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Brief Report

DNA Methylation Profile at the DNMT3L Promoter: A Potential Biomarker for Cervical Cancer

Pages 80-85 | Published online: 03 May 2007

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Kourosh Shahraki, Kianoush Shahraki, Paria Ghasemi Boroumand & Roghayeh Sheervalilou. (2023) Promotor methylation in ocular surface squamous neoplasia development: epigenetics implications in molecular diagnosis. Expert Review of Molecular Diagnostics 23:9, pages 753-769.
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Jae-Sung Kim, Sun Young Kim, Minyoung Lee, Sung Hyun Kim, Sang-Man Kim & Eun Ju Kim. (2015) Radioresistance in a human laryngeal squamous cell carcinoma cell line is associated with DNA methylation changes and topoisomerase II α. Cancer Biology & Therapy 16:4, pages 558-566.
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Michael S. Samuel, Michael S. Samuel, Therèse Lundgren-May & Matthias Ernst. (2007) Identification of putative targets of DNA (cytosine-5) methylation-mediated transcriptional silencing using a novel conditionally active form of DNA methyltransferase 3a. Growth Factors 25:6, pages 426-436.
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Articles from other publishers (33)

Saurav Panicker & Satish Ramalingam. 2023. Cancer Genes: Volume 2. Cancer Genes: Volume 2 274 312 .
Kosaku Okuda, Kengo Nakahara, Akihiro Ito, Yuta Iijima, Ryosuke Nomura, Ashutosh Kumar, Kana Fujikawa, Kazuya Adachi, Yuki Shimada, Satoshi Fujio, Reina Yamamoto, Nobumasa Takasugi, Kunishige Onuma, Mitsuhiko Osaki, Futoshi Okada, Taichi Ukegawa, Yasuo Takeuchi, Norihisa Yasui, Atsuko Yamashita, Hiroyuki Marusawa, Yosuke Matsushita, Toyomasa Katagiri, Takahiro Shibata, Koji Uchida, Sheng-Yong Niu, Nhi B. Lang, Tomohiro Nakamura, Kam Y. J. Zhang, Stuart A. Lipton & Takashi Uehara. (2023) Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis. Nature Communications 14:1.
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Sannidhi Bhootra, Nandana Jill, Geetha Shanmugam, Sudeshna Rakshit & Koustav Sarkar. (2023) DNA methylation and cancer: transcriptional regulation, prognostic, and therapeutic perspective. Medical Oncology 40:2.
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Ecaterina Isacescu, Cornelia Braicu, Laura Pop, Ioana Berindan-Neagoe & Cristina Stefan. 2022. Epigenetics and Anticipation. Epigenetics and Anticipation 167 196 .
Ponne Saravanaraman, Murugan Selvam, Cheemala Ashok, Loudu Srijyothi & Sudhakar Baluchamy. (2020) De novo methyltransferases: Potential players in diseases and new directions for targeted therapy. Biochimie 176, pages 85-102.
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Vasiliki Tzelepi, Souzana Logotheti, Eleni Efstathiou, Patricia Troncoso, Ana Aparicio, Minas Sakellakis, Anh Hoang, Petros Perimenis, Maria Melachrinou, Christopher Logothetis & Vasiliki Zolota. (2020) Epigenetics and prostate cancer: defining the timing of DNA methyltransferase deregulation during prostate cancer progression. Pathology 52:2, pages 218-227.
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Ritwija Bhattacharya, Shrinjana Dhar, Aniruddha Mukhopadhyay & Pritha Bhattacharjee. 2020. Pharmacotherapeutic Botanicals for Cancer Chemoprevention. Pharmacotherapeutic Botanicals for Cancer Chemoprevention 121 142 .
Fei Zheng & Huimin Yu. (2017) RASSF1A promoter methylation was associated with the development, progression and metastasis of cervical carcinoma: a meta-analysis with trial sequential analysis. Archives of Gynecology and Obstetrics 297:2, pages 467-477.
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Grégoire Rondelet & Johan Wouters. (2017) Human DNA (cytosine-5)-methyltransferases: a functional and structural perspective for epigenetic cancer therapy. Biochimie 139, pages 137-147.
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Joyce J. Thompson & Keith D. Robertson. 2017. DNA and Histone Methylation as Cancer Targets. DNA and Histone Methylation as Cancer Targets 97 124 .
Sun Young Kim, Dong-Yeop Shin, Sang-Man Kim, Minyoung Lee & Eun Ju Kim. (2016) Aberrant DNA methylation-induced gene inactivation is associated with the diagnosis and/or therapy of T-cell leukemias. Leukemia Research 47, pages 116-122.
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Patrizia D’Aquila, Dina Bellizzi & Giuseppe Passarino. (2015) Mitochondria in health, aging and diseases: the epigenetic perspective. Biogerontology 16:5, pages 569-585.
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Ming Li, Mario A. Cleves, Himel Mallick, Stephen W. Erickson, Xinyu Tang, Todd G. Nick, Stewart L. Macleod & Charlotte A. Hobbs. (2014) A genetic association study detects haplotypes associated with obstructive heart defects. Human Genetics 133:9, pages 1127-1138.
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Dharmalingam Subramaniam, Ravi Thombre, Animesh Dhar & Shrikant Anant. (2014) DNA Methyltransferases: A Novel Target for Prevention and Therapy. Frontiers in Oncology 4.
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Amitava Basu, Vasanthi Dasari, Rakesh K. Mishra & Sanjeev Khosla. (2014) The CpG Island Encompassing the Promoter and First Exon of Human DNMT3L Gene Is a PcG/TrX Response Element (PRE). PLoS ONE 9:4, pages e93561.
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Gopinathan Gokul & Sanjeev Khosla. 2013. Epigenetics: Development and Disease. Epigenetics: Development and Disease 597 625 .
Hung‐Fu Liao, Kang‐Yu Tai, Wendy S.‐C. Chen, Luca C.W. Cheng, Hong‐Nerng Ho & Shau‐Ping Lin. (2012) Functions of DNA methyltransferase 3‐like in germ cells and beyond. Biology of the Cell 104:10, pages 571-587.
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Natalia V. Cucu. 2011. Nutrition in Epigenetics. Nutrition in Epigenetics 9 45 .
Shuping Zhao, Guixia Sun, Parks W. Tony, Dehua Ma & Chengquan Zhao. (2010) Expression and methylation status of the Syk gene in cervical carcinoma. Archives of Gynecology and Obstetrics 283:5, pages 1113-1119.
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Musa Drini, Nicholas C. Wong, Hamish S. Scott, Jeffrey M. Craig, Alexander Dobrovic, Chelsee A. Hewitt, Christofer Dow, Joanne P. Young, Mark A. Jenkins, Richard Saffery & Finlay A. Macrae. (2011) Investigating the Potential Role of Genetic and Epigenetic Variation of DNA Methyltransferase Genes in Hyperplastic Polyposis Syndrome. PLoS ONE 6:2, pages e16831.
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Hai-Yan Cheng, Xiu-Wei Chen, Li Cheng, Yun-Duo Liu & Ge Lou. (2010) DNA methylation and carcinogenesis of PRDM5 in cervical cancer. Journal of Cancer Research and Clinical Oncology 136:12, pages 1821-1825.
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Guru Prasad Manderwad, Gopinathan Gokul, Chitra Kannabiran, Santosh G. Honavar, Sanjeev Khosla & Geeta K. Vemuganti. (2010) Hypomethylation of the DNMT3L Promoter in Ocular Surface Squamous Neoplasia . Archives of Pathology & Laboratory Medicine 134:8, pages 1193-1196.
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Sophie RousseauxSaadi Khochbin. (2009) New hypotheses for large-scale epigenome alterations in somatic cancer cells: a role for male germ-cell-specific regulators. Epigenomics 1:1, pages 153-161.
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Michael S. Samuel, Hiromu Suzuki, Michael Buchert, Tracy L. Putoczki, Niall C. Tebbutt, Therése Lundgren–May, Aliki Christou, Melissa Inglese, Minoru Toyota, Joan K. Heath, Robyn L. Ward, Paul M. Waring & Matthias Ernst. (2009) Elevated Dnmt3a Activity Promotes Polyposis in ApcMin Mice by Relaxing Extracellular Restraints on Wnt Signaling. Gastroenterology 137:3, pages 902-913.e11.
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Hirendra Nath BanerjeeMukesh Verma. (2009) Epigenetic mechanisms in cancer. Biomarkers in Medicine 3:4, pages 397-410.
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Igor P. Pogribny & Frederick A. Beland. (2009) DNA hypomethylation in the origin and pathogenesis of human diseases. Cellular and Molecular Life Sciences 66:14, pages 2249-2261.
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Kyle R. Pomraning, Kristina M. Smith & Michael Freitag. (2009) Genome-wide high throughput analysis of DNA methylation in eukaryotes. Methods 47:3, pages 142-150.
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Olaf Hopfer, Martina Komor, Ina Sabine Koehler, Claudia Freitag, Matthias Schulze, Dieter Hoelzer, Eckhard Thiel & Wolf-Karsten Hofmann. (2009) Aberrant promotor methylation in MDS hematopoietic cells during in vitro lineage specific differentiation is differently associated with DNMT isoforms. Leukemia Research 33:3, pages 434-442.
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Divya Tej Sowpati, Devi Thiagarajan, Sudhish Sharma, Hina Sultana, Rosalind John, Azim Surani, Rakesh Kumar Mishra & Sanjeev Khosla. (2008) An intronic DNA sequence within the mouse Neuronatin gene exhibits biochemical characteristics of an ICR and acts as a transcriptional activator in Drosophila. Mechanisms of Development 125:11-12, pages 963-973.
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Nicholas C. Wong, Ruth Morley, Richard Saffery & Jeffrey M. Craig. (2008) Archived Guthrie blood spots as a novel source for quantitative DNA methylation analysis. BioTechniques 45:4, pages 423-430.
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Ye-Guang Hu, Ryutaro Hirasawa, Jia-Lei Hu, Kenichiro Hata, Chun-Liang Li, Ying Jin, Taiping Chen, En Li, Muriel Rigolet, Evani Viegas-Péquignot, Hiroyuki Sasaki & Guo-Liang Xu. (2008) Regulation of DNA methylation activity through Dnmt3L promoter methylation by Dnmt3 enzymes in embryonic development. Human Molecular Genetics 17:17, pages 2654-2664.
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Sophie Rousseaux, Nicolas Reynoird, Jonathan Gaucher & Saadi Khochbin. (2008) L’intrusion des régulateurs de l’épigénome mâle dans les cellules somatiques cancéreuses. médecine/sciences 24:8-9, pages 735-741.
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Ying Yu, Huanmin Zhang, Fei Tian, Wensheng Zhang, Hongbin Fang & Jiuzhou Song. (2008) An Integrated Epigenetic and Genetic Analysis of DNA Methyltransferase Genes (DNMTs) in Tumor Resistant and Susceptible Chicken Lines. PLoS ONE 3:7, pages e2672.
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