614
Views
66
CrossRef citations to date
0
Altmetric
Report

Novel anticancer compounds induce apoptosis in melanoma cells

Pages 1851-1855 | Published online: 16 Jun 2008

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (4)

Lizhu Jiang, Peng Wang & Hongyan Chen. (2014) Overexpression of FOXM1 is associated with metastases of nasopharyngeal carcinoma. Upsala Journal of Medical Sciences 119:4, pages 324-332.
Read now
Andrei L. Gartel. (2011) Thiostrepton, proteasome inhibitors and FOXM1. Cell Cycle 10:24, pages 4341-4342.
Read now
Bulbul Pandit, Uppoor G. Bhat & Andrei L. Gartel. (2011) Proteasome inhibitory activity of thiazole antibiotics . Cancer Biology & Therapy 11:1, pages 43-47.
Read now
Andrei L Gartel. (2010) A new target for proteasome inhibitors: FoxM1. Expert Opinion on Investigational Drugs 19:2, pages 235-242.
Read now

Articles from other publishers (62)

Sirinun Pisamai, Steven W. Edwards, Chew Weng Cheng, Phannita Chaivichit, Mokhapoom Sooksiri, Sujittra Yanakam, Sattabongkoch Maneewong & Gunnaporn Suriyaphol. (2023) Tissue transcriptome profiling and pathway analyses revealed novel potential biomarkers in the tumor progression of canine oral melanoma. Research in Veterinary Science 165, pages 105036.
Crossref
Sanjeev Raghuwanshi & Andrei L. Gartel. (2023) Small-molecule inhibitors targeting FOXM1: Current challenges and future perspectives in cancer treatments. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, pages 189015.
Crossref
Ellen Voigt & Dawn E. Quelle. (2023) FOXM1, MEK, and CDK4/6: New Targets for Malignant Peripheral Nerve Sheath Tumor Therapy. International Journal of Molecular Sciences 24:17, pages 13596.
Crossref
Chayanid Ongpipattanakul, Emily K. Desormeaux, Adam DiCaprio, Wilfred A. van der Donk, Douglas A. Mitchell & Satish K. Nair. (2022) Mechanism of Action of Ribosomally Synthesized and Post-Translationally Modified Peptides. Chemical Reviews 122:18, pages 14722-14814.
Crossref
Galal H. Elgemeie & Reham A. Mohamed-Ezzat. 2022. New Strategies Targeting Cancer Metabolism. New Strategies Targeting Cancer Metabolism 303 392 .
Abdullahi Bello Umar, Adamu Uzairu, Gideon Adamu Shallangwa & Sani Uba. (2021) Ligand-based drug design and molecular docking simulation studies of some novel anticancer compounds on MALME-3M melanoma cell line. Egyptian Journal of Medical Human Genetics 22:1.
Crossref
Dhanya Kalathil, Samu John & Asha S. Nair. (2021) FOXM1 and Cancer: Faulty Cellular Signaling Derails Homeostasis. Frontiers in Oncology 10.
Crossref
Grace E. Hubbell & Jetze J. Tepe. (2020) Natural product scaffolds as inspiration for the design and synthesis of 20S human proteasome inhibitors. RSC Chemical Biology 1:5, pages 305-332.
Crossref
Kelly E. Bird, Christian Xander, Sebastian Murcia, Alan A. Schmalstig, Xianxi Wang, Michael J. Emanuele, Miriam Braunstein & Albert A. Bowers. (2020) Thiopeptides Induce Proteasome-Independent Activation of Cellular Mitophagy. ACS Chemical Biology 15:8, pages 2164-2174.
Crossref
Maryam Zamanian-Daryoush, Daniel J. Lindner, Jennifer Buffa, Banu Gopalan, Jie Na, Stanley L. Hazen & Joseph A. DiDonato. (2020) Apolipoprotein A-I anti-tumor activity targets cancer cell metabolism. Oncotarget 11:19, pages 1777-1796.
Crossref
Mitchell P. Christy, Trevor Johnson, Clare D. McNerlin, John Woodard, Andrew T. Nelson, Bryant Lim, Tiffany L. Hamilton, Kaitlyn M. Freiberg & Dionicio Siegel. (2020) Total Synthesis of Micrococcin P1 through Scalable Thiazole Forming Reactions of Cysteine Derivatives and Nitriles. Organic Letters 22:6, pages 2365-2370.
Crossref
Yue Sheng, Chunjie Yu, Yin Liu, Chao Hu, Rui Ma, Xinyan Lu, Peng Ji, Jianjun Chen, Benjamin Mizukawa, Yong Huang, Jonathan D. Licht & Zhijian Qian. (2020) FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML. Nature Communications 11:1.
Crossref
Kelly E. Bird & Albert A. Bowers. 2020. Comprehensive Natural Products III. Comprehensive Natural Products III 166 192 .
Xiaoqi Shen, Muhammad Mustafa, Yanyang Chen, Yingying Cao & Jiangtao Gao. (2019) Natural thiopeptides as a privileged scaffold for drug discovery and therapeutic development. Medicinal Chemistry Research 28:8, pages 1063-1098.
Crossref
Lucile Hoch, Sara F. Henriques, Celine Bruge, Justine Marsolier, Manon Benabides, Nathalie Bourg, Johana Tournois, Gurvan Mahé, Lise Morizur, Margot Jarrige, Anne Bigot, Isabelle Richard & Xavier Nissan. (2019) Identification of thiostrepton as a pharmacological approach to rescue misfolded alpha-sarcoglycan mutant proteins from degradation. Scientific Reports 9:1.
Crossref
Asaf A. Qureshi, Eleanor G. Zuvanich, Dilshad A. Khan, Shahida Mushtaq, Neerupma Silswal & Nilofer Qureshi. (2018) Proteasome inhibitors modulate anticancer and anti-proliferative properties via NF-kB signaling, and ubiquitin-proteasome pathways in cancer cell lines of different organs. Lipids in Health and Disease 17:1.
Crossref
Jingbo Dai, Qiyuan Zhou, Haiyang Tang, Tianji Chen, Jing Li, Pradip Raychaudhuri, Jason X.-J. Yuan & Guofei Zhou. (2018) Smooth muscle cell-specific FoxM1 controls hypoxia-induced pulmonary hypertension. Cellular Signalling 51, pages 119-129.
Crossref
Vivienne Lee, Lucinda McRobb, Vaughan Moutrie, Estavam Santos & Timothy Siu. (2018) Effects of FOXM1 inhibition and ionizing radiation on melanoma cells. Oncology Letters.
Crossref
Akihiro Watari, Miki Kodaka, Koji Matsuhisa, Yuta Sakamoto, Kota Hisaie, Norihito Kawashita, Tatsuya Takagi, Yoshiaki Yamagishi, Hidehiko Suzuki, Hirofumi Tsujino, Kiyohito Yagi & Masuo Kondoh. (2017) Identification of claudin-4 binder that attenuates tight junction barrier function by TR-FRET-based screening assay. Scientific Reports 7:1.
Crossref
Barbara Fontanals-Cirera, Dan Hasson, Chiara Vardabasso, Raffaella Di Micco, Praveen Agrawal, Asif Chowdhury, Madeleine Gantz, Ana de Pablos-Aragoneses, Ari Morgenstern, Pamela Wu, Dan Filipescu, David Valle-Garcia, Farbod Darvishian, Jae-Seok Roe, Michael A. Davies, Christopher R. Vakoc, Eva Hernando & Emily Bernstein. (2017) Harnessing BET Inhibitor Sensitivity Reveals AMIGO2 as a Melanoma Survival Gene. Molecular Cell 68:4, pages 731-744.e9.
Crossref
Pavla Perlíková & Michal Hocek. (2017) Pyrrolo[2,3‐ d ]pyrimidine (7‐deazapurine) as a privileged scaffold in design of antitumor and antiviral nucleosides . Medicinal Research Reviews 37:6, pages 1429-1460.
Crossref
Brandon J. Burkhart, Christopher J. Schwalen, Greg Mann, James H. Naismith & Douglas A. Mitchell. (2017) YcaO-Dependent Posttranslational Amide Activation: Biosynthesis, Structure, and Function. Chemical Reviews 117:8, pages 5389-5456.
Crossref
Hatem K. Amin, Amr M. El-Araby, Sameh Eid, Tamer Nasr, Samir Bondock, Ola Leheta & Moustafa E. Dawoud. (2017) A Thiazole Analogue Exhibits an Anti-Proliferative Effect in Different Human Carcinoma Cell Lines and Its Mechanism Based on Molecular Modeling. Advances in Biological Chemistry 07:01, pages 76-87.
Crossref
Judith Hagenbuchner & Michael J. Ausserlechner. (2016) Targeting transcription factors by small compounds—Current strategies and future implications. Biochemical Pharmacology 107, pages 1-13.
Crossref
Marianna Halasi, Renáta Váraljai, Elizaveta Benevolenskaya & Andrei L. Gartel. (2016) A Novel Function of Molecular Chaperone HSP70. Journal of Biological Chemistry 291:1, pages 142-148.
Crossref
Panpan Duan, Qingfei Zheng, Zhi Lin, Shoufeng Wang, Dandan Chen & Wen Liu. (2016) Molecular engineering of thiostrepton via single “base”-based mutagenesis to generate side ring-derived variants. Organic Chemistry Frontiers 3:10, pages 1254-1258.
Crossref
Azusa Miyashita, Satoshi Fukushima, Satoshi Nakahara, Junji Yamashita, Aki Tokuzumi, Jun Aoi, Asako Ichihara, Hisashi Kanemaru, Masatoshi Jinnin & Hironobu Ihn. (2015) Investigation of FOXM1 as a Potential New Target for Melanoma. PLOS ONE 10:12, pages e0144241.
Crossref
Xuedan Guo, Aiping Liu, Hongxia Hua, Huifen Lu, Dandan Zhang, Yina Lin, Qing Sun, Xue Zhu, Guoxin Yan & Fan Zhao. (2015) Siomycin A Induces Apoptosis in Human Lung Adenocarcinoma A549 Cells by Suppressing the Expression of FoxM1. Natural Product Communications 10:9, pages 1934578X1501000.
Crossref
Cristinel Sandu, Nagaranjan Chandramouli, Joseph Fraser Glickman, Henrik Molina, Chueh-Ling Kuo, Nikolay Kukushkin, Alfred L. Goldberg & Hermann Steller. (2015) Thiostrepton interacts covalently with Rpt subunits of the 19S proteasome and proteasome substrates. Journal of Cellular and Molecular Medicine 19:9, pages 2181-2192.
Crossref
S-Y Ju, C-YF Huang, W-C Huang & Y Su. (2015) Identification of thiostrepton as a novel therapeutic agent that targets human colon cancer stem cells. Cell Death & Disease 6:7, pages e1801-e1801.
Crossref
Maike Buchner, Eugene Park, Huimin Geng, Lars Klemm, Johanna Flach, Emmanuelle Passegué, Hilde Schjerven, Ari Melnick, Elisabeth Paietta, Dragana Kopanja, Pradip Raychaudhuri & Markus Müschen. (2015) Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia. Nature Communications 6:1.
Crossref
Özlem Tüfekçi, Melis Kartal Yandım, Hale Ören, Gülersu İrken & Yusuf Baran. (2015) Targeting FoxM1 transcription factor in T-cell acute lymphoblastic leukemia cell line. Leukemia Research 39:3, pages 342-347.
Crossref
Y Zha, Y Xia, J Ding, J-H Choi, L Yang, Z Dong, C Yan, S Huang & H-F Ding. (2014) MEIS2 is essential for neuroblastoma cell survival and proliferation by transcriptional control of M-phase progression. Cell Death & Disease 5:9, pages e1417-e1417.
Crossref
Xiangbing Meng, Eric Devor, Shujie Yang, Brandon Schickling & Kimberly Leslie. (2014) Role of MTDH, FOXM1 and microRNAs in Drug Resistance in Hepatocellular Carcinoma. Diseases 2:3, pages 209-225.
Crossref
Bingpeng Chen, Jingjing Liu, Dankai Wu, Yanguo Qin, Chuangang Peng, Chen Li & Jincheng Wang. (2014) Gene silencing of NOB1 by lentivirus suppresses growth and migration of human osteosarcoma cells. Molecular Medicine Reports.
Crossref
Malgorzata Sztiller-Sikorska, Kamila Koprowska, Kinga Majchrzak, Mariusz Hartman & Malgorzata Czyz. (2014) Natural Compounds' Activity against Cancer Stem-Like or Fast-Cycling Melanoma Cells. PLoS ONE 9:3, pages e90783.
Crossref
Xavier Just-Baringo, Fernando Albericio & Mercedes Álvarez. (2014) Thiopeptide Antibiotics: Retrospective and Recent Advances. Marine Drugs 12:1, pages 317-351.
Crossref
Andrei L. Gartel. (2014) Suppression of the Oncogenic Transcription Factor FOXM1 by Proteasome Inhibitors. Scientifica 2014, pages 1-5.
Crossref
Cristinel Sandu, Armand G. Ngounou Wetie, Costel C. Darie & Hermann Steller. 2014. Advancements of Mass Spectrometry in Biomedical Research. Advancements of Mass Spectrometry in Biomedical Research 443 451 .
Marianna Halasi, Bulbul Pandit, Ming Wang, Veronique Nogueira, Nissim Hay & Andrei L. Gartel. (2013) Combination of Oxidative Stress and FOXM1 Inhibitors Induces Apoptosis in Cancer Cells and Inhibits Xenograft Tumor Growth. The American Journal of Pathology 183:1, pages 257-265.
Crossref
Marianna Halasi & Andrei L. Gartel. (2013) Targeting FOXM1 in cancer. Biochemical Pharmacology 85:5, pages 644-652.
Crossref
Inken Wierstra. 2013. 191 419 .
Albert A. Bowers. (2012) Biochemical and biosynthetic preparation of natural product-like cyclic peptide libraries. MedChemComm 3:8, pages 905-915.
Crossref
Shuxi Qiao, Sarah D. Lamore, Christopher M. Cabello, Jessica L. Lesson, José L. Muñoz-Rodriguez & Georg T. Wondrak. (2012) Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytes. Biochemical Pharmacology 83:9, pages 1229-1240.
Crossref
Lian Duan, Shoufeng Wang, Rijing Liao & Wen Liu. (2012) Insights into Quinaldic Acid Moiety Formation in Thiostrepton Biosynthesis Facilitating Fluorinated Thiopeptide Generation. Chemistry & Biology 19:4, pages 443-448.
Crossref
Marianna Halasi & Andrei L. Gartel. (2012) Suppression of FOXM1 Sensitizes Human Cancer Cells to Cell Death Induced by DNA-Damage. PLoS ONE 7:2, pages e31761.
Crossref
Ming Wang & Andrei L. Gartel. (2011) Micelle-Encapsulated Thiostrepton as an Effective Nanomedicine for Inhibiting Tumor Growth and for Suppressing FOXM1 in Human Xenografts. Molecular Cancer Therapeutics 10:12, pages 2287-2297.
Crossref
Uppoor G. Bhat, Ramasamy Jagadeeswaran, Marianna Halasi & Andrei L. Gartel. (2011) Nucleophosmin Interacts with FOXM1 and Modulates the Level and Localization of FOXM1 in Human Cancer Cells. Journal of Biological Chemistry 286:48, pages 41425-41433.
Crossref
Christine M. Stellrecht & Lisa S. Chen. (2011) Transcription Inhibition as a Therapeutic Target for Cancer. Cancers 3:4, pages 4170-4190.
Crossref
Nagaratna S. Hegde, Deborah A. Sanders, Raphaël Rodriguez & Shankar Balasubramanian. (2011) The transcription factor FOXM1 is a cellular target of the natural product thiostrepton. Nature Chemistry 3:9, pages 725-731.
Crossref
Gabriel T. M. Lok, David W. Chan, Vincent W. S. Liu, Winnie W. Y. Hui, Thomas H. Y. Leung, K. M. Yao & Hextan Y. S. Ngan. (2011) Aberrant Activation of ERK/FOXM1 Signaling Cascade Triggers the Cell Migration/Invasion in Ovarian Cancer Cells. PLoS ONE 6:8, pages e23790.
Crossref
I. Nakano, K. Joshi, K. Visnyei, B. Hu, M. Watanabe, D. Lam, E. Wexler, K. Saigusa, Y. Nakamura, D. R. Laks, P. S. Mischel, M. Viapiano & H. I. Kornblum. (2011) Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway. Neuro-Oncology 13:6, pages 622-634.
Crossref
Bulbul Pandit & Andrei L. Gartel. (2011) Thiazole Antibiotic Thiostrepton Synergize with Bortezomib to Induce Apoptosis in Cancer Cells. PLoS ONE 6:2, pages e17110.
Crossref
D. R. Littler, M. Alvarez-Fernandez, A. Stein, R. G. Hibbert, T. Heidebrecht, P. Aloy, R. H. Medema & A. Perrakis. (2010) Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence. Nucleic Acids Research 38:13, pages 4527-4538.
Crossref
Uppoor G. Bhat, Bulbul Pandit & Andrei L. Gartel. (2010) ARC Synergizes with ABT-737 to Induce Apoptosis in Human Cancer Cells. Molecular Cancer Therapeutics 9:6, pages 1688-1696.
Crossref
Bulbul Pandit & Andrei L. Gartel. (2010) New potential anti‐cancer agents synergize with bortezomib and ABT‐737 against prostate cancer. The Prostate 70:8, pages 825-833.
Crossref
Sebastian Schoof, Gabriele Pradel, Makoah N. Aminake, Bernhard Ellinger, Sascha Baumann, Marco Potowski, Yousef Najajreh, Marc Kirschner & Hans‐Dieter Arndt. (2010) Antiplasmodial Thiostrepton Derivatives: Proteasome Inhibitors with a Dual Mode of Action. Angewandte Chemie International Edition 49:19, pages 3317-3321.
Crossref
Sebastian Schoof, Gabriele Pradel, Makoah N. Aminake, Bernhard Ellinger, Sascha Baumann, Marco Potowski, Yousef Najajreh, Marc Kirschner & Hans‐Dieter Arndt. (2010) Antiplasmodiale Thiostreptonderivate – Proteasominhibitoren mit einem dualen Wirkmechanismus. Angewandte Chemie 122:19, pages 3389-3393.
Crossref
U G Bhat & A L Gartel. (2010) Nucleoside analog ARC targets Mcl-1 to induce apoptosis in leukemia cells. Leukemia 24:4, pages 851-855.
Crossref
Uppoor G. Bhat, Marianna Halasi & Andrei L. Gartel. (2009) FoxM1 Is a General Target for Proteasome Inhibitors. PLoS ONE 4:8, pages e6593.
Crossref
Uppoor G. Bhat, Marianna Halasi & Andrei L. Gartel. (2009) Thiazole Antibiotics Target FoxM1 and Induce Apoptosis in Human Cancer Cells. PLoS ONE 4:5, pages e5592.
Crossref
Sebastian Schoof, Sascha Baumann, Bernhard Ellinger & Hans-Dieter Arndt. (2009) A Fluorescent Probe for the 70 S-Ribosomal GTPase-Associated Center. ChemBioChem 10:2, pages 242-245.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.