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Elevated Levels of Thymidylate Synthase Linked to Neoplastic Transformation of Mammalian Cells

Pages 1003-1005 | Published online: 21 May 2004

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G. Ravacci, J. R. Santos & D. L. Waitzberg. 2019. Nutrition and Cancer Prevention. Nutrition and Cancer Prevention 128 146 .
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Eric Ciappio & Joel Mason. 2009. Folate in Health and Disease, Second Edition. Folate in Health and Disease, Second Edition 235 262 .
Mats Ljungman. (2009) Targeting the DNA Damage Response in Cancer. Chemical Reviews 109:7, pages 2929-2950.
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Zhe Zhao, Yan Shi, Fei Ke, Sun Wei, Jianfang Gui & Qiya Zhang. (2008) Constitutive expression of thymidylate synthase from LCDV-C induces a transformed phenotype in fish cells. Virology 372:1, pages 118-126.
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Javier A. Menendez & Ruth Lupu. (2007) Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis. Nature Reviews Cancer 7:10, pages 763-777.
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Joel B. Mason, Aaron Dickstein, Paul F. Jacques, Paul Haggarty, Jacob Selhub, Gerard Dallal & Irwin H. Rosenberg. (2007) A Temporal Association between Folic Acid Fortification and an Increase in Colorectal Cancer Rates May Be Illuminating Important Biological Principles: A Hypothesis. Cancer Epidemiology, Biomarkers & Prevention 16:7, pages 1325-1329.
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