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Stress-Induced p53 Runs a Direct Mitochondrial Death Program: Its Role in Physiologic and Pathophysiologic Stress Responses In Vivo

Pages 1492-1495 | Published online: 28 Sep 2004

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Yuguang Zhao, Hongguang Zhao, Xujie Zhai, Junying Dai, Xin Jiang, Guanjun Wang, Wei Li & Lu Cai. (2013) Effects of Zn deficiency, antioxidants, and low-dose radiation on diabetic oxidative damage and cell death in the testis. Toxicology Mechanisms and Methods 23:1, pages 42-47.
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Franck Toledo, Crystal J. Lee, Kurt A. Krummel, Luo-Wei Rodewald, Chung-Wen Liu & Geoffrey M. Wahl. (2007) Mouse Mutants Reveal that Putative Protein Interaction Sites in the p53 Proline-Rich Domain Are Dispensable for Tumor Suppression. Molecular and Cellular Biology 27:4, pages 1425-1432.
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Seung Jae Hyeon, Jinyoung Park, Junsang Yoo, Su-Hyun Kim, Yu Jin Hwang, Seung-Chan Kim, Tian Liu, Hyun Soo Shim, Yunha Kim, Yakdol Cho, Jiwan Woo, Key-Sun Kim, Richard H. Myers, Hannah L. Ryu, Neil W. Kowall, Eun Joo Song, Eun Mi Hwang, Hyemyung Seo, Junghee Lee & Hoon Ryu. (2021) Dysfunction of X-linked inhibitor of apoptosis protein (XIAP) triggers neuropathological processes via altered p53 activity in Huntington’s disease. Progress in Neurobiology 204, pages 102110.
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I. V. Kastyro, I. V. Reshetov, G. V. Khamidulin, S. S. Shilin, V. I. Torshin, M. G. Kostyaeva, V. I. Popadyuk, T. Y. Yunusov, P. E. Shmaevsky, K. P. Shalamov, A. D. Kupryakova, E. S. Doroginskaya & A. D. Sedelnikova. (2021) Influence of Surgical Trauma in the Nasal Cavity on the Expression of p53 Protein in the Hippocampus of Rats. Doklady Biochemistry and Biophysics 497:1, pages 99-103.
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Maria E. Ramos-Araque, Cristina Rodriguez, Rebeca Vecino, Elisa Cortijo Garcia, Mercedes de Lera Alfonso, Mercedes Sanchez Barba, Laura Colàs-Campàs, Francisco Purroy, Juan F. Arenillas, Angeles Almeida & Maria Delgado-Esteban. (2018) The Neuronal Ischemic Tolerance Is Conditioned by the Tp53 Arg72Pro Polymorphism. Translational Stroke Research 10:2, pages 204-215.
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Shishir Kumar Gupta, Ravi Kumar Gandham, A. P. Sahoo & A. K. Tiwari. (2014) Viral genes as oncolytic agents for cancer therapy. Cellular and Molecular Life Sciences 72:6, pages 1073-1094.
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Marzia Leotta, Lavinia Biamonte, Lavinia Raimondi, Domenica Ronchetti, Maria Teresa Di Martino, Cirino Botta, Emanuela Leone, Maria Rita Pitari, Antonino Neri, Antonio Giordano, Pierosandro Tagliaferri, Pierfrancesco Tassone & Nicola Amodio. (2014) A p53-Dependent Tumor Suppressor Network Is Induced by Selective miR-125a-5p Inhibition in Multiple Myeloma Cells. Journal of Cellular Physiology 229:12, pages 2106-2116.
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Wiem Chaabane, Artur Cieślar-Pobuda, Mohamed El-Gazzah, Mayur V. Jain, Joanna Rzeszowska-Wolny, Mehrdad Rafat, Joerg Stetefeld, Saeid Ghavami & Marek J. Łos. (2014) Human-Gyrovirus-Apoptin Triggers Mitochondrial Death Pathway—Nur77 is Required for Apoptosis Triggering. Neoplasia 16:9, pages 679-693.
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Karina J. Matissek, Abood Okal, Mohanad Mossalam & Carol S. Lim. (2014) Delivery of a Monomeric p53 Subdomain with Mitochondrial Targeting Signals from Pro-Apoptotic Bak or Bax. Pharmaceutical Research 31:9, pages 2503-2515.
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Katharina Zirngibl & Ute M. Moll. 2014. Necrotic Cell Death. Necrotic Cell Death 195 209 .
Patricia HoyerSakhila Banu. 2013. Ovarian Toxicology, Second Edition. Ovarian Toxicology, Second Edition 191 228 .
Michelle Martinez-Rivera & Zahid H. Siddik. (2012) Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53. Biochemical Pharmacology 83:8, pages 1049-1062.
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Irina I. Suvorova, Natalia V. Katolikova & Valery A. Pospelov. 2012. International Review of Cell and Molecular Biology Volume 299. International Review of Cell and Molecular Biology Volume 299 161 198 .
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Sakhila K. Banu, Jone A. Stanley, JeHoon Lee, Sam D. Stephen, Joe A. Arosh, Patricia B. Hoyer & Robert C. Burghardt. (2011) Hexavalent chromium-induced apoptosis of granulosa cells involves selective sub-cellular translocation of Bcl-2 members, ERK1/2 and p53. Toxicology and Applied Pharmacology 251:3, pages 253-266.
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Yuguang Zhao, Yi Tan, Junying Dai, Bing Li, Luping Guo, Jiuwei Cui, Guanjun Wang, Xue Shi, Xiang Zhang, Nicholas Mellen, Wei Li & Lu Cai. (2011) Exacerbation of diabetes-induced testicular apoptosis by zinc deficiency is most likely associated with oxidative stress, p38 MAPK activation, and p53 activation in mice. Toxicology Letters 200:1-2, pages 100-106.
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Diane L.N. Trinh, Adam N. Elwi & Sung-Woo Kim. (2010) Direct interaction between p53 and Tid1 proteins affects p53 mitochondrial localization and apoptosis. Oncotarget 1:6, pages 396-404.
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Emma Hernlund, Ozgur Kutuk, Huveyda Basaga, Stig Linder, Theocharis Panaretakis & Maria Shoshan. (2009) Cisplatin-induced nitrosylation of p53 prevents its mitochondrial translocation. Free Radical Biology and Medicine 46:12, pages 1607-1613.
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Sonja Wolff, Susan Erster, Gustavo Palacios & Ute M Moll. (2008) p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity. Cell Research 18:7, pages 733-744.
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Jian-Wei Fei & Ethel-Michele de Villiers. (2008) Degradation of HPV20E6 by p53: ΔNp63α and mutant p53R248W protect the wild type p53 mediated caspase-degradation. International Journal of Cancer 123:1, pages 108-116.
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Kurt Bommert, Ralf C. Bargou & Thorsten Stühmer. (2006) Signalling and survival pathways in multiple myeloma. European Journal of Cancer 42:11, pages 1574-1580.
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J. F. Charlot, M. Nicolier, J. L. Prétet & C. Mougin. (2006) Modulation of p53 transcriptional activity by PRIMA-1 and Pifithrin-α on staurosporine-induced apoptosis of wild-type and mutated p53 epithelial cells. Apoptosis 11:5, pages 813-827.
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Takahiko Kobayashi, Ting Wang, Masaji Maezawa, Masanobu Kobayashi, Shunsuke Ohnishi, Kazuteru Hatanaka, Shuhei Hige, Yuichi Shimizu, Mototsugu Kato, Masahiro Asaka, Junji Tanaka, Masahiro Imamura, Kiminori Hasegawa, Yoshiyuki Tanaka & Rainer K. Brachmann. (2006) Overexpression of the Oncoprotein Prothymosin α Triggers a p53 Response that Involves p53 Acetylation. Cancer Research 66:6, pages 3137-3144.
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Nathan P. Gomes, Glen Bjerke, Briardo Llorente, Stephanie A. Szostek, Beverly M. Emerson & Joaquin M. Espinosa. (2006) Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program. Genes & Development 20:5, pages 601-612.
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Ira SKVORTSOVA, Sergej SKVORTSOV, Bela-Andre POPPER, Alfred HAIDENBERGER, Maria SAURER, Andreas R. GUNKEL, Heinz ZWIERZINA & Peter LUKAS. (2006) Rituximab Enhances Radiation-Triggered Apoptosis in Non-Hodgkin's Lymphoma Cells Via Caspase-dependent and - Independent Mechanisms. Journal of Radiation Research 47:2, pages 183-196.
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Elena Lomonosova, T Subramanian & G Chinnadurai. (2005) Mitochondrial localization of p53 during adenovirus infection and regulation of its activity by E1B-19K. Oncogene 24:45, pages 6796-6808.
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Subbareddy Maddika, Evan P. Booy, Dina Johar, Spencer B. Gibson, Saeid Ghavami & Marek Los. (2005) Cancer-specific toxicity of apoptin is independent of death receptors but involves the loss of mitochondrial membrane potential and the release of mitochondrial cell-death mediators by a Nur77-dependent pathway. Journal of Cell Science 118:19, pages 4485-4493.
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