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Letter to the Editor

Level of cdk5 expression predicts the survival of relapsed multiple myeloma patients

, &
Pages 4093-4095 | Received 30 Jul 2012, Accepted 20 Aug 2012, Published online: 17 Sep 2012

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Articles from other publishers (29)

Kumar Nikhil & Kavita Shah. (2023) CDK5: an oncogene or an anti-oncogene: location location location. Molecular Cancer 22:1.
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Mitra Zabihi, Ramin Lotfi, Amir-Mohammad Yousefi & Davood Bashash. (2022) Cyclins and cyclin-dependent kinases: from biology to tumorigenesis and therapeutic opportunities. Journal of Cancer Research and Clinical Oncology 149:4, pages 1585-1606.
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Miriana Di Stefano, Salvatore Galati, Gabriella Ortore, Isabella Caligiuri, Flavio Rizzolio, Costanza Ceni, Simone Bertini, Giulia Bononi, Carlotta Granchi, Marco Macchia, Giulio Poli & Tiziano Tuccinardi. (2022) Machine Learning-Based Virtual Screening for the Identification of Cdk5 Inhibitors. International Journal of Molecular Sciences 23:18, pages 10653.
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Shridhar Veeresh Pattar, Shakeel Ahamed Adhoni, Chandrappa Mukappa Kamanavalli & Suresh Sadashiv Kumbar. (2020) In silico molecular docking studies and MM/GBSA analysis of coumarin-carbonodithioate hybrid derivatives divulge the anticancer potential against breast cancer. Beni-Suef University Journal of Basic and Applied Sciences 9:1.
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Brilliant N. Marak, Jayanta Dowarah, Laldingluaia Khiangte & Ved Prakash Singh. (2020) A comprehensive insight on the recent development of Cyclic Dependent Kinase inhibitors as anticancer agents. European Journal of Medicinal Chemistry 203, pages 112571.
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Jordan L Kohlmeyer, David J Gordon, Munir R Tanas, Varun Monga, Rebecca D Dodd & Dawn E Quelle. (2020) CDKs in Sarcoma: Mediators of Disease and Emerging Therapeutic Targets. International Journal of Molecular Sciences 21:8, pages 3018.
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Hailong Tang, Li Xu, Xi Cen, Li Yang, Juan Feng, Guang Li, Huafeng Zhu, Shan Gao, Yan Yu, Yaping Zhao, Zhiqiang Tian, Liping Hou, Shuchun Yu & Guangxun Gao. (2020) CDK5 inhibition in�vitro and in vivo induces cell death in�myeloma and overcomes the obstacle of bortezomib resistance. International Journal of Molecular Medicine.
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Samanta Sharma & Piotr Sicinski. (2020) A kinase of many talents: non-neuronal functions of CDK5 in development and disease. Open Biology 10:1, pages 190287.
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Chia-Yi Su, Ruei-Liang Yan, Wen-Hsin Hsu, Ching-Tung Chu, Hsuan-Chia Chang, Chien-Chen Lai, Hui-Ping Hsu & Hong-Chen Chen. (2019) Phosphorylation of adducin-1 by cyclin-dependent kinase 5 is important for epidermal growth factor-induced cell migration. Scientific Reports 9:1.
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Yun Dai, Fengyan Jin, Wei Wu & Shaji K. Kumar. (2019) Cell cycle regulation and hematologic malignancies. Blood Science 1:1, pages 34-43.
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Elena Kapora, Shujun Feng, Wei Liu, Indira Sakhautdinova, Bo Gao & Wenhua Tan. (2019) MicroRNA-505-5p functions as a tumor suppressor by targeting cyclin-dependent kinase 5 in cervical cancer. Bioscience Reports 39:7.
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Magdalena Bachmann, Roberto Costa, Roberta Peruzzo, Elena Prosdocimi, Vanessa Checchetto & Luigi Leanza. (2018) Targeting Mitochondrial Ion Channels to Fight Cancer. International Journal of Molecular Sciences 19:7, pages 2060.
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Saranya NavaneethaKrishnan, Jesusa L. Rosales & Ki-Young Lee. (2018) Loss of Cdk5 in breast cancer cells promotes ROS-mediated cell death through dysregulation of the mitochondrial permeability transition pore. Oncogene 37:13, pages 1788-1804.
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Jimma Likisa Lenjisa, Solomon Tadesse, Nishat Zareen Khair, Malika Kumarasiri, Mingfeng Yu, Hugo Albrecht, Robert Milne & Shudong Wang. (2017) CDK5 in oncology: recent advances and future prospects. Future Medicinal Chemistry 9:16, pages 1939-1962.
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Floriana Maria Farina, Alessandra Inguscio, Paolo Kunderfranco, Alice Cortesi, Leonardo Elia & Manuela Quintavalle. (2017) MicroRNA-26a/cyclin-dependent kinase 5 axis controls proliferation, apoptosis and in vivo tumor growth of diffuse large B-cell lymphoma cell lines. Cell Death & Disease 8:6, pages e2890-e2890.
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Linlin Ding, Yaodong Shen, Jing Ni, Yiqing Ou, Yangyu Ou & Hong Liu. (2017) EphA4 promotes cell proliferation and cell adhesion–mediated drug resistance via the AKT pathway in multiple myeloma. Tumor Biology 39:3, pages 101042831769429.
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Hanley N. Abramson. (2016) Kinase inhibitors as potential agents in the treatment of multiple myeloma. Oncotarget 7:49, pages 81926-81968.
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Pao-Hsuan Huang, Mei-Chih Chen, Yu-Ting Peng, Wei-Hsiang Kao, Chih-Hsiang Chang, Yun-Chi Wang, Chih-Ho Lai, Jer-Tsong Hsieh, Jo-Hsin Wang, Yueh-Tsung Lee, Eugene Lin, Chia-Herng Yue, Hsin-Yi Wang, Shuen-Chi You & Ho Lin. (2016) Cdk5 Directly Targets Nuclear p21CIP1 and Promotes Cancer Cell Growth. Cancer Research 76:23, pages 6888-6900.
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Karine Pozo & James A. Bibb. (2016) The Emerging Role of Cdk5 in Cancer. Trends in Cancer 2:10, pages 606-618.
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Jahangir Abdi, Hou Jian & Hong Chang. (2016) Role of micro-RNAs in drug resistance of multiple myeloma. Oncotarget 7:37, pages 60723-60735.
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Robert RoskoskiJr.Jr.. (2016) Cyclin-dependent protein kinase inhibitors including palbociclib as anticancer drugs. Pharmacological Research 107, pages 249-275.
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Kanglai Wei, Zhihua Ye, Zuyun Li, Yiwu Dang, Xin Chen, Na Huang, Chongxi Bao, Tingqing Gan, Lihua Yang & Gang Chen. (2016) An immunohistochemical study of cyclin-dependent kinase 5 (CDK5) expression in non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC): a possible prognostic biomarker. World Journal of Surgical Oncology 14:1.
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Ruan Yushan, Chen Wenjie, Huang Suning, Dang Yiwu, Zhong Tengfei, Wickramaarachchi Mihiranganee Madushi, Luo Feifei, Zhang Changwen, Wen Xin, Gopaul Roodrajeetsing, Li Zuyun & Chen Gang. (2015) Insights into the clinical value of cyclin-dependent kinase 5 in glioma: a retrospective study. World Journal of Surgical Oncology 13:1.
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Savita Bisht, Jens Nolting, Ute Schütte, Jens Haarmann, Prashi Jain, Dhruv Shah, Peter Brossart, Patrick Flaherty & Georg Feldmann. (2015) Cyclin-Dependent Kinase 5 (CDK5) Controls Melanoma Cell Motility, Invasiveness, and Metastatic Spread—Identification of a Promising Novel therapeutic target. Translational Oncology 8:4, pages 295-307.
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Shu Zhang, Zhen Lu, Weiqun Mao, Ahmed A. Ahmed, Hailing Yang, Jinhua Zhou, Nicholas Jennings, Cristian Rodriguez-Aguayo, Gabriel Lopez-Berestein, Roberto Miranda, Wei Qiao, Veera Baladandayuthapani, Zongfang Li, Anil K. Sood, Jinsong Liu, Xiao-Feng Le & Robert C. Bast. (2015) CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis. PLOS ONE 10:7, pages e0131833.
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Julia Lindqvist, Susumu Y. Imanishi, Elin Torvaldson, Marjo Malinen, Mika Remes, Fanny Örn, Jorma J. Palvimo & John E. Eriksson. (2015) Cyclin-dependent kinase 5 acts as a critical determinant of AKT-dependent proliferation and regulates differential gene expression by the androgen receptor in prostate cancer cells. Molecular Biology of the Cell 26:11, pages 1971-1984.
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Marion Peyressatre, Camille Prével, Morgan Pellerano & May Morris. (2015) Targeting Cyclin-Dependent Kinases in Human Cancers: From Small Molecules to Peptide Inhibitors. Cancers 7:1, pages 179-237.
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Brajendra K. Tripathi, Xiaolan Qian, Philipp Mertins, Dunrui Wang, Alex G. Papageorge, Steven A. Carr & Douglas R. Lowy. (2014) CDK5 is a major regulator of the tumor suppressor DLC1. Journal of Cell Biology 207:5, pages 627-642.
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Camille Prével, Laetitia Kurzawa, Thi Nhu Ngoc Van & May C. Morris. (2014) Fluorescent biosensors for drug discovery new tools for old targets – Screening for inhibitors of cyclin-dependent kinases. European Journal of Medicinal Chemistry 88, pages 74-88.
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