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Depletion of Aurora A leads to upregulation of FoxO1 to induce cell cycle arrest in hepatocellular carcinoma cells

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Pages 67-75 | Published online: 19 Dec 2012

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Chengfu Yuan, Lei Wang, Liang Zhou & Zheng Fu. (2014) The function of FOXO1 in the late phases of the cell cycle is suppressed by PLK1-mediated phosphorylation. Cell Cycle 13:5, pages 807-819.
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Articles from other publishers (28)

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Takahiro Kodama, Michiko Kodama, Nancy A. Jenkins, Neal G. Copeland, Huanhuan Joyce Chen & Zhubo Wei. (2022) Ring Finger Protein 125 Is an Anti-Proliferative Tumor Suppressor in Hepatocellular Carcinoma. Cancers 14:11, pages 2589.
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Jian Wan, Shunfang Liu, Wanju Sun, Haiyi Yu, Wenlian Tang, Wei Liu, Jing Ji & Bin Liu. (2021) Ring finger protein 152-dependent degradation of TSPAN12 suppresses hepatocellular carcinoma progression. Cancer Cell International 21:1.
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Shaojie Yang, Liwei Pang, Wanlin Dai, Shuodong Wu, Tengqi Ren, Yunlong Duan, Yuting Zheng, Shiyuan Bi, Xiaolin Zhang & Jing Kong. (2021) Role of Forkhead Box O Proteins in Hepatocellular Carcinoma Biology and Progression (Review). Frontiers in Oncology 11.
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Zahra Musavizadeh, Alessandro Grottesi, Giulia Guarguaglini & Alessandro Paiardini. (2021) Phosphorylation, Mg-ADP, and Inhibitors Differentially Shape the Conformational Dynamics of the A-Loop of Aurora-A. Biomolecules 11:4, pages 567.
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Yannasittha Jiramongkol & Eric W.-F. Lam. (2020) FOXO transcription factor family in cancer and metastasis. Cancer and Metastasis Reviews 39:3, pages 681-709.
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Zhongqin Gong, Jianqing Yu, Shucai Yang, Paul B.S. Lai & George G. Chen. (2020) FOX transcription factor family in hepatocellular carcinoma. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1874:1, pages 188376.
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Johannes Ommer, Joanna L. Selfe, Marco Wachtel, Eleanor M. O'Brien, Dominik Laubscher, Michaela Roemmele, Stephanie Kasper, Olivier Delattre, Didier Surdez, Gemma Petts, Anna Kelsey, Janet Shipley & Beat W. Schäfer. (2020) Aurora A Kinase Inhibition Destabilizes PAX3-FOXO1 and MYCN and Synergizes with Navitoclax to Induce Rhabdomyosarcoma Cell Death. Cancer Research 80:4, pages 832-842.
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Jiangdong An, Guangjie Li, Jin Zhang, Haiyu Zhou, Jin Jiang, Xingwen Wang, Xiaofei Feng & Shuanke Wang. (2019) GNAS knockdown suppresses osteogenic differentiation of mesenchymal stem cells via activation of Hippo signaling pathway. Journal of Cellular Physiology 234:12, pages 22299-22310.
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Shuai Wang, Mingfang Xu, Zhengang Sun, Xiao Yu, Yan Deng & Hong Chang. (2019) LINC01018 confers a novel tumor suppressor role in hepatocellular carcinoma through sponging microRNA-182-5p. American Journal of Physiology-Gastrointestinal and Liver Physiology 317:2, pages G116-G126.
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Feiyu Shi, Tian Li, Zhi Liu, Kai Qu, Chengxin Shi, Yaguang Li, Qian Qin, Liang Cheng, Xin Jin, Tianyu Yu, Wencheng Di, Jianwen Que, Hongping Xia & Junjun She. (2018) FOXO1: Another avenue for treating digestive malignancy?. Seminars in Cancer Biology 50, pages 124-131.
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Xia Yang, Yu-Yan Pang, Rong-Quan He, Peng Lin, Jie-Mei Cen, Hong Yang, Jie Ma & Gang Chen. (2018) Diagnostic value of strand-specific miRNA-101-3p and miRNA-101-5p for hepatocellular carcinoma and a bioinformatic analysis of their possible mechanism of action. FEBS Open Bio 8:1, pages 64-84.
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Jingyi Jiang, Zheng Liu, Chao Ge, Cong Chen, Fangyu Zhao, Hong Li, Taoyang Chen, Ming Yao & Jinjun Li. (2017) NK3 homeobox 1 (NKX3.1) up-regulates forkhead box O1 expression in hepatocellular carcinoma and thereby suppresses tumor proliferation and invasion. Journal of Biological Chemistry 292:47, pages 19146-19159.
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Dong-Yao Wang, Yan Cao, Le-Yi Zheng, Lang-Dong Chen, Xiao-Fei Chen, Zhan-Ying Hong, Zhen-Yu Zhu, Xiaoyu Li & Yi-Feng Chai. (2017) Target Identification of Kinase Inhibitor Alisertib (MLN8237) by Using DNA-Programmed Affinity Labeling. Chemistry - A European Journal 23:45, pages 10906-10914.
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Yue-Bin Zeng, Xing-Hua Liang, Guang-Xian Zhang, Nan Jiang, Tong Zhang, Jian-Ying Huang, Lei Zhang & Xian-Cheng Zeng. (2016) miRNA-135a promotes hepatocellular carcinoma cell migration and invasion by targeting forkhead box O1. Cancer Cell International 16:1.
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HAO XU, GUANGMING LI, ZHANYI YUE & CHENGZHONG LI. (2016) HCV core protein-induced upregulation of microRNA-196a promotes aberrant proliferation in hepatocellular carcinoma by targeting FOXO1. Molecular Medicine Reports 13:6, pages 5223-5229.
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Heping Kan, Yuqi Huang, Xianghong Li, Dingli Liu, Jianjia Chen & Miaojiang Shu. (2016) Zinc finger protein ZBTB20 is an independent prognostic marker and promotes tumor growth of human hepatocellular carcinoma by repressing FoxO1. Oncotarget 7:12, pages 14336-14349.
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Ye Cheng, Yunqian Li, Chengyuan Ma, Yang Song, Haiyang Xu, Hongquan Yu, Songbai Xu, Qingchun Mu, Haisong Li, Yong Chen & Gang Zhao. (2016) Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction. Oncotarget 7:11, pages 12682-12692.
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Arthur ZimmermannArthur Zimmermann. 2016. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract. Tumors and Tumor-Like Lesions of the Hepatobiliary Tract 1 13 .
Kate Cameron, Rosanne Tan, Wolfgang Schmidt-Heck, Gisela Campos, Marcus J. Lyall, Yu Wang, Baltasar Lucendo-Villarin, Dagmara Szkolnicka, Nicola Bates, Susan J. Kimber, Jan G. Hengstler, Patricio Godoy, Stuart J. Forbes & David C. Hay. (2015) Recombinant Laminins Drive the Differentiation and Self-Organization of hESC-Derived Hepatocytes. Stem Cell Reports 5:6, pages 1250-1262.
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Chao Tan, Shun Liu, Shengkui Tan, Xiaoyun Zeng, Hongping Yu, Anhua Li, Chunhua Bei & Xiaoqiang Qiu. (2015) Polymorphisms in MicroRNA Target Sites of Forkhead Box O Genes Are Associated with Hepatocellular Carcinoma. PLOS ONE 10:3, pages e0119210.
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Y Zhang, J Dai, H Deng, H Wan, M Liu, J Wang, S Li, X Li & H Tang. (2014) miR-1228 promotes the proliferation and metastasis of hepatoma cells through a p53 forward feedback loop. British Journal of Cancer 112:2, pages 365-374.
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Hye Sun Jung, Yu-Ri Seo, Yoon Mee Yang, Ja Hyun Koo, Jihyun An, Seung Jin Lee, Kang Mo Kim & Sang Geon Kim. (2014) Gα12 gep oncogene inhibits FOXO1 in hepatocellular carcinoma as a consequence of miR-135b and miR-194 dysregulation. Cellular Signalling 26:7, pages 1456-1465.
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Tian-Huei Chu, Hoi-Hung Chan, Hsiao-Mei Kuo, Li-Fen Liu, Tsung-Hui Hu, Cheuk-Kwan Sun, Mei-Lang Kung, Shih-Wei Lin, E-Ming Wang, Yi-Ling Ma, Kwan-Hung Cheng, Kwok Hung Lai, Zhi-Hong Wen, Ping-I Hsu & Ming-Hong Tai. (2013) Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN. Oncotarget 5:6, pages 1475-1490.
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FANG YU, LIANG JIN, GUODONG YANG, LIN JI, FENG WANG & ZIFAN LU. (2014) Post-transcriptional repression of FOXO1 by QKI results in low levels of FOXO1 expression in breast cancer cells. Oncology Reports 31:3, pages 1459-1465.
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