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Andrew Dolson, Safia Mahabub Sauty, Kholoud Shaban & Krassimir Yankulov. (2021) Dbf4-Dependent Kinase: DDK-ated to post-initiation events in DNA replication. Cell Cycle 20:22, pages 2348-2360.
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Hisao Masai. (2017) A novel p53-Cdc7 link induced by genotoxic stress. Cell Cycle 16:8, pages 735-736.
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Slavica Tudzarova, Paul Mulholland, Ayona Dey, Kai Stoeber, Andrei L. Okorokov & Gareth H. Williams. (2016) p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress. Cell Cycle 15:21, pages 2958-2972.
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Kengo Tanigawa, Yuya Tomioka, Shunsuke Misono, Shunichi Asai, Naoko Kikkawa, Yoko Hagihara, Takayuki Suetsugu, Hiromasa Inoue, Keiko Mizuno & Naohiko Seki. (2023) Minichromosome maintenance proteins in lung adenocarcinoma: Clinical significance and therapeutic targets. FEBS Open Bio.
Crossref
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Cristina González‐Garrido & Félix Prado. (2022) Novel insights into the roles of Cdc7 in response to replication stress. The FEBS Journal 290:12, pages 3076-3088.
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Jay Anand, Lilly Chiou, Carly Sciandra, Xingyuan Zhang, Jiyong Hong, Di Wu, Pei Zhou & Cyrus Vaziri. (2023) Roles of trans-lesion synthesis (TLS) DNA polymerases in tumorigenesis and cancer therapy. NAR Cancer 5:1.
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Elena Piletska, Dana Thompson, Rebecca Jones, Alvaro Garcia Cruz, Marta Poblocka, Francesco Canfarotta, Rachel Norman, Salvador Macip, Donald J. L. Jones & Sergey Piletsky. (2022) Snapshot imprinting as a tool for surface mapping and identification of novel biomarkers of senescent cells. Nanoscale Advances 4:24, pages 5304-5311.
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Jeffrey C. Martin, Jennie R. Sims, Ajay Gupta, Andrei V. Bakin & Joyce Ellen Ohm. (2022) WEE1 Inhibition Augments CDC7 (DDK) Inhibitor–induced Cell Death in Ewing Sarcoma by Forcing Premature Mitotic Entry and Mitotic Catastrophe. Cancer Research Communications 2:6, pages 471-482.
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Runze Liu & Yong Huang. (2022) CDC7 as a novel biomarker and druggable target in cancer. Clinical and Translational Oncology 24:10, pages 1856-1864.
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Almutasem Saleh, Yasunori Noguchi, Ricardo Aramayo, Marina E. Ivanova, Kathryn M. Stevens, Alex Montoya, S. Sunidhi, Nicolas Lopez Carranza, Marcin J. Skwark & Christian Speck. (2022) The structural basis of Cdc7-Dbf4 kinase dependent targeting and phosphorylation of the MCM2-7 double hexamer. Nature Communications 13:1.
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Chinnu Rose Joseph, Sabrina Dusi, Michele Giannattasio & Dana Branzei. (2022) Rad51-mediated replication of damaged templates relies on monoSUMOylated DDK kinase. Nature Communications 13:1.
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Xiaofei Zhou, Aziz Ouerdani, Paul Matthias Diderichsen & Neeraj Gupta. (2021) Population Pharmacokinetics of TAK‐931, a Cell Division Cycle 7 Kinase Inhibitor, in Patients With Advanced Solid Tumors. The Journal of Clinical Pharmacology 62:3, pages 422-433.
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Jeffrey C. Martin, Jennie R. Sims, Ajay Gupta, Tamara J. Hagoel, Lingqiu Gao, Miranda L. Lynch, Anna Woloszynska, Thomas Melendy, Jeremy F. Kane, Joseph Kuechle & Joyce E. Ohm. (2022) CDC7 kinase (DDK) inhibition disrupts DNA replication leading to mitotic catastrophe in Ewing sarcoma. Cell Death Discovery 8:1.
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Shalini Aricthota & Devyani Haldar. (2021) DDK/Hsk1 phosphorylates and targets fission yeast histone deacetylase Hst4 for degradation to stabilize stalled DNA replication forks. eLife 10.
Crossref
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Kenichi Iwai, Tadahiro Nambu, Yukie KashimaJie Yu, Kurt Eng, Kazumasa Miyamoto, Kazuyo KakoiMasamitsu GotouToshiyuki TakeuchiAkifumi Kogame, Jessica SappalSaomi MuraiHiroshi HaenoShun-Ichiro Kageyama, Osamu Kurasawa, Huifeng Niu, Karuppiah KannanAkihiro Ohashi. (2021) A CDC7 inhibitor sensitizes DNA-damaging chemotherapies by suppressing homologous recombination repair to delay DNA damage recovery. Science Advances 7:21.
Crossref
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Liang Chang, Paloma Ruiz, Takahiro Ito & William R. Sellers. (2021) Targeting pan-essential genes in cancer: Challenges and opportunities. Cancer Cell 39:4, pages 466-479.
Crossref
Crossref
Mirella Baroni, Caihong Yi, Saket Choudhary, Xiufen Lei, Adam Kosti, Denise Grieshober, Mitzli Velasco, Mei Qiao, Suzanne Burns, Patricia Araujo, Talia DeLambre, Mi Son, Michelina Plateroti, Marco Ferreira, Paul Hasty & Luiz Penalva. (2021) Musashi1 Contribution to Glioblastoma Development via Regulation of a Network of DNA Replication, Cell Cycle and Division Genes. Cancers 13:7, pages 1494.
Crossref
Crossref
Michael D Rainey, Aisling Quinlan, Chiara Cazzaniga, Sofija Mijic, Oliviano Martella, Jana Krietsch, Anja Göder, Massimo Lopes & Corrado Santocanale. (2020) CDC7 kinase promotes MRE11 fork processing, modulating fork speed and chromosomal breakage. EMBO reports 21:8.
Crossref
Crossref
Ronan P. McLaughlin, Jichao He, Vera E. van der Noord, Jevin Redel, John A. Foekens, John W. M. Martens, Marcel Smid, Yinghui Zhang & Bob van de Water. (2019) A kinase inhibitor screen identifies a dual cdc7/CDK9 inhibitor to sensitise triple-negative breast cancer to EGFR-targeted therapy. Breast Cancer Research 21:1.
Crossref
Crossref
Albrecht & Kübler. (2019) Systematic Meta-Analysis Identifies Co-Expressed Kinases and GPCRs in Ovarian Cancer Tissues Revealing a Potential for Targeted Kinase Inhibitor Delivery. Pharmaceutics 11:9, pages 454.
Crossref
Crossref
Kenichi Iwai, Tadahiro Nambu, Ryo DairikiMomoko OhoriJie Yu, Kristine Burke, Masamitsu GotouYukiko YamamotoShunsuke Ebara, Sachio Shibata, Ryosuke HibinoSatoru NishizawaTohru MiyazakiMisaki HommaYuya OguroTakashi Imada, Nobuo Cho, Noriko UchiyamaAkifumi KogameToshiyuki TakeuchiOsamu Kurasawa, Kazunori YamanakaHuifeng Niu & Akihiro Ohashi. (2019) Molecular mechanism and potential target indication of TAK-931, a novel CDC7-selective inhibitor. Science Advances 5:5.
Crossref
Crossref
Tiffany J Young, Yi Cui, Joseph Irudayaraj & Ann L Kirchmaier. (2019)
Modulation of Gene Silencing by Cdc7p via H4 K16 Acetylation and Phosphorylation of Chromatin Assembly Factor CAF-1 in
Saccharomyces cerevisiae
. Genetics 211:4, pages 1219-1237.
Crossref
Crossref
Diletta Ciardo, Arach Goldar & Kathrin Marheineke. (2019) On the Interplay of the DNA Replication Program and the Intra-S Phase Checkpoint Pathway. Genes 10:2, pages 94.
Crossref
Crossref
Xinjian Li, Xu Qian, Hongfei Jiang, Yan Xia, Yanhua Zheng, Jing Li, Bi-Jun Huang, Jing Fang, Chao-Nan Qian, Tao Jiang, Yi-Xin Zeng & Zhimin Lu. (2018) Nuclear PGK1 Alleviates ADP-Dependent Inhibition of CDC7 to Promote DNA Replication. Molecular Cell 72:4, pages 650-660.e8.
Crossref
Crossref
Shufang Jin, Hailong Ma, Wenyi Yang, Houyu Ju, Lizhen Wang & Zhiyuan Zhang. (2018) Cell division cycle 7 is a potential therapeutic target in oral squamous cell carcinoma and is regulated by E2F1. Journal of Molecular Medicine 96:6, pages 513-525.
Crossref
Crossref
Tatiana Moiseeva, Brian Hood, Sandy Schamus, Mark J. O’Connor, Thomas P. Conrads & Christopher J. Bakkenist. (2017) ATR kinase inhibition induces unscheduled origin firing through a Cdc7-dependent association between GINS and And-1. Nature Communications 8:1.
Crossref
Crossref
Arindam Datta, Dishari Ghatak, Sumit Das, Taraswi Banerjee, Anindita Paul, Ramesh Butti, Mahadeo Gorain, Sangeeta Ghuwalewala, Anirban Roychowdhury, Sk Kayum Alam, Pijush Das, Raghunath Chatterjee, Maitrayee Dasgupta, Chinmay Kumar Panda, Gopal C Kundu & Susanta Roychoudhury. (2017) p53 gain‐of‐function mutations increase Cdc7‐dependent replication initiation. EMBO reports 18:11, pages 2030-2050.
Crossref
Crossref
Michael D. Rainey, Huong Quachthithu, David Gaboriau & Corrado Santocanale. (2017) DNA Replication Dynamics and Cellular Responses to ATP Competitive CDC7 Kinase Inhibitors. ACS Chemical Biology 12:7, pages 1893-1902.
Crossref
Crossref
Anna Herlihy & Robertus de Bruin. (2017) The Role of the Transcriptional Response to DNA Replication Stress. Genes 8:3, pages 92.
Crossref
Crossref
Sharon B. Cantor & Jennifer A. Calvo. (2017) Fork Protection and Therapy Resistance in Hereditary Breast Cancer. Cold Spring Harbor Symposia on Quantitative Biology 82, pages 339-348.
Crossref
Crossref
Cosetta Bertoli, Anna E. Herlihy, Betheney R. Pennycook, Janos Kriston-Vizi & Robertus A.M. de Bruin. (2016) Sustained E2F-Dependent Transcription Is a Key Mechanism to Prevent Replication-Stress-Induced DNA Damage. Cell Reports 15:7, pages 1412-1422.
Crossref
Crossref
Takashi Nonaka, Genjiro Suzuki, Yoshinori Tanaka, Fuyuki Kametani, Shinobu Hirai, Haruo Okado, Tomoyuki Miyashita, Minoru Saitoe, Haruhiko Akiyama, Hisao Masai & Masato Hasegawa. (2016) Phosphorylation of TAR DNA-binding Protein of 43 kDa (TDP-43) by Truncated Casein Kinase 1δ Triggers Mislocalization and Accumulation of TDP-43. Journal of Biological Chemistry 291:11, pages 5473-5483.
Crossref
Crossref
Dany Graindorge, Sylvain Martineau, Christelle Machon, Philippe Arnoux, Jérôme Guitton, Stefania Francesconi, Céline Frochot, Evelyne Sage & Pierre-Marie Girard. (2015) Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication. PLOS ONE 10:10, pages e0140645.
Crossref
Crossref
Matthias Dobbelstein & Claus Storgaard Sørensen. (2015) Exploiting replicative stress to treat cancer. Nature Reviews Drug Discovery 14:6, pages 405-423.
Crossref
Crossref