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Damya Laoui, Eva Van Overmeire & Jo A. Van Ginderachter. (2013) Unsuspected allies: Chemotherapy teams up with immunity to fight cancer. European Journal of Immunology 43:10, pages 2538-2542.
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Lára Hannesdóttir, Piotr Tymoszuk, Nirmala Parajuli, Marie-Helene Wasmer, Sonja Philipp, Nina Daschil, Sebak Datta, Johann-Benedikt Koller, Christoph H. Tripp, Patrizia Stoitzner, Elisabeth Müller-Holzner, Gerrit Jan Wiegers, Veronika Sexl, Andreas Villunger & Wolfgang Doppler. (2013) Lapatinib and doxorubicin enhance the Stat1-dependent antitumor immune response. European Journal of Immunology 43:10, pages 2718-2729.
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Haitao JuXin LiHong Li, Xiaojuan Wang, Hongwei Wang, Yang LiChangwu Dou & Gang Zhao. (2013) Mediation of multiple pathways regulating cell proliferation, migration, and apoptosis in the human malignant glioma cell line U87MG via unphosphorylated STAT1. Journal of Neurosurgery 118:6, pages 1239-1247.
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Mélanie LaurinJennifer HuberAriane PelletierTarek HouallaMorag ParkYoshinori FukuiBenjamin Haibe-Kains, William J. MullerJean-François Côté. (2013) Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis. Proceedings of the National Academy of Sciences 110:18, pages 7434-7439.
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Hua Pan, Jacob W. Myerson, Lingzhi Hu, Jon N. Marsh, Kirk Hou, Michael J. Scott, John S. Allen, Grace Hu, Susana San Roman, Gregory M. Lanza, Robert D. Schreiber, Paul H. Schlesinger & Samuel A. Wickline. (2012)
Programmable nanoparticle functionalization for
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James A. McCubrey, Linda S. Steelman, William H. Chappell, Stephen L. Abrams, Richard A. Franklin, Giuseppe Montalto, Melchiorre Cervello, Massimo Libra, Saverio Candido, Grazia Malaponte, Maria C. Mazzarino, Paolo Fagone, Ferdinando Nicoletti, Jörg Bäsecke, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Michele Milella, Agostino Tafuri, Francesca Chiarini, Camilla Evangelisti, Lucio Cocco & Alberto M. Martelli. (2012) Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance. Oncotarget 3:10, pages 1068-1111.
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Szeman Ruby Chan, William Vermi, Jingqin Luo, Laura Lucini, Charles Rickert, Amy M Fowler, Silvia Lonardi, Cora Arthur, Larry JT Young, David E Levy, Michael J Welch, Robert D Cardiff & Robert D Schreiber. (2012) STAT1-deficient mice spontaneously develop estrogen receptor α-positive luminal mammary carcinomas. Breast Cancer Research 14:1.
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Christine Schneckenleithner, Zsuzsanna Bago-Horvath, Helmut Dolznig, Nina Neugebauer, Karoline Kollmann, Thomas Kolbe, Thomas Decker, Dontscho Kerjaschki, Kay-Uwe Wagner, Mathias Müller, Dagmar Stoiber & Veronika Sexl. (2011) Putting the brakes on mammary tumorigenesis: Loss of STAT1 predisposes to intraepithelial neoplasias. Oncotarget 2:12, pages 1043-1054.
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