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APC/CCdc20 targets E2F1 for degradation in prometaphase

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Pages 3956-3964 | Published online: 01 Oct 2010

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Somsubhra Nath, Abhishek Chowdhury, Sanjib Dey, Anirban Roychoudhury, Abira Ganguly, Dibyendu Bhattacharyya & Susanta Roychoudhury. (2015) Deregulation of Rb-E2F1 Axis Causes Chromosomal Instability by Engaging the Transactivation Function of Cdc20–Anaphase-Promoting Complex/Cyclosome. Molecular and Cellular Biology 35:2, pages 356-369.
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Dipali Date, Amy Burrows, Monica Venere, Mark Jackson & Matthew Summers. (2013) Coordinated regulation of p31Comet and Mad2 expression is required for cellular proliferation. Cell Cycle 12:24, pages 3824-3832.
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Meital Cohen, Manuela Vecsler, Arthur Liberzon, Meirav Noach, Eitan Zlotorynski & Amit Tzur. (2013) Unbiased transcriptome signature of in vivo cell proliferation reveals pro- and antiproliferative gene networks. Cell Cycle 12:18, pages 2992-3000.
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Nitin Raj, Liang Zhang, Yiliang Wei, David N. Arnosti & R. William Henry. (2012) Rbf1 degron dysfunction enhances cellular DNA replication. Cell Cycle 11:20, pages 3731-3738.
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Articles from other publishers (35)

Siming Chen, Zhiwen He, Tianchen Peng, Fenfang Zhou, Gang Wang, Kaiyu Qian, Lingao Ju, Yu Xiao & Xinghuan Wang. (2021) PRR11 promotes ccRCC tumorigenesis by regulating E2F1 stability. JCI Insight 6:19.
Crossref
David R. Tong, Wen Zhou, Chen Katz, Kausik Regunath, Divya Venkatesh, Chinyere Ihuegbu, James J. Manfredi, Oleg Laptenko & Carol Prives. (2021) p53 Frameshift Mutations Couple Loss-of-Function with Unique Neomorphic Activities. Molecular Cancer Research 19:9, pages 1522-1533.
Crossref
Tatyana Bodrug, Kaeli A. Welsh, Megan Hinkle, Michael J. Emanuele & Nicholas G. Brown. (2021) Intricate Regulatory Mechanisms of the Anaphase-Promoting Complex/Cyclosome and Its Role in Chromatin Regulation. Frontiers in Cell and Developmental Biology 9.
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Sebastian Allmann, Laura Mayer, Jessika Olma, Bernd Kaina, Thomas G Hofmann, Maja T Tomicic & Markus Christmann. (2020) Benzo[a]pyrene represses DNA repair through altered E2F1/E2F4 function marking an early event in DNA damage-induced cellular senescence. Nucleic Acids Research 48:21, pages 12085-12101.
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Michael J. Emanuele, Taylor P. Enrico, Ryan D. Mouery, Danit Wasserman, Sapir Nachum & Amit Tzur. (2020) Complex Cartography: Regulation of E2F Transcription Factors by Cyclin F and Ubiquitin. Trends in Cell Biology 30:8, pages 640-652.
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Lindsey N. Kent & Gustavo Leone. (2019) The broken cycle: E2F dysfunction in cancer. Nature Reviews Cancer 19:6, pages 326-338.
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Linda Clijsters, Claire Hoencamp, Jorg J.A. Calis, Antonio Marzio, Shanna M. Handgraaf, Maria C. Cuitino, Brad R. Rosenberg, Gustavo Leone & Michele Pagano. (2019) Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs. Molecular Cell 74:6, pages 1264-1277.e7.
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Jitender S. Bisht, Miroslav Tomschik & Jesse C. Gatlin. (2019) Induction of a Spindle-Assembly-Competent M Phase in Xenopus Egg Extracts. Current Biology 29:8, pages 1273-1285.e5.
Crossref
Xiao Fang, Hua Yin, Hanqing Zhang, Fan Wu, Yin Liu, Yi Fu, Duonan Yu & Liang Zong. (2019) p53 mediates hydroxyurea resistance in aneuploid cells of colon cancer. Experimental Cell Research 376:1, pages 39-48.
Crossref
Jan Inge Øvrebø & Bruce A. Edgar. (2018) Polyploidy in tissue homeostasis and regeneration. Development 145:14.
Crossref
Wafik Zaky, Christa Manton, Claudia P. Miller, Soumen Khatua, Vidya Gopalakrishnan & Joya Chandra. (2017) The ubiquitin-proteasome pathway in adult and pediatric brain tumors: biological insights and therapeutic opportunities. Cancer and Metastasis Reviews 36:4, pages 617-633.
Crossref
Laurence Dubrez. (2017) Regulation of E2F1 Transcription Factor by Ubiquitin Conjugation. International Journal of Molecular Sciences 18:10, pages 2188.
Crossref
Miyoung Lee, Yainyrette Rivera-Rivera, Carlos S. Moreno & Harold I. Saavedra. (2017) The E2F activators control multiple mitotic regulators and maintain genomic integrity through Sgo1 and BubR1. Oncotarget 8:44, pages 77649-77672.
Crossref
Valérie Glorian, Jennifer Allègre, Jean Berthelet, Baptiste Dumetier, Pierre-Marie Boutanquoi, Nathalie Droin, Cémile Kayaci, Jessy Cartier, Simon Gemble, Guillaume Marcion, Daniel Gonzalez, Romain Boidot, Carmen Garrido, Olivier Michaud, Eric Solary & Laurence Dubrez. (2017) DNA damage and S phase-dependent E2F1 stabilization requires the cIAP1 E3-ubiquitin ligase and is associated with K63-poly-ubiquitination on lysine 161/164 residues. Cell Death & Disease 8:5, pages e2816-e2816.
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Randeep K. Singh & Lina Dagnino. (2016) CDH1 regulates E2F1 degradation in response to differentiation signals in keratinocytes. Oncotarget 8:3, pages 4977-4993.
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Zhaojia Gao, Run Shi, Kai Yuan & Yong Wang. (2016) Expression and prognostic value of E2F activators in NSCLC and subtypes: a research based on bioinformatics analysis. Tumor Biology 37:11, pages 14979-14987.
Crossref
Pauline Traynard, Adrien Fauré, François Fages & Denis Thieffry. (2016) Logical model specification aided by model-checking techniques: application to the mammalian cell cycle regulation. Bioinformatics 32:17, pages i772-i780.
Crossref
Panagiotis Galanos, Konstantinos Vougas, David Walter, Alexander Polyzos, Apolinar Maya-Mendoza, Emma J. Haagensen, Antonis Kokkalis, Fani-Marlen Roumelioti, Sarantis Gagos, Maria Tzetis, Begoña Canovas, Ana Igea, Akshay K. Ahuja, Ralph Zellweger, Sofia Havaki, Emanuel Kanavakis, Dimitris Kletsas, Igor B. Roninson, Spiros D. Garbis, Massimo Lopes, Angel Nebreda, Dimitris Thanos, J. Julian Blow, Paul Townsend, Claus Storgaard Sørensen, Jiri Bartek & Vassilis G. Gorgoulis. (2016) Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing. Nature Cell Biology 18:7, pages 777-789.
Crossref
Michiel Boekhout, Ruixue Yuan, Annelotte P Wondergem, Hendrika A Segeren, Elsbeth A van Liere, Nesibu Awol, Imke Jansen, Rob MF Wolthuis, Alain de Bruin & Bart Westendorp. (2016) Feedback regulation between atypical E2Fs and APC / C C dh1 coordinates cell cycle progression . EMBO reports 17:3, pages 414-427.
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Bin Li, Wen Wen Xu, Xin Yuan Guan, Yan Ru Qin, Simon Law, Nikki Pui Yue Lee, Kin Tak Chan, Pui Ying Tam, Yuk Yin Li, Kwok Wah Chan, Hiu Fung Yuen, Sai Wah Tsao, Qing Yu He & Annie L.M. Cheung. (2016) Competitive Binding Between Id1 and E2F1 to Cdc20 Regulates E2F1 Degradation and Thymidylate Synthase Expression to Promote Esophageal Cancer Chemoresistance. Clinical Cancer Research 22:5, pages 1243-1255.
Crossref
Ingrid Thurlings & Alain de Bruin. 2016. Cell Cycle Oscillators. Cell Cycle Oscillators 71 88 .
Boshi Wang, Aihui Ma, Li Zhang, Wei-Lin Jin, Yu Qian, Guiqin Xu, Bijun Qiu, Zhaojuan Yang, Yun Liu, Qiang Xia & Yongzhong Liu. (2015) POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation. Nature Communications 6:1.
Crossref
Christina S. Mahanic, Varija Budhavarapu, Joshua D. Graves, Gang Li & Weei-Chin Lin. (2015) Regulation of E2 Promoter Binding Factor 1 (E2F1) Transcriptional Activity through a Deubiquitinating Enzyme, UCH37. Journal of Biological Chemistry 290:44, pages 26508-26522.
Crossref
Satyaki Sengupta & R. William Henry. (2015) Regulation of the retinoblastoma–E2F pathway by the ubiquitin–proteasome system. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1849:10, pages 1289-1297.
Crossref
S-M Hede, V Savov, H Weishaupt, O Sangfelt & F J Swartling. (2013) Oncoprotein stabilization in brain tumors. Oncogene 33:39, pages 4709-4721.
Crossref
Sarah G. Hainline, Jamie L. RickmyreLeif R. Neitzel, Laura A. Lee & Ethan Lee. (2014) The Drosophila MCPH1-B isoform is a substrate of the APCCdh1 E3 ubiquitin ligase complex . Biology Open 3:7, pages 669-676.
Crossref
Michael C. Weis, Jayant Avva, James W. Jacobberger & Sree N. Sreenath. (2014) A Data-Driven, Mathematical Model of Mammalian Cell Cycle Regulation. PLoS ONE 9:5, pages e97130.
Crossref
Jing-Lei Liu, Guang-Zhi Zeng, Xiao-Li Liu, Yong-Qiang Liu, Zhong-Guo Hu, Ying Liu, Ning-Hua Tan & Guang-Biao Zhou. (2013) Small compound bigelovin exerts inhibitory effects and triggers proteolysis of E2F1 in multiple myeloma cells. Cancer Science 104:12, pages 1697-1704.
Crossref
Li-Chuan Wu, Zhe-Sheng Wen, Ya-Tao Qiu, Xiao-Qin Chen, Hao-Bin Chen, Ming-Ming Wei, Zi Liu, Sheng Jiang & Guang-Biao Zhou. (2013) Largazole Arrests Cell Cycle at G1 Phase and Triggers Proteasomal Degradation of E2F1 in Lung Cancer Cells. ACS Medicinal Chemistry Letters 4:10, pages 921-926.
Crossref
Lilyn Daftuar, Yan Zhu, Xavier Jacq & Carol Prives. (2013) Ribosomal Proteins RPL37, RPS15 and RPS20 Regulate the Mdm2-p53-MdmX Network. PLoS ONE 8:7, pages e68667.
Crossref
Manickavinayaham Swarnalatha, Anup Kumar Singh & Vijay Kumar. (2013) Promoter occupancy of MLL1 histone methyltransferase seems to specify the proliferative and apoptotic functions of E2F1 in a tumour microenvironment. Journal of Cell Science.
Crossref
James A. McCubrey, Linda S. Steelman, William H. Chappell, Stephen L. Abrams, Richard A. Franklin, Giuseppe Montalto, Melchiorre Cervello, Massimo Libra, Saverio Candido, Grazia Malaponte, Maria C. Mazzarino, Paolo Fagone, Ferdinando Nicoletti, Jörg Bäsecke, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Michele Milella, Agostino Tafuri, Francesca Chiarini, Camilla Evangelisti, Lucio Cocco & Alberto M. Martelli. (2012) Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR Cascade Inhibitors: How Mutations Can Result in Therapy Resistance and How to Overcome Resistance. Oncotarget 3:10, pages 1068-1111.
Crossref
Min Mo, Saleha Shahar, Stephen B. Fleming & Andrew A. Mercer. (2012) How viruses affect the cell cycle through manipulation of the APC/C. Trends in Microbiology 20:9, pages 440-448.
Crossref
Michel V Hadjihannas, Dominic B Bernkopf, Martina Brückner & Jürgen Behrens. (2012) Cell cycle control of Wnt/β‐catenin signalling by conductin/axin2 through CDC20. EMBO reports 13:4, pages 347-354.
Crossref
Abhik Saha, Jie Lu, Lise Morizur, Santosh K. Upadhyay, Mahadesh Prasad AJ & Erle S. Robertson. (2012) E2F1 Mediated Apoptosis Induced by the DNA Damage Response Is Blocked by EBV Nuclear Antigen 3C in Lymphoblastoid Cells. PLoS Pathogens 8:3, pages e1002573.
Crossref

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