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Olga V Leontieva, Geraldine M Paszkiewicz & Mikhail V Blagosklonny. (2014) Comparison of rapamycin schedules in mice on high-fat diet. Cell Cycle 13:21, pages 3350-3356.
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Olga V Leontieva, Geraldine M Paszkiewicz & Mikhail V Blagosklonny. (2014) Fasting levels of hepatic p-S6 are increased in old mice. Cell Cycle 13:17, pages 2656-2659.
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Articles from other publishers (37)
Irene Bertolini, Michela Perego, Yulia Nefedova, Cindy Lin, Andrew Milcarek, Peter Vogel, Jagadish C. Ghosh, Andrew V. Kossenkov & Dario C. Altieri. (2023) Intercellular hif1α reprograms mammary progenitors and myeloid immune evasion to drive high-risk breast lesions. Journal of Clinical Investigation 133:8.
Crossref
Crossref
Zofia Chrienova, David Rysanek, Patrik Oleksak, Dorota Stary, Marek Bajda, Milan Reinis, Romana Mikyskova, Ondrej Novotny, Rudolf Andrys, Adam Skarka, Pavla Vasicova, Josef Novak, Martin Valis, Kamil Kuca, Zdenek Hodny & Eugenie Nepovimova. (2022) Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics. Frontiers in Aging Neuroscience 14.
Crossref
Crossref
Tània Cemeli, Marta Guasch-Vallés, Marina Ribes-Santolaria, Eva Ibars, Raúl Navaridas, Xavier Dolcet, Neus Pedraza, Neus Colomina, Jordi Torres-Rosell, Francisco Ferrezuelo, Judit Herreros & Eloi Garí. (2022) Antitumor Effects of Ral-GTPases Downregulation in Glioblastoma. International Journal of Molecular Sciences 23:15, pages 8199.
Crossref
Crossref
Zhigang Zhang, He N. Xu, Siyu Li, Antonio Davila Jr, Karthikeyani Chellappa, James G. Davis, Yuxia Guan, David W. Frederick, Weiqing Chu, Huaqing Zhao, Lin Z. Li & Joseph A. Baur. (2020) Rapamycin maintains NAD+/NADH redox homeostasis in muscle cells. Aging 12:18, pages 17786-17799.
Crossref
Crossref
V. A. Kobliakov. (2019) The Mechanisms of Regulation of Aerobic Glycolysis (Warburg Effect) by Oncoproteins in Carcinogenesis. Biochemistry (Moscow) 84:10, pages 1117-1128.
Crossref
Crossref
Gang Wang, Jun‐Jie Wang, Pei‐Hao Yin, Ke Xu, Yu‐Zhu Wang, Feng Shi, Jing Gao & Xing‐Li Fu. (2018) New strategies for targeting glucose metabolism–mediated acidosis for colorectal cancer therapy. Journal of Cellular Physiology 234:1, pages 348-368.
Crossref
Crossref
Hannah Walters & Lynne Cox. (2018) mTORC Inhibitors as Broad-Spectrum Therapeutics for Age-Related Diseases. International Journal of Molecular Sciences 19:8, pages 2325.
Crossref
Crossref
Alexander Aliper, Leslie Jellen, Franco Cortese, Artem Artemov, Darla Karpinsky-Semper, Alexey Moskalev, Andrew G. Swick & Alex Zhavoronkov. (2017) Towards natural mimetics of metformin and rapamycin. Aging 9:11, pages 2245-2268.
Crossref
Crossref
Brigitte Altmann, Lamprini Karygianni, Ali Al-Ahmad, Frank Butz, Maria Bächle, Erik Adolfsson, Tobias Fürderer, Nicolas Courtois, Paola Palmero, Marie Follo, Jérôme Chevalier, Thorsten Steinberg & Ralf Joachim Kohal. (2017) Assessment of Novel Long-Lasting Ceria-Stabilized Zirconia-Based Ceramics with Different Surface Topographies as Implant Materials. Advanced Functional Materials 27:40, pages 1702512.
Crossref
Crossref
Gemma Di Pompo, Silvia Lemma, Lorenzo Canti, Nadia Rucci, Marco Ponzetti, Costantino Errani, Davide Maria Donati, Shonagh Russell, Robert Gillies, Tokuhiro Chano, Nicola Baldini & Sofia Avnet. (2017) Intratumoral acidosis fosters cancer-induced bone pain through the activation of the mesenchymal tumor-associated stroma in bone metastasis from breast carcinoma. Oncotarget 8:33, pages 54478-54496.
Crossref
Crossref
Jun Hu, Yangfan Nie, Shifeng Chen, Chunlin Xie, Qiwen Fan, Zhichang Wang, Baisheng Long, Guokai Yan, Qing Zhong & Xianghua Yan. (2017) Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells. The International Journal of Biochemistry & Cell Biology 89, pages 42-56.
Crossref
Crossref
Mikhail V. Blagosklonny. (2017) From rapalogs to anti-aging formula. Oncotarget 8:22, pages 35492-35507.
Crossref
Crossref
Jiang-Tao Zhong & Shui-Hong Zhou. (2016) Warburg effect, hexokinase-II, and radioresistance of laryngeal carcinoma. Oncotarget 8:8, pages 14133-14146.
Crossref
Crossref
Olga V. Leontieva & Mikhail V. Blagosklonny. (2016) Gerosuppression by pan-mTOR inhibitors. Aging 8:12, pages 3535-3551.
Crossref
Crossref
Adrienne Wang, Jacob Mouser, Jason Pitt, Daniel Promislow & Matt Kaeberlein. (2016)
Rapamycin enhances survival in a
Drosophila
model of mitochondrial disease
. Oncotarget 7:49, pages 80131-80139.
Crossref
Crossref
Ezequiel Dantas, Fernando Erra Díaz, Pehuén Pereyra Gerber, Antonela Merlotti, Augusto Varese, Matías Ostrowski, Juan Sabatté & Jorge Geffner. (2016) Low pH impairs complement-dependent cytotoxicity against IgG-coated target cells. Oncotarget 7:45, pages 74203-74216.
Crossref
Crossref
Elena Lopez-Guadamillas, Maribel Muñoz-Martin, Sonia Martinez, Joaquin Pastor, Pablo J. Fernandez-Marcos & Manuel Serrano. (2016) PI3Kα inhibition reduces obesity in mice. Aging 8:11, pages 2747-2753.
Crossref
Crossref
Javier A. Menendez, Núria Folguera-Blasco, Elisabet Cuyàs, Salvador Fernández-Arroyo, Jorge Joven & Tomás Alarcón. (2016) Accelerated geroncogenesis in hereditary breast-ovarian cancer syndrome. Oncotarget 7:11, pages 11959-11971.
Crossref
Crossref
E. Paul Cherniack. 2016. Molecular Basis of Nutrition and Aging. Molecular Basis of Nutrition and Aging
649
657
.
Wenjie Qin, Chao Li, Wen Zheng, Qingqu Guo, Yuefeng Zhang, Muxing Kang, Bo Zhang, Bin Yang, Baozhong Li, Haijun Yang & Yulian Wu. (2015) Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells. Oncotarget 6:37, pages 39839-39854.
Crossref
Crossref
Balkrishna Chaube, Parmanand Malvi, Shivendra Vikram Singh, Naoshad Mohammad, Avtar Singh Meena & Manoj Kumar Bhat. (2015) Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression. Oncotarget 6:35, pages 37281-37299.
Crossref
Crossref
Lan Yu, Zeng-Fu Shang, Jian Wang, Hongtao Wang, Fang Huang, Zhe Zhang, Ying Wang, Jianguang Zhou & Shanhu Li. (2015) PC-1/PrLZ confers resistance to rapamycin in prostate cancer cells through increased 4E-BP1 stability. Oncotarget 6:24, pages 20356-20369.
Crossref
Crossref
Surendra K. Shukla, Venugopal Gunda, Jaime Abrego, Dhanya Haridas, Anusha Mishra, Joshua Souchek, Nina V. Chaika, Fang Yu, Aaron R. Sasson, Audrey J. Lazenby, Surinder K. Batra & Pankaj K. Singh. (2015) MUC16-mediated activation of mTOR and c-MYC reprograms pancreatic cancer metabolism. Oncotarget 6:22, pages 19118-19131.
Crossref
Crossref
M.-G. Ryou, G.R. Choudhury, W. Li, A. Winters, F. Yuan, R. Liu & S.-H. Yang. (2015) Methylene blue-induced neuronal protective mechanism against hypoxia-reoxygenation stress. Neuroscience 301, pages 193-203.
Crossref
Crossref
Maria Luisa GenovaGiorgio Lenaz. (2015) The Interplay Between Respiratory Supercomplexes and ROS in Aging. Antioxidants & Redox Signaling 23:3, pages 208-238.
Crossref
Crossref
Libin Wei, Yuxin Zhou, Jing Yao, Chen Qiao, Ting Ni, Ruichen Guo, Qinglong Guo & Na Lu. (2015) Lactate promotes PGE2 synthesis and gluconeogenesis in monocytes to benefit the growth of inflammation-associated colorectal tumor. Oncotarget 6:18, pages 16198-16214.
Crossref
Crossref
Concetta Ferretti, Guendalina Lucarini, Chiara Andreoni, Eleonora Salvolini, Novella Bianchi, Giovanni Vozzi, Antonio Gigante & Monica Mattioli-Belmonte. (2014) Human Periosteal Derived Stem Cell Potential: The Impact of age. Stem Cell Reviews and Reports 11:3, pages 487-500.
Crossref
Crossref
Weiqi Dai, Fan Wang, Jie Lu, Yujing Xia, Lei He, Kan Chen, Jingjing Li, Sainan Li, Tong Liu, Yuanyuan Zheng, Jianrong Wang, Wenxia Lu, Yuqing Zhou, Qin Yin, Huerxidan Abudumijiti, Rongxia Chen, Rong Zhang, Li Zhou, Zheng Zhou, Rong Zhu, Jing Yang, Chengfen Wang, Huawei Zhang, Yingqun Zhou, Ling Xu & Chuanyong Guo. (2015) By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice. Oncotarget 6:15, pages 13703-13717.
Crossref
Crossref
Haifeng Qiu, Amanda L. Jackson, Joshua E. Kilgore, Yan Zhong, Leo Li-Ying Chan, Paola A. Gehrig, Chunxiao Zhou & Victoria L. Bae-Jump. (2015) JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer*. Oncotarget 6:9, pages 6915-6930.
Crossref
Crossref
Chunyan Li, Gang Meng, Lei Su, Aiping Chen, Mao Xia, Chun Xu, Decai Yu, Aiqin Jiang & Jiwu Wei. (2014) Dichloroacetate blocks aerobic glycolytic adaptation to attenuated measles virus and promotes viral replication leading to enhanced oncolysis in glioblastoma. Oncotarget 6:3, pages 1544-1555.
Crossref
Crossref
Rafaela Andrade-Vieira, Donna Goguen, Heidi A. Bentley, Chris V. Bowen & Paola A. Marignani. (2014) Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss. Oncotarget 5:24, pages 12738-12752.
Crossref
Crossref
M V Blagosklonny. (2014) Koschei the immortal and anti-aging drugs. Cell Death & Disease 5:12, pages e1552-e1552.
Crossref
Crossref
Yue-Zhi Lee, Cheng-Wei Yang, Hsin-Yu Chang, Hsing-Yu Hsu, Ih-Shen Chen, Hsun-Shuo Chang, Chih-Hao Lee, Jinq-chyi Lee, Chidambaram Ramesh Kumar, Ya-Qi Qiu, Yu-Sheng Chao & Shiow-Ju Lee. (2014) Discovery of selective inhibitors of Glutaminase-2, which inhibit mTORC1, activate autophagy and inhibit proliferation in cancer cells. Oncotarget 5:15, pages 6087-6101.
Crossref
Crossref
Calvin Tebbe, Jasdeep Chhina, Sajad A. Dar, Kalli Sarigiannis, Shailendra Giri, Adnan R. Munkarah & Ramandeep Rattan. (2014) Metformin limits the adipocyte tumor-promoting effect on ovarian cancer. Oncotarget 5:13, pages 4746-4764.
Crossref
Crossref
Chiara Agnoletto, Elisabetta Melloni, Fabio Casciano, Gian Matteo Rigolin, Erika Rimondi, Claudio Celeghini, Laura Brunelli, Antonio Cuneo, Paola Secchiero & Giorgio Zauli. (2014) Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3. Oncotarget 5:12, pages 4347-4360.
Crossref
Crossref
Anna Pastò, Chiara Bellio, Giorgia Pilotto, Vincenzo Ciminale, Micol Silic-Benussi, Giulia Guzzo, Andrea Rasola, Chiara Frasson, Giorgia Nardo, Elisabetta Zulato, Maria Ornella Nicoletto, Mariangela Manicone, Stefano Indraccolo & Alberto Amadori. (2014) Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation. Oncotarget 5:12, pages 4305-4319.
Crossref
Crossref
O V Leontieva, Z N Demidenko & M V Blagosklonny. (2014) Rapamycin reverses insulin resistance (IR) in high-glucose medium without causing IR in normoglycemic medium. Cell Death & Disease 5:5, pages e1214-e1214.
Crossref
Crossref