Advanced search
Publication Cover
Channels Volume 6, 2012 - Issue 5
Submit an article Journal homepage
1,687
Views
28
CrossRef citations to date
0
Altmetric
Review

The roles of G proteins in the activation of TRPC4 and TRPC5 transient receptor potential channels

Hana Kim Department of Physiology; Seoul National University College of Medicine; Seoul, Republic of Korea
,
Jinsung Kim Department of Chemistry; Korea Advanced Institute of Science and Technology; Daejeon, Republic of Korea
,
Jae-Pyo Jeon Department of Physiology; Seoul National University College of Medicine; Seoul, Republic of Korea
,
Jongyun Myeong Department of Physiology; Seoul National University College of Medicine; Seoul, Republic of Korea
,
Jinhong Wie Department of Physiology; Seoul National University College of Medicine; Seoul, Republic of Korea
,
Chansik Hong Department of Physiology; Seoul National University College of Medicine; Seoul, Republic of Korea
,
Hyun Jin Kim Department of Physiology; Sungkyunkwan University School of Medicine; Suwon, Republic of Korea
,
Ju-Hong Jeon Department of Physiology; Seoul National University College of Medicine; Seoul, Republic of Korea
&
Insuk So Department of Physiology; Seoul National University College of Medicine; Seoul, Republic of KoreaCorrespondence[email protected]
 show all
Pages 333-343 | Received 23 May 2012, Accepted 20 Jun 2012, Published online: 10 Aug 2012

Citations (28)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (2)

A Martinsen, C Dessy & N Morel. (2014) Regulation of calcium channels in smooth muscle: New insights into the role of myosin light chain kinase. Channels 8:5, pages 402-413.
Read now
Huirong Han & Fan Yi. (2014) New insights into TRP channels. Channels 8:1, pages 13-19.
Read now

Articles from other publishers (26)

Ruslan Bohovyk, Sherif Khedr, Vladislav Levchenko, Mariia Stefanenko, Marharyta Semenikhina, Olha Kravtsova, Elena Isaeva, Aron M. Geurts, Christine A. Klemens, Oleg Palygin & Alexander Staruschenko. (2023) Protease-Activated Receptor 1–Mediated Damage of Podocytes in Diabetic Nephropathy. Diabetes 72:12, pages 1795-1808.
Crossref
Matilde Marini, Mustafa Titiz, Daniel Souza Monteiro de Araújo, Pierangelo Geppetti, Romina Nassini & Francesco De Logu. (2023) TRP Channels in Cancer: Signaling Mechanisms and Translational Approaches. Biomolecules 13:10, pages 1557.
Crossref
Byeongseok Jeong, Young Pyo Song, Ji Yeon Chung, Ki Chul Park, Jinhyeong Kim, Insuk So & Chansik Hong. (2023) Low concentrations of tricyclic antidepressants stimulate TRPC4 channel activity by acting as an opioid receptor ligand. American Journal of Physiology-Cell Physiology 324:6, pages C1295-C1306.
Crossref
Mashoque Ahmad Rather, Andleeb Khan, Lianchun Wang, Sadaf Jahan, Muneeb U. Rehman, Hafiz A. Makeen & Syam Mohan. (2023) TRP channels: Role in neurodegenerative diseases and therapeutic targets. Heliyon 9:6, pages e16910.
Crossref
Byeongseok Jeong, Tae Sik Sung, Dongju Jeon, Kyu Joo Park, Jae Yeoul Jun, Insuk So & Chansik Hong. (2022) Inhibition of TRPC4 channel activity in colonic myocytes by tricyclic antidepressants disrupts colonic motility causing constipation. Journal of Cellular and Molecular Medicine 26:19, pages 4911-4923.
Crossref
Laura Amores-Bonet, Ralf Kleene, Thomas Theis & Melitta Schachner. (2022) Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ into Neurons. International Journal of Molecular Sciences 23:17, pages 10027.
Crossref
Mariia I. Melnyk, Dariia O. Dryn, Lina T. Al Kury, Dmytro O. Dziuba & Alexander V. Zholos. (2020) Suppression of mICAT in Mouse Small Intestinal Myocytes by General Anaesthetic Ketamine and its Recovery by TRPC4 Agonist (-)-englerin A. Frontiers in Pharmacology 11.
Crossref
Chansik Hong, Seo Hwa Choi, Misun Kwak, Byeongseok Jeong, Juyeon Ko, Hyung Joon Park, Seok Choi, Jae Yeoul Jun & Insuk So. (2020) TRPC5 channel instability induced by depalmitoylation protects striatal neurons against oxidative stress in Huntington's disease. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1867:2, pages 118620.
Crossref
Jinsung Kim, Juyeon Ko, Jongyun Myeong, Misun Kwak, Chansik Hong & Insuk So. (2019) TRPC1 as a negative regulator for TRPC4 and TRPC5 channels. Pflügers Archiv - European Journal of Physiology 471:8, pages 1045-1053.
Crossref
Hussein N. Rubaiy. (2019) Treasure troves of pharmacological tools to study transient receptor potential canonical 1/4/5 channels. British Journal of Pharmacology 176:7, pages 832-846.
Crossref
SeungJoo JeongJuyeon KoMinji KimKi Chul ParkEunice Yon June ParkJinsung KimYoungjoo BaikJinhong WieArt E. ChoJu-hong JeonInsuk So. (2019) Englerin A-sensing charged residues for transient receptor potential canonical 5 channel activation. The Korean Journal of Physiology & Pharmacology 23:3, pages 191.
Crossref
Antonio Reboreda, Frederik M. Theissen, Maria J. Valero-Aracama, Alberto Arboit, Mihaela A. Corbu & Motoharu Yoshida. (2018) Do TRPC channels support working memory? Comparing modulations of TRPC channels and working memory through G-protein coupled receptors and neuromodulators. Behavioural Brain Research 354, pages 64-83.
Crossref
Jongyun Myeong, Juyeon Ko, Misun Kwak, Jinsung Kim, Joohan Woo, Kotdaji Ha, Chansik Hong, Dongki Yang, Hyun Jin Kim, Ju-Hong Jeon & Insuk So. (2018) Dual action of the Gαq-PLCβ-PI(4,5)P2 pathway on TRPC1/4 and TRPC1/5 heterotetramers. Scientific Reports 8:1.
Crossref
Dariia Dryn, Jialie Luo, Mariia Melnyk, Alexander Zholos & Hongzhen Hu. (2018) Inhalation anaesthetic isoflurane inhibits the muscarinic cation current and carbachol-induced gastrointestinal smooth muscle contractions. European Journal of Pharmacology 820, pages 39-44.
Crossref
Juyeon KoJongyun MyeongDongki YangInsuk So. (2017) Calcium permeability of transient receptor potential canonical (TRPC) 4 channels measured by TRPC4-GCaMP6s. The Korean Journal of Physiology & Pharmacology 21:1, pages 133.
Crossref
Shengjie Feng. 2017. Transient Receptor Potential Canonical Channels and Brain Diseases. Transient Receptor Potential Canonical Channels and Brain Diseases 9 23 .
Hong-Ni Jiang, Bo Zeng, Gui-Lan Chen, Bin Lai, Shao-Hua Lu & Jie-Ming Qu. (2016) Lipopolysaccharide potentiates endothelin-1-induced proliferation of pulmonary arterial smooth muscle cells by upregulating TRPC channels. Biomedicine & Pharmacotherapy 82, pages 20-27.
Crossref
Ying Xu, Cesare Orlandi, Yan Cao, Shengyan Yang, Chan-Il Choi, Vijayakanth Pagadala, Lutz Birnbaumer, Kirill A. Martemyanov & Noga Vardi. (2016) The TRPM1 channel in ON-bipolar cells is gated by both the α and the βγ subunits of the G-protein Go. Scientific Reports 6:1.
Crossref
Dhananjay P. ThakurJin-bin TianJaepyo JeonJian XiongYu HuangVeit Flockerzi & Michael X. Zhu. (2016) Critical roles of G i/o proteins and phospholipase C-δ1 in the activation of receptor-operated TRPC4 channels . Proceedings of the National Academy of Sciences 113:4, pages 1092-1097.
Crossref
Katherine Stuhrman & Aaron G. Roseberry. (2015) Neurotensin inhibits both dopamine- and GABA-mediated inhibition of ventral tegmental area dopamine neurons. Journal of Neurophysiology 114:3, pages 1734-1745.
Crossref
JongYun Myeong, Misun Kwak, Jae-Pyo Jeon, Chansik Hong, Ju-hong Jeon & Insuk So. (2015) Close spatio-association of the transient receptor potential canonical 4 (TRPC4) channel with Gα i in TRPC4 activation process . American Journal of Physiology-Cell Physiology 308:11, pages C879-C889.
Crossref
Neelima Khairatkar-Joshi, Daisy M Shah, Indranil Mukhopadhyay, VS Prasadarao Lingam & Abraham Thomas. (2015) TRPC channel modulators and their potential therapeutic applications. Pharmaceutical Patent Analyst 4:3, pages 207-218.
Crossref
Sonya M. Marshall-GradisnikPeter SmithEkua W. BrenuBernd NiliusSandra B. RamosDonald R. Staines. (2017) Examination of Single Nucleotide Polymorphisms (SNPs) in Transient Receptor Potential (TRP) Ion Channels in Chronic Fatigue Syndrome Patients. Immunology and Immunogenetics Insights 7, pages III.S25147.
Crossref
Giorgio Santoni, Claudio Cardinali, Maria Morelli, Matteo Santoni, Massimo Nabissi & Consuelo Amantini. (2015) Danger- and pathogen-associated molecular patterns recognition by pattern-recognition receptors and ion channels of the transient receptor potential family triggers the inflammasome activation in immune cells and sensory neurons. Journal of Neuroinflammation 12:1, pages 21.
Crossref
Jongyun Myeong, Misun Kwak, Chansik Hong, Ju-Hong Jeon & Insuk So. (2014) Identification of a Membrane-targeting Domain of the Transient Receptor Potential Canonical (TRPC)4 Channel Unrelated to Its Formation of a Tetrameric Structure. Journal of Biological Chemistry 289:50, pages 34990-35002.
Crossref
Marc Freichel, Volodymyr Tsvilovskyy & Juan E. Camacho-Londoño. 2014. Mammalian Transient Receptor Potential (TRP) Cation Channels. Mammalian Transient Receptor Potential (TRP) Cation Channels 85 128 .

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.