495
Views
58
CrossRef citations to date
0
Altmetric
Review

Many Fingers on the Mitotic Trigger: Post-Translational Regulation of the Cdc25C Phosphatase

Pages 40-44 | Published online: 10 Sep 2003

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (5)

Junfeng Liu, Yu Liu, Tao Xie, Longjun Luo, Cheng Xu, Qinglei Gao, Lu Shen, Feng Wan, Ting Lei & Fei Ye. (2018) Radiation-induced G2/M arrest rarely occurred in glioblastoma stem-like cells. International Journal of Radiation Biology 94:4, pages 394-402.
Read now
Jun Xue, Yan Zong, Pin-Dong Li, Li-Xia Wang, Yun-Qiao Li & Yan-Feng Niu. (2016) Low-dose hyper-radiosensitivity in human hepatocellular HepG2 cells is associated with Cdc25C-mediated G2/M cell cycle checkpoint control. International Journal of Radiation Biology 92:10, pages 543-547.
Read now
Nithya Krishnan, TuKiet T. Lam, Andrew Fritz, Donald Rempinski, Kieran O'Loughlin, Hans Minderman, Ronald Berezney, William F. Marzluff & Roopa Thapar. (2012) The Prolyl Isomerase Pin1 Targets Stem-Loop Binding Protein (SLBP) To Dissociate the SLBP-Histone mRNA Complex Linking Histone mRNA Decay with SLBP Ubiquitination. Molecular and Cellular Biology 32:21, pages 4306-4322.
Read now
Silvia Senese, Katrin Zaragoza, Simone Minardi, Ivan Muradore, Simona Ronzoni, Alfonso Passafaro, Loris Bernard, Giulio F. Draetta, Myriam Alcalay, Christian Seiser & Susanna Chiocca. (2007) Role for Histone Deacetylase 1 in Human Tumor Cell Proliferation. Molecular and Cellular Biology 27:13, pages 4784-4795.
Read now
Sun Young Kim, Eun Joo Song, Kong-Joo Lee & James E. Ferrell$suffix/text()$suffix/text(). (2005) Multisite M-Phase Phosphorylation of Xenopus Wee1A. Molecular and Cellular Biology 25:23, pages 10580-10590.
Read now

Articles from other publishers (53)

Peter C. Heinrich, Hans-Georg Koch & Jan Brix. 2022. Löffler/Petrides Biochemie und Pathobiochemie. Löffler/Petrides Biochemie und Pathobiochemie 695 706 .
Kai Liu, Minying Zheng, Rui Lu, Jiaxing Du, Qi Zhao, Zugui Li, Yuwei Li & Shiwu Zhang. (2020) The role of CDC25C in cell cycle regulation and clinical cancer therapy: a systematic review. Cancer Cell International 20:1.
Crossref
Karine Flem-Karlsen, Erin McFadden, Nasrin Omar, Mads H. Haugen, Geir Frode Øy, Truls Ryder, Hans Petter Gullestad, Robert Hermann, Gunhild Mari Mælandsmo & Vivi Ann Flørenes. (2020) Targeting AXL and the DNA Damage Response Pathway as a Novel Therapeutic Strategy in Melanoma. Molecular Cancer Therapeutics 19:3, pages 895-905.
Crossref
Adrijana Crncec & Helfrid Hochegger. (2019) Triggering mitosis. FEBS Letters 593:20, pages 2868-2888.
Crossref
Ken-ichiro AbeSatoshi FunayaDai TsukiokaMachika KawamuraYutaka SuzukiMasataka G. SuzukiRichard M. Schultz & Fugaku Aoki. (2018) Minor zygotic gene activation is essential for mouse preimplantation development. Proceedings of the National Academy of Sciences 115:29.
Crossref
C Dozier, L Mazzolini, C Cénac, C Froment, O Burlet-Schiltz, A Besson & S Manenti. (2017) CyclinD-CDK4/6 complexes phosphorylate CDC25A and regulate its stability. Oncogene 36:26, pages 3781-3788.
Crossref
Isabel Myriam Schopp, Cinthia Claudia Amaya Ramirez, Jerneja Debeljak, Elisa Kreibich, Merle Skribbe, Klemens Wild & Julien Béthune. (2017) Split-BioID a conditional proteomics approach to monitor the composition of spatiotemporally defined protein complexes. Nature Communications 8:1.
Crossref
Gangyang Wang, Tao Zhang, Wei Sun, Hongsheng Wang, Fei Yin, Zhuoying Wang, Dongqing Zuo, Mengxiong Sun, Zifei Zhou, Binhui Lin, Jing Xu, Yingqi Hua, Haoqing Li & Zhengdong Cai. (2017) Arsenic sulfide induces apoptosis and autophagy through the activation of ROS/JNK and suppression of Akt/mTOR signaling pathways in osteosarcoma. Free Radical Biology and Medicine 106, pages 24-37.
Crossref
Fei fei Ma, Ding ding Cao, Shengrong Ouyang, Renqiao Tang, Zhuo Liu, Yuanyuan Li & Jianxin Wu. (2016) Hypermethylation of AKT2 gene is associated with neural-tube defects in fetus. Placenta 48, pages 80-86.
Crossref
Shuit-Mun Wong, Fu-Hwa Liu, Yueh-Lun Lee & Huei-Mei Huang. (2016) MPT0B169, a New Antitubulin Agent, Inhibits Bcr-Abl Expression and Induces Mitochondrion-Mediated Apoptosis in Nonresistant and Imatinib-Resistant Chronic Myeloid Leukemia Cells. PLOS ONE 11:1, pages e0148093.
Crossref
Brian Gabrielli & Andrew Burgess. 2016. Protein Tyrosine Phosphatases in Cancer. Protein Tyrosine Phosphatases in Cancer 283 306 .
David W. Litchfield, Brian H. Shilton, Christopher J. Brandl & Laszlo Gyenis. (2015) Pin1: Intimate involvement with the regulatory protein kinase networks in the global phosphorylation landscape. Biochimica et Biophysica Acta (BBA) - General Subjects 1850:10, pages 2077-2086.
Crossref
Garam Kim, Jin Young Kim & Hong Seok Choi. (2015) Peptidyl–Prolyl <i>cis</i>/<i>trans</i> Isomerase NIMA-Interacting 1 as a Therapeutic Target in Hepatocellular Carcinoma. Biological & Pharmaceutical Bulletin Biological and Pharmaceutical Bulletin 38:7, pages 975-979.
Crossref
Yong Xia, Qian Lei, Yongxia Zhu, Tinghong Ye, Ningyu Wang, Guobo Li, Xuanhong Shi, Yantong Liu, Bin Shao, Tao Yin, Lifeng Zhao, Wenshuang Wu, Xuejiao Song, Ying Xiong, Yuquan Wei & Luoting Yu. (2014) SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo. Cancer Letters 355:2, pages 297-309.
Crossref
Lin Li, Bei-bei Zheng, Li-sha Ma, Xiao Sun, Juan-juan Chang, Wei-dong Xie & Xia Li. (2014) Telekin suppresses human hepatocellular carcinoma cells in vitro by inducing G2/M phase arrest via the p38 MAPK signaling pathway. Acta Pharmacologica Sinica 35:10, pages 1311-1322.
Crossref
Vikas Pejaver, Wei-Lun Hsu, Fuxiao Xin, A. Keith Dunker, Vladimir N. Uversky & Predrag Radivojac. (2014) The structural and functional signatures of proteins that undergo multiple events of post-translational modification. Protein Science 23:8, pages 1077-1093.
Crossref
Haruhiro Toko, Nirmala Hariharan, Mathias H. Konstandin, Lucia Ormachea, Michael McGregor, Natalie A. Gude, Balaji Sundararaman, Eri Joyo, Anya Y. Joyo, Brett Collins, Shabana Din, Sadia Mohsin, Takafumi Uchida & Mark A. Sussman. (2014) Differential Regulation of Cellular Senescence and Differentiation by Prolyl Isomerase Pin1 in Cardiac Progenitor Cells. Journal of Biological Chemistry 289:9, pages 5348-5356.
Crossref
Wenshuang Wu, Haoyu Ye, Li Wan, Xiaolei Han, Guangcheng Wang, Jia Hu, Minhai Tang, Xingmei Duan, Yi Fan, Shichao He, Li Huang, Heying Pei, Xuewei Wang, Xiuxia Li, Caifeng Xie, Ronghong Zhang, Zhu Yuan, Yongqiu Mao, Yuquan Wei & Lijuan Chen. (2013) Millepachine, a novel chalcone, induces G 2 /M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo. Carcinogenesis 34:7, pages 1636-1643.
Crossref
Celine Franckhauser, Anne Fernandez & Ned J.C. Lamb. (2013) Purification and biochemical analysis of catalytically active human cdc25C dual specificity phosphatase. Biochimie 95:7, pages 1450-1461.
Crossref
Kevin J. Kesseler, Michael L. Blinov, Timothy C. Elston, William K. Kaufmann & Dennis A. Simpson. (2013) A predictive mathematical model of the DNA damage G2 checkpoint. Journal of Theoretical Biology 320, pages 159-169.
Crossref
Xueli Fan, Yingwang Liu, Susan A. Heilman & Jason J. Chen. (2013) Human Papillomavirus E7 Induces Rereplication in Response to DNA Damage. Journal of Virology 87:2, pages 1200-1210.
Crossref
Olga Jasnovidova & Richard Stefl. (2013) The CTD code of RNA polymerase II: a structural view. Wiley Interdisciplinary Reviews: RNA 4:1, pages 1-16.
Crossref
Marie A. Bogoyevitch, Yvonne Y. C. Yeap, Zhengdong Qu, Kevin R. Ngoei, Yan Y. Yip, Teresa T. Zhao, Julian I. Heng & Dominic C. H. Ng. (2012) WD40-repeat protein 62 is a JNK-phosphorylated spindle pole protein required for spindle maintenance and timely mitotic progression. Journal of Cell Science 125:21, pages 5096-5109.
Crossref
Aristoteles A.N. Giagounidis. (2012) Lenalidomide for del(5q) and Non-del(5q) Myelodysplastic Syndromes. Seminars in Hematology 49:4, pages 312-322.
Crossref
Y. Zhao, Y. Cui, J. Han, J. Ren, G. Wu & J. Cheng. (2012) Cell division cycle 25 homolog c effects on low-dose hyper-radiosensitivity and induced radioresistance at elevated dosage in A549 cells. Journal of Radiation Research 53:5, pages 686-694.
Crossref
Thomas Timm, Jens Peter von Kries, Xiaoyu Li, Hans Zempel, Eckhard Mandelkow & Eva-Maria Mandelkow. (2011) Microtubule Affinity Regulating Kinase Activity in Living Neurons Was Examined by a Genetically Encoded Fluorescence Resonance Energy Transfer/Fluorescence Lifetime Imaging-based Biosensor. Journal of Biological Chemistry 286:48, pages 41711-41722.
Crossref
Sunjoo Ahn, Charles B. DukeIIIIII, Christina M. Barrett, Dong Jin Hwang, Chien-Ming Li, Duane D. Miller & James T. Dalton. (2010) I-387, a Novel Antimitotic Indole, Displays a Potent In vitro and In vivo Antitumor Activity with Less Neurotoxicity . Molecular Cancer Therapeutics 9:11, pages 2859-2868.
Crossref
Fengxiang Wei, Yanyun Xie, Lijian Tao & Damu Tang. (2010) Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation. Cellular Signalling 22:11, pages 1783-1789.
Crossref
Celine Franckhauser, Daria Mamaeva, Lisa Heron-Milhavet, Anne Fernandez & Ned J. C. Lamb. (2010) Distinct Pools of cdc25C Are Phosphorylated on Specific TP Sites and Differentially Localized in Human Mitotic Cells. PLoS ONE 5:7, pages e11798.
Crossref
Jian Kuang & Ruoning Wang. 2009. Checkpoint Controls and Targets in Cancer Therapy. Checkpoint Controls and Targets in Cancer Therapy 37 51 .
Sheng WeiXianghong ChenKathy RochaP. K. Epling-BurnetteJulie Y. DjeuQing LiuJohn ByrdLubomir SokolNick LawrenceRoberta PiredduGordon DewaldAnn Williams, Jaroslaw Maciejewski & Alan List. (2009) A critical role for phosphatase haplodeficiency in the selective suppression of deletion 5q MDS by lenalidomide. Proceedings of the National Academy of Sciences 106:31, pages 12974-12979.
Crossref
Ali Pedram, Mahnaz Razandi, Albert J. Evinger, Eva Lee & Ellis R. Levin. (2009) Estrogen Inhibits ATR Signaling to Cell Cycle Checkpoints and DNA Repair. Molecular Biology of the Cell 20:14, pages 3374-3389.
Crossref
Carlos Salazar & Thomas Höfer. (2009) Multisite protein phosphorylation - from molecular mechanisms to kinetic models. FEBS Journal 276:12, pages 3177-3198.
Crossref
S. Cunat, T. Anahory, C. Berthenet, B. Hedon, C. Franckhauser, A. Fernandez, S. Hamamah & N.J.C. Lamb. (2007) The cell cycle control protein cdc25C is present, and phosphorylated on serine 214 in the transition from germinal vesicle to metaphase II in human oocyte meiosis. Molecular Reproduction and Development 75:7, pages 1176-1184.
Crossref
Jérôme Bonnet, Pauline Mayonove & May C. Morris. (2008) Differential phosphorylation of Cdc25C phosphatase in mitosis. Biochemical and Biophysical Research Communications 370:3, pages 483-488.
Crossref
Benjamin A. Smith-Donald, Lizette O. Durand & Bernard Roizman. (2008) Role of Cellular Phosphatase cdc25C in Herpes Simplex Virus 1 Replication. Journal of Virology 82:9, pages 4527-4532.
Crossref
Erin Knock, Liyuan Deng, Qing Wu, Andrea K. Lawrance, Xiao-ling Wang & Rima Rozen. (2008) Strain Differences in Mice Highlight the Role of DNA Damage in Neoplasia Induced by Low Dietary Folate. The Journal of Nutrition 138:4, pages 653-658.
Crossref
Takumi Kawabe. 2008. Checkpoint Responses in Cancer Therapy. Checkpoint Responses in Cancer Therapy 117 133 .
Craig M. Forester, Jessica Maddox, Justin V. Louis, Jozef Goris & David M. Virshup. (2007) Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1. Proceedings of the National Academy of Sciences 104:50, pages 19867-19872.
Crossref
Antara Datta, Lee Silverman, Andrew J Phipps, Hajime Hiraragi, Lee Ratner & Michael D Lairmore. (2007) Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival. Retrovirology 4:1.
Crossref
Parag Patwardhan & W. Todd Miller. (2007) Processive phosphorylation: Mechanism and biological importance. Cellular Signalling 19:11, pages 2218-2226.
Crossref
Lu Sun, Yingtao Chai, Robyn Hannigan, Venkata K. Bhogaraju & Khaled Machaca. (2007) Zinc regulates the ability of Cdc25C to activate MPF/cdk1. Journal of Cellular Physiology 213:1, pages 98-104.
Crossref
Rebecca Heald. (2007) Brinkley-Fest of Mitosis. Developmental Cell 13:2, pages 168-176.
Crossref
Aijing Sun, Ilanchezian Shanmugam, Jiawu Song, Paul F. Terranova, J. Brantley Thrasher & Benyi Li. (2007) Lithium suppresses cell proliferation by interrupting E2F–DNA interaction and subsequently reducing S–phase gene expression in prostate cancer. The Prostate 67:9, pages 976-988.
Crossref
Tsz Kan Fung, Hoi Tang Ma & Randy Y.C. Poon. (2007) Specialized Roles of the Two Mitotic Cyclins in Somatic Cells: Cyclin A as an Activator of M Phase–promoting Factor. Molecular Biology of the Cell 18:5, pages 1861-1873.
Crossref
Erin Knock, Liyuan Deng, Qing Wu, Daniel Leclerc, Xiao-ling Wang & Rima Rozen. (2006) Low Dietary Folate Initiates Intestinal Tumors in Mice, with Altered Expression of G2-M Checkpoint Regulators Polo-Like Kinase 1 and Cell Division Cycle 25c . Cancer Research 66:21, pages 10349-10356.
Crossref
Yi Sun, Yue-Chen Huang, Qin-Zhi Xu, Hui-Ping Wang, Bei Bai, Jian-Li Sui & Ping-Kun Zhou. (2006) HIV-1 Tat depresses DNA-PKCS expression and DNA repair, and sensitizes cells to ionizing radiation. International Journal of Radiation Oncology*Biology*Physics 65:3, pages 842-850.
Crossref
Thomas Köcher, Mikhail M. Savitski, Michael L. Nielsen & Roman A. Zubarev. (2006) PhosTShunter:  A Fast and Reliable Tool to Detect Phosphorylated Peptides in Liquid Chromatography Fourier Transform Tandem Mass Spectrometry Data Sets. Journal of Proteome Research 5:3, pages 659-668.
Crossref
Wei Zhang, Lynda Fletcher & Ruth J. Muschel. (2005) The Role of Polo-like Kinase 1 in the Inhibition of Centrosome Separation after Ionizing Radiation. Journal of Biological Chemistry 280:52, pages 42994-42999.
Crossref
ÍÑIgo Santamarea, Daniel elvarez-Hernendez, Rosa Jofre, Jose Ramen Polo, Javier Menerguez & Jorge B. Cannata-Andea. (2005) Progression of secondary hyperparathyroidism involves deregulation of genes related to DNA and RNA stability. Kidney International 67:6, pages 2267-2279.
Crossref
Xiang-Jiao Yang. (2004) Multisite protein modification and intramolecular signaling. Oncogene 24:10, pages 1653-1662.
Crossref
Dawn L. Darling, Jessica Yingling & Anthony Wynshaw‐Boris. 2005. 281 315 .
M. Gloria Luciani, Maren Oehlmann & J. Julian Blow. (2004) Characterization of a novel ATR-dependent, Chk1-independent, intra-S-phase checkpoint that suppresses initiation of replication in Xenopus . Journal of Cell Science 117:25, pages 6019-6030.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.