1,274
Views
54
CrossRef citations to date
0
Altmetric
Research Paper

Methylation-mediated transcriptional repression of microRNAs during cervical carcinogenesis

, , , , , , & show all
Pages 220-228 | Received 24 Oct 2012, Accepted 14 Jan 2013, Published online: 16 Jan 2013

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (3)

Iris Babion, Lise M.A. De Strooper, Roosmarijn Luttmer, Maaike C.G. Bleeker, Chris J.L.M. Meijer, Daniëlle A.M. Heideman, Saskia M. Wilting & Renske D.M. Steenbergen. (2019) Complementarity between miRNA expression analysis and DNA methylation analysis in hrHPV-positive cervical scrapes for the detection of cervical disease. Epigenetics 14:6, pages 558-567.
Read now
Renée MF Ebisch, Albert G Siebers, Remko P Bosgraaf, Leon FAG Massuger, Ruud LM Bekkers & Willem JG Melchers. (2016) Triage of high-risk HPV positive women in cervical cancer screening. Expert Review of Anticancer Therapy 16:10, pages 1073-1085.
Read now
Eva M. Riedmann. (2013) Landes Highlights. RNA Biology 10:3, pages 335-336.
Read now

Articles from other publishers (51)

Hui Wang, Wen-Hao Wang, Wei Wang, Ji-Hong Ma, Xiao-Qiang Su, Li-Li Zhang, Yong-Li Hou, Jian-Bing Liu, Jing-Jing Ren, Xiao-Lin Luo & Min Hao. (2024) Folate deficiency promotes cervical squamous carcinoma SiHa cells progression by targeting miR-375/FZD4/β-catenin signaling. The Journal of Nutritional Biochemistry 124, pages 109489.
Crossref
Elham Hasheminasabgorji, Mohammad Amir Mishan, Mohammad Amin Khazeei Tabari & Abouzar Bagheri. (2023) miR-638: A Promising Cancer Biomarker with Therapeutic Potential. Current Molecular Medicine 23:5, pages 377-389.
Crossref
Mengfei Xu, Angelina Huseinovic, Annelieke Jaspers, Lushun Yuan & Renske D. M. Steenbergen. (2023) Downregulation of miR‐193a/b‐3p during HPV‐induced cervical carcinogenesis contributes to anchorage‐independent growth through PI3K–AKT pathway regulators. Journal of Medical Virology 95:3.
Crossref
Pui-Wah Choi, Tin Lun Liu, Chun Wai Wong, Sze Kei Liu, Yick-Liang Lum & Wai-Kit Ming. (2022) The Dysregulation of MicroRNAs in the Development of Cervical Pre-Cancer—An Update. International Journal of Molecular Sciences 23:13, pages 7126.
Crossref
Angelina Huseinovic, Annelieke Jaspers, Annina P. van Splunter, Hanne Sørgård, Saskia M. Wilting, Dorian R. A. Swarts, Ida H. van der Meulen, Victor W. van Beusechem, Renée X. de Menezes & Renske D. M. Steenbergen. (2022) Functional Screen for microRNAs Suppressing Anchorage-Independent Growth in Human Cervical Cancer Cells. International Journal of Molecular Sciences 23:9, pages 4791.
Crossref
Marina S. Gubenko, Vitaliy I. Loginov, Aleksey M. Burdennyy, Irina V. Pronina, Svetlana V. Khokhlova & Sergey S. Pertsov. (2022) Role of Microribonucleic acid in the Carcinogenesis of Non-Small-Cell Lung Cancer. I.P. Pavlov Russian Medical Biological Herald 30:1, pages 123-132.
Crossref
Miao Tian, Yu-Bo Han, Cheng-Cheng Zhao, Li Liu & Fu-Li Zhang. (2021) Hesperidin alleviates insulin resistance by improving HG-induced oxidative stress and mitochondrial dysfunction by restoring miR-149. Diabetology & Metabolic Syndrome 13:1.
Crossref
Brigitta László, László Antal, Eszter Gyöngyösi, Anita Szalmás, Szilárd Póliska, György Veress & József Kónya. (2021) Coordinated action of human papillomavirus type 16 E6 and E7 oncoproteins on competitive endogenous RNA (ceRNA) network members in primary human keratinocytes. BMC Cancer 21:1.
Crossref
Neda Rahimian, Zahra Sadat Razavi, Fatemeh Aslanbeigi, Amir Masoud Mirkhabbaz, Haleh Piroozmand, Mohammad Karim Shahrzad, Michael R. Hamblin & Hamed Mirzaei. (2021) Non-coding RNAs related to angiogenesis in gynecological cancer. Gynecologic Oncology 161:3, pages 896-912.
Crossref
Javid Sadri Nahand, Layla Shojaie, Seyed Amirreza Akhlagh, Mohammad Saeid Ebrahimi, Hamid Reza Mirzaei, Hossein Bannazadeh Baghi, Maryam Mahjoubin-Tehran, Nima Rezaei, Michael R. Hamblin, Vida Tajiknia, Neda Rahimian & Hamed Mirzaei. (2021) Cell death pathways and viruses: Role of microRNAs. Molecular Therapy - Nucleic Acids 24, pages 487-511.
Crossref
Yang Liu, Qiuyuan Wang, Jie Wen, Yiru Wu & Chaolai Man. (2021) MiR-375: A novel multifunctional regulator. Life Sciences 275, pages 119323.
Crossref
Shuna Shen, Shengbin Zhang, Ping Liu, Junfei Wang & Haiyan Du. (2020) Potential role of microRNAs in the treatment and diagnosis of cervical cancer. Cancer Genetics 248-249, pages 25-30.
Crossref
Li-Jian Chen, Miao-Xian Yuan, Chun-Yi Ji, Yan-Bing Zhang, Yu-Ming Peng, Tian Zhang, Hong-Qiang Gao, Xin-Yi Sheng, Zhao-Yang Liu, Wei-Xin Xie & Qiang Yin. (2020) Long Non-Coding RNA CRNDE Regulates Angiogenesis in Hepatoblastoma by Targeting the MiR-203/VEGFA Axis. Pathobiology 87:3, pages 161-170.
Crossref
Shizhi Wang, Haixia Zhu, Bo Ding, Xinrui Feng, Wenxuan Zhao, Mengjing Cui, Yuling Xu, Minxin Shi, Jian Chen & Hua Jin. (2019) Genetic variants in microRNAs are associated with cervical cancer risk. Mutagenesis 34:2, pages 127-133.
Crossref
Ondrej Ondič, Jana Němcová, Reza Alaghehbandan, Kateřina Černá, Barbora Gomolčáková, Iva Kinkorová–Luňáčková, Jan Chytra, Henrieta Šidlová, Ondřej Májek & Jiří Bouda. (2019) The detection of DNA methylation of tumor suppressor genes in cervical HSIL : a prospective cytologic–histologic correlation study of 70 cases . Cytopathology.
Crossref
Jennifer Hern�ndez-Ju�rez, Orlando Vargas-Sierra, Luis Herrera, David Cant� De Le�n, Jorge Fern�ndez-Retana, Carlos P�rez-Plasencia, C�sar L�pez-Camarillo, Patricio Gariglio & Jos� D�az-Ch�vez. (2019) Sodium-coupled monocarboxylate transporter is a target of epigenetic repression in cervical cancer. International Journal of Oncology.
Crossref
Barbara C. Snoek, Wina Verlaat, Iris Babion, Putri W. Novianti, Mark A. van de Wiel, Saskia M. Wilting, Nienke E. van Trommel, Maaike C.G. Bleeker, Leon F.A.G. Massuger, Willem J.G. Melchers, Daoud Sie, Daniëlle A.M. Heideman, Peter J.F. Snijders, Chris J.L.M. Meijer & Renske D.M. Steenbergen. (2019) Genome-wide microRNA analysis of HPV-positive self-samples yields novel triage markers for early detection of cervical cancer. International Journal of Cancer 144:2, pages 372-379.
Crossref
Iris Babion, Barbara C. Snoek, Putri W. Novianti, Annelieke Jaspers, Nienke van Trommel, Daniëlle A. M. Heideman, Chris J. L. M. Meijer, Peter J. F. Snijders, Renske D. M. Steenbergen & Saskia M. Wilting. (2018) Triage of high-risk HPV-positive women in population-based screening by miRNA expression analysis in cervical scrapes; a feasibility study. Clinical Epigenetics 10:1.
Crossref
Xiaoni Liu, Shuang Wang, Jianji Xu, Buxin Kou, Dexi Chen, Yajie Wang & Xiaoxin Zhu. (2018) Extract of Stellerachamaejasme L(ESC) inhibits growth and metastasis of human hepatocellular carcinoma via regulating microRNA expression. BMC Complementary and Alternative Medicine 18:1.
Crossref
MK Sannigrahi, R Sharma, NK Panda & M Khullar. (2018) Role of non-coding RNAs in head and neck squamous cell carcinoma: A narrative review. Oral Diseases 24:8, pages 1417-1427.
Crossref
M. K. Sannigrahi, Rajni Sharma, Varinder Singh, Naresh K. Panda, Vidya Rattan & Madhu Khullar. (2018) DNA methylation regulated microRNAs in HPV-16-induced head and neck squamous cell carcinoma (HNSCC). Molecular and Cellular Biochemistry 448:1-2, pages 321-333.
Crossref
Yingru Zhi, Hao Zhou, Abudoureyimu Mubalake, Ying Chen, Bei Zhang, Kai Zhang, Xiaoyuan Chu & Rui Wang. (2018) Regulation and functions of Micro RNA ‐149 in human cancers . Cell Proliferation 51:5.
Crossref
Byungho Lim, Hee‐Jin Kim, Haejeong Heo, Nanhyung Huh, Su‐Jin Baek, Jong‐Hwan Kim, Dong‐Hyuck Bae, Eun‐Hye Seo, Sang‐Il Lee, Kyu‐Sang Song, Seon‐Young Kim, Yong Sung Kim & Mirang Kim. (2018) Epigenetic silencing of miR‐1271 enhances MEK1 and TEAD4 expression in gastric cancer. Cancer Medicine 7:7, pages 3411-3424.
Crossref
Rui-Da Xu, Fan Feng, Xiao-Sheng Yu, Zu-De Liu & Li-Feng Lao. (2018) miR-149-5p inhibits cell growth by regulating TWEAK/Fn14/PI3K/AKT pathway and predicts favorable survival in human osteosarcoma. International Journal of Immunopathology and Pharmacology 32, pages 205873841878665.
Crossref
Prakriti Sen, Pooja Ganguly & Niladri Ganguly. (2017) Modulation of DNA methylation by human papillomavirus E6 and E7 oncoproteins in cervical cancer (Review). Oncology Letters.
Crossref
Maximilian Stich, Lennard Ganss, Jens Puschhof, Elena-Sophie Prigge, Miriam Reuschenbach, Ana Guiterrez, Svetlana Vinokurova & Magnus von Knebel Doeberitz. (2016) 5-aza-2′-deoxycytidine (DAC) treatment downregulates the HPV E6 and E7 oncogene expression and blocks neoplastic growth of HPV-associated cancer cells. Oncotarget 8:32, pages 52104-52117.
Crossref
Adrien Morel, Aurélie Baguet, Jérôme Perrard, Caroline Demeret, Elise Jacquin, David Guenat, Christiane Mougin & Jean-Luc Prétet. (2017) 5azadC treatment upregulates miR-375 level and represses HPV16 E6 expression. Oncotarget 8:28, pages 46163-46176.
Crossref
Julia Durzynska, Krzysztof Lesniewicz & Elzbieta Poreba. (2017) Human papillomaviruses in epigenetic regulations. Mutation Research/Reviews in Mutation Research 772, pages 36-50.
Crossref
Yimin Ge & Ming Guo. 2017. Precision Molecular Pathology of Uterine Cancer. Precision Molecular Pathology of Uterine Cancer 253 278 .
Saskia M. Wilting & Renske D.M. Steenbergen. (2016) Molecular events leading to HPV-induced high grade neoplasia. Papillomavirus Research 2, pages 85-88.
Crossref
Aline de Conti, Volodymyr Tryndyak, Daniel R. Doerge, Frederick A. Beland & Igor P. Pogribny. (2016) Irreversible down-regulation of miR-375 in the livers of Fischer 344 rats after chronic furan exposure. Food and Chemical Toxicology 98, pages 2-10.
Crossref
Mehri Seifoleslami, Maryam Khayyat Khameneie, Fatemeh Mashayekhi, Farnoush Sedaghati, Katayoun Ziari, Kowsar Mansouri & Aghdas Safari. (2015) RETRACTED ARTICLE: Identification of microRNAs (miR-203/miR-7) as potential markers for the early detection of lymph node metastases in patients with cervical cancer. Tumor Biology 37:12, pages 16393-16393.
Crossref
Shikai Liu, Lili Song, Hairong Yao, Liang Zhang, Dongkui Xu, Fangyuan Gao & Qian Li. (2016) MiR-375 Is Epigenetically Downregulated by HPV-16 E6 Mediated DNMT1 Upregulation and Modulates EMT of Cervical Cancer Cells by Suppressing lncRNA MALAT1. PLOS ONE 11:9, pages e0163460.
Crossref
Saskia M. Wilting, Viktorian Miok, Annelieke Jaspers, Debby Boon, Hanne Sørgård, Malin Lando, Barbara C. Snoek, Wessel N. van Wieringen, Chris J.L.M. Meijer, Heidi Lyng, Peter J.F. Snijders & Renske D.M. Steenbergen. (2016) Aberrant methylation-mediated silencing of microRNAs contributes to HPV-induced anchorage independence. Oncotarget 7:28, pages 43805-43819.
Crossref
MIN HAO, WEIHONG ZHAO, LILI ZHANG, HONGHONG WANG & XIN YANG. (2016) Low folate levels are associated with methylation-mediated transcriptional repression of miR-203 and miR-375 during cervical carcinogenesis. Oncology Letters 11:6, pages 3863-3869.
Crossref
HILDA JIMÉNEZ-WENCES, DINORAH NASHELY MARTÍNEZ-CARRILLO, OSCAR PERALTA-ZARAGOZA, GABRIELA ELIZABETH CAMPOS-VIGURI, DANIEL HERNÁNDEZ-SOTELO, MARCO ANTONIO JIMÉNEZ-LÓPEZ, JOSÉ GUADALUPE MUÑOZ-CAMACHO, VÍCTOR HUGO GARZÓN-BARRIENTOS, BERENICE ILLADES-AGUIAR & GLORIA FERNÁNDEZ-TILAPA. (2016) Methylation and expression of miRNAs in precancerous lesions and cervical cancer with HPV16 infection. Oncology Reports 35:4, pages 2297-2305.
Crossref
Giuseppina D’Andrilli. 2016. Gynecological Cancers. Gynecological Cancers 51 64 .
Olga V Kurmyshkina, Pavel I Kovchur & Tatyana O Volkova. (2015) 'Drawing' a Molecular Portrait of CIN and Cervical Cancer: a Review of Genome-Wide Molecular Profiling Data. Asian Pacific Journal of Cancer Prevention 16:11, pages 4477-4487.
Crossref
V. I. Loginov, S. V. Rykov, M. V. Fridman & E. A. Braga. (2015) Methylation of miRNA genes and oncogenesis. Biochemistry (Moscow) 80:2, pages 145-162.
Crossref
Qiong Wu, Zhiping Yang, Lin Xia, Yongzhan Nie, Kaichun Wu, Yongquan Shi & Daiming Fan. (2014) Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters. Oncotarget 5:22, pages 11552-11563.
Crossref
Jun-Wei Yan, Ju-Sheng Lin & Xing-Xing He. (2014) The emerging role of miR-375 in cancer. International Journal of Cancer 135:5, pages 1011-1018.
Crossref
Sascha Venturelli, Tobias W. Sinnberg, Alexander Berger, Seema Noor, Mitchell Paul Levesque, Alexander Böcker, Heike Niessner, Ulrich M. Lauer, Michael Bitzer, Claus Garbe & Christian Busch. (2014) Epigenetic Impacts of Ascorbate on Human Metastatic Melanoma Cells. Frontiers in Oncology 4.
Crossref
HILDA JIMÉNEZ-WENCES, OSCAR PERALTA-ZARAGOZA & GLORIA FERNÁNDEZ-TILAPA. (2014) Human papilloma virus, DNA methylation and microRNA expression in cervical cancer (Review). Oncology Reports 31:6, pages 2467-2476.
Crossref
Renske D. M. Steenbergen, Peter J. F. Snijders, Daniëlle A. M. Heideman & Chris J. L. M. Meijer. (2014) Clinical implications of (epi)genetic changes in HPV-induced cervical precancerous lesions. Nature Reviews Cancer 14:6, pages 395-405.
Crossref
Jinchuan Fang, Hai Zhang & Sufang Jin. (2014) Epigenetics and cervical cancer: from pathogenesis to therapy. Tumor Biology 35:6, pages 5083-5093.
Crossref
Yi-Wen Huang, Chieh-Ti Kuo, Jo-Hsin Chen, Paul J. Goodfellow, Tim H.-M. Huang, Janet S. Rader & Denise S. Uyar. (2014) Hypermethylation of miR-203 in endometrial carcinomas. Gynecologic Oncology 133:2, pages 340-345.
Crossref
Yingjie Shao, Yiting Geng, Wendong Gu, Jin Huang, Zhonghua Ning & Honglei Pei. (2014) Prognostic Significance of MicroRNA-375 Downregulation in Solid Tumors: A Meta-Analysis. Disease Markers 2014, pages 1-10.
Crossref
Kouji Banno, Miho Iida, Megumi Yanokura, Iori Kisu, Takashi Iwata, Eiichiro Tominaga, Kyoko Tanaka & Daisuke Aoki. (2014) MicroRNA in Cervical Cancer: OncomiRs and Tumor Suppressor miRs in Diagnosis and Treatment. The Scientific World Journal 2014, pages 1-8.
Crossref
Jiazeng Xia, Xiaoqiang Guo & Kaiyuan Deng. 2014. MicroRNAs: Key Regulators of Oncogenesis. MicroRNAs: Key Regulators of Oncogenesis 29 57 .
BRANISLAV RUTTKAY-NEDECKY, ANA MARIA JIMENEZ JIMENEZ, LUKAS NEJDL, DAGMAR CHUDOBOVA, JAROMIR GUMULEC, MICHAL MASARIK, VOJTECH ADAM & RENE KIZEK. (2013) Relevance of infection with human papillomavirus: The role of the p53 tumor suppressor protein and E6/E7 zinc finger proteins. International Journal of Oncology 43:6, pages 1754-1762.
Crossref
Ah-Ng Tony Kong, Chengyue Zhang & Zheng-Yuan Su. (2013) Targeting Epigenetics for Cancer Prevention By Dietary Cancer Preventive Compounds—The Case of miRNA. Cancer Prevention Research 6:7, pages 622-624.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.