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Epigenetics Volume 8, 2013 - Issue 11
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Research Paper

SUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase

Murilo TD Bueno Terry Fox Molecular Oncology Group and the Bloomfield Center for Research on Aging; Sir Mortimer B Davis Jewish General Hospital; Lady Davis Institute for Medical Research; Montréal, QC Canada; Department of Medicine and Oncology; McGill University; Montréal, QC Canada
&
Stéphane Richard Terry Fox Molecular Oncology Group and the Bloomfield Center for Research on Aging; Sir Mortimer B Davis Jewish General Hospital; Lady Davis Institute for Medical Research; Montréal, QC Canada; Department of Medicine and Oncology; McGill University; Montréal, QC CanadaCorrespondence[email protected]
Pages 1162-1175 | Received 01 Aug 2013, Accepted 12 Aug 2013, Published online: 22 Aug 2013

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Seung Eun Yu, Su Hyung Park & Yeun Kyu Jang. (2018) Sumoylation of the histone demethylase KDM4A is required for binding to tumor suppressor p53 in HCT116 colon cancer cell lines. Animal Cells and Systems 22:1, pages 22-28.
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Articles from other publishers (27)

Kailang Li, Yongming Xia, Jian He, Jie Wang, Jingyun Li, Meng Ye & Xiaofeng Jin. (2023) The SUMOylation and ubiquitination crosstalk in cancer. Journal of Cancer Research and Clinical Oncology 149:17, pages 16123-16146.
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Elena Di Nisio, Valerio Licursi, Cecilia Mannironi, Valentina Buglioni, Alessandro Paiardini, Giulia Robusti, Roberta Noberini, Tiziana Bonaldi & Rodolfo Negri. (2023) A truncated and catalytically inactive isoform of KDM5B histone demethylase accumulates in breast cancer cells and regulates H3K4 tri-methylation and gene expression. Cancer Gene Therapy 30:6, pages 822-832.
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Feng Guo, Yi Song, Lina Wu, Yanyan Zhao, Xiaojun Ma, Jiao Wang, Mingwei Shao, Hongfei Ji, Fengjuan Huang, Xunjie Fan, Shasha Wang, Guijun Qin & Baofeng Yang. (2023) SUMO specific peptidase 6 regulates the crosstalk between podocytes and glomerular endothelial cells in diabetic kidney disease. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1869:5, pages 166685.
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Bingluo Zhou, Yiran Zhu, Wenxia Xu, Qiyin Zhou, Linghui Tan, Liyuan Zhu, Hui Chen, Lifeng Feng, Tianlun Hou, Xian Wang, Dingwei Chen & Hongchuan Jin. (2021) Hypoxia Stimulates SUMOylation-Dependent Stabilization of KDM5B. Frontiers in Cell and Developmental Biology 9.
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Dean C. Singleton, Andrew Macann & William R. Wilson. (2021) Therapeutic targeting of the hypoxic tumour microenvironment. Nature Reviews Clinical Oncology 18:12, pages 751-772.
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Wesley N. Saintilnord & Yvonne Fondufe-Mittendorf. (2021) Arsenic-induced epigenetic changes in cancer development. Seminars in Cancer Biology 76, pages 195-205.
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Ya-Chu Chang, Marissa K. Oram & Anja-Katrin Bielinsky. (2021) SUMO-Targeted Ubiquitin Ligases and Their Functions in Maintaining Genome Stability. International Journal of Molecular Sciences 22:10, pages 5391.
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Julie-Aurore Losman, Peppi Koivunen & William G. KaelinJr.Jr.. (2020) 2-Oxoglutarate-dependent dioxygenases in cancer. Nature Reviews Cancer 20:12, pages 710-726.
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Xiaoli Fu, Chao Yang & Bin Yu. (2020) Targeting KDM5 Demethylases: Inhibition and Degradation. Current Topics in Medicinal Chemistry 20:4, pages 261-263.
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Chandrika Gowda, Chunhua Song, Yali Ding, Soumya Iyer, Pavan K Dhanyamraju, Mary McGrath, Yevgeniya Bamme, Mario Soliman, Shriya Kane, Jonathon L. Payne & Sinisa Dovat. (2020) Cellular signaling and epigenetic regulation of gene expression in leukemia. Advances in Biological Regulation 75, pages 100665.
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I-Ju Yeh, Emily Esakov, Justin D. Lathia, Masaru Miyagi, Ofer Reizes & Monica M. Montano. (2019) Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer. Scientific Reports 9:1.
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Nicolas Lebrun, Claire Mehler-Jacob, Karine Poirier, Cecile Zordan, Didier Lacombe, Nathalie Carion, Pierre Billuart & Thierry Bienvenu. (2018) Novel KDM5B splice variants identified in patients with developmental disorders: Functional consequences. Gene 679, pages 305-313.
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Lizhen Wu, Jian Cao, Wesley L. Cai, Sabine M. Lang, John R. Horton, Daniel J. Jansen, Zongzhi Z. Liu, Jocelyn F. Chen, Meiling Zhang, Bryan T. Mott, Katherine Pohida, Ganesha Rai, Stephen C. Kales, Mark J. Henderson, Xin Hu, Ajit Jadhav, David J. Maloney, Anton Simeonov, Shu Zhu, Akiko Iwasaki, Matthew D. Hall, Xiaodong Cheng, Gerald S. Shadel & Qin Yan. (2018) KDM5 histone demethylases repress immune response via suppression of STING. PLOS Biology 16:8, pages e2006134.
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Sabine A.G. Cuijpers, Edwin Willemstein & Alfred C.O. Vertegaal. (2017) Converging Small Ubiquitin-like Modifier (SUMO) and Ubiquitin Signaling: Improved Methodology Identifies Co-modified Target Proteins. Molecular & Cellular Proteomics 16:12, pages 2281-2295.
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Kayla M. Harmeyer, Nicole D. Facompre, Meenhard Herlyn & Devraj Basu. (2017) JARID1 Histone Demethylases: Emerging Targets in Cancer. Trends in Cancer 3:10, pages 713-725.
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Katarzyna Szarc vel Szic, Ken Declerck, René A.J. Crans, Jolien Diddens, David B. Scherf, Clarissa Gerhäuser & Wim Vanden Berghe. (2017) Epigenetic silencing of triple negative breast cancer hallmarks by Withaferin A. Oncotarget 8:25, pages 40434-40453.
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Wan-Shan Yang, Mel Campbell & Pei-Ching Chang. (2017) SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication. PLOS Pathogens 13:2, pages e1006216.
Crossref
Mengjiao Han, Wenxia Xu, Pu Cheng, Hongchuan Jin & Xian Wang. (2016) Histone demethylase lysine demethylase 5B in development and cancer. Oncotarget 8:5, pages 8980-8991.
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David Wotton, Lucy F. Pemberton & Jacqueline Merrill-Schools. 2017. SUMO Regulation of Cellular Processes. SUMO Regulation of Cellular Processes 35 50 .
Van G. Wilson. 2017. SUMO Regulation of Cellular Processes. SUMO Regulation of Cellular Processes 1 12 .
Ivo A. Hendriks & Alfred C. O. Vertegaal. (2016) A comprehensive compilation of SUMO proteomics. Nature Reviews Molecular Cell Biology 17:9, pages 581-595.
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Salminen Antero, Kaarniranta Kai & Kauppinen Anu. (2016) Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases. Aging and disease 7:2, pages 180.
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Nicole R. Wilson & Mark Hochstrasser. 2016. SUMO. SUMO 23 38 .
Ivo A. Hendriks, Louise W. Treffers, Matty Verlaan-de Vries, Jesper V. Olsen & Alfred C.O. Vertegaal. (2015) SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage. Cell Reports 10:10, pages 1778-1791.
Crossref
Zhenbang Chen & Wenfu Lu. (2015) Roles of Ubiquitination and SUMOylation on Prostate Cancer: Mechanisms and Clinical Implications. International Journal of Molecular Sciences 16:3, pages 4560-4580.
Crossref
Wenfu Lu, Shenji Liu, Bo Li, Yingqiu Xie, Christine Adhiambo, Qing Yang, Billy R. Ballard, Keiichi I. Nakayama, Robert J. Matusik & Zhenbang Chen. (2014) SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination. Oncotarget 6:2, pages 771-788.
Crossref
Merlin Butler, Syed Rafi, Waheeda Hossain, Dietrich Stephan & Ann Manzardo. (2015) Whole Exome Sequencing in Females with Autism Implicates Novel and Candidate Genes. International Journal of Molecular Sciences 16:1, pages 1312-1335.
Crossref

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