Advanced search
Publication Cover
Epigenetics Volume 9, 2014 - Issue 6
Submit an article Journal homepage
1,353
Views
21
CrossRef citations to date
0
Altmetric
Research Paper

A novel approach to the discovery of survival biomarkers in glioblastoma using a joint analysis of DNA methylation and gene expression

Ashley A Smith Department of Pathology and Laboratory Medicine; Brown University; Providence, RI USA
,
Yen-Tsung Huang Department of Epidemiology; Brown University; Providence, RI USA
,
Melissa Eliot Department of Epidemiology; Brown University; Providence, RI USA
,
E Andres Houseman Department of Public Health; Oregon State University; Corvallis, OR USA
,
Carmen J Marsit Department of Pharmacology and Toxicology; Geisel School of Medicine at Dartmouth; Hanover, NH USA; Department of Community and Family Medicine and Section of Biostatistics and Epidemiology; Geisel School of Medicine at Dartmouth; Dartmouth, NH USA
,
John K Wiencke Department of Neurological Surgery; University of California at San Francisco; San Francisco, CA USA
&
Karl T Kelsey Department of Pathology and Laboratory Medicine; Brown University; Providence, RI USA; Department of Epidemiology; Brown University; Providence, RI USACorrespondence[email protected]
 show all
Pages 873-883 | Received 15 Nov 2013, Accepted 17 Mar 2014, Published online: 26 Mar 2014

Citations (21)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Eric Smith, Yoko Tomita, Helen M. Palethorpe, Stuart Howell, Maryam Nakhjavani, Amanda R. Townsend, Timothy J. Price, Joanne P. Young & Jennifer E. Hardingham. (2019) Reduced aquaporin-1 transcript expression in colorectal carcinoma is associated with promoter hypermethylation. Epigenetics 14:2, pages 158-170.
Read now

Articles from other publishers (20)

Xue He, Weilong Zhang, Wei Fu, Xiaoni Liu, Ping Yang, Jing Wang, Mingxia Zhu, Shaoxiang Li, Wei Zhang, Xiuru Zhang, Gehong Dong, Changjian Yan, Yali Zhao, Zhiping Zeng & Hongmei Jing. (2023) The prognostic value of RASGEF1A RNA expression and DNA methylation in cytogenetically normal acute myeloid leukemia. Cancer Biomarkers 36:2, pages 103-116.
Crossref
Sizhong Guan, Linge Jian, Ye He, Yanna Su & Liping Zhou. (2022) Bioinformatic identification of differentially expressed genes regulated by DNA‐methylation in glioblastoma. European Journal of Neuroscience 55:5, pages 1278-1290.
Crossref
Qingfei Chu, Xinyu Gu, Qiuxian Zheng, Zixuan Guo, Dandan Shan, Jing Wang & Haihong Zhu. (2021) Long noncoding RNA SNHG4: a novel target in human diseases. Cancer Cell International 21:1.
Crossref
Mohammad Reza Alivand, Sajad Najafi, Sajjad Esmaeili, Dara Rahmanpour, Hossein Zhaleh & Yazdan Rahmati. (2021) Integrative analysis of DNA methylation and gene expression profiles to identify biomarkers of glioblastoma. Cancer Genetics 258-259, pages 135-150.
Crossref
M. Kalya, T. Beißbarth & A. E. Kel. (2021) Master Regulators Associated with Poor Prognosis in Glioblastoma Multiforme. Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry 15:4, pages 263-273.
Crossref
Zhonghe Shao, Ting Wang, Meng Zhang, Zhou Jiang, Shuiping Huang & Ping Zeng. (2021) IUSMMT: Survival mediation analysis of gene expression with multiple DNA methylation exposures and its application to cancers of TCGA. PLOS Computational Biology 17:8, pages e1009250.
Crossref
M.P. Kalya, T. Beisbarth & A. Kel. (2021) Master regulators associated with poor prognosis in glioblastoma multiforme. Biomeditsinskaya Khimiya 67:3, pages 201-212.
Crossref
Ivana Jovčevska. (2020) Next Generation Sequencing and Machine Learning Technologies Are Painting the Epigenetic Portrait of Glioblastoma. Frontiers in Oncology 10.
Crossref
Lu Liu, Ping Zeng, Sheng Yang & Zhongshang Yuan. (2020) Leveraging methylation to identify the potential causal genes associated with survival in lung adenocarcinoma and lung squamous cell carcinoma. Oncology Letters.
Crossref
Shifeng Kan, Song Chai, Wenhua Chen & Bo Yu. (2019) DNA methylation profiling identifies potentially significant epigenetically‑regulated genes in glioblastoma multiforme. Oncology Letters.
Crossref
Adib Shafi, Tin Nguyen, Azam Peyvandipour, Hung Nguyen & Sorin Draghici. (2019) A Multi-Cohort and Multi-Omics Meta-Analysis Framework to Identify Network-Based Gene Signatures. Frontiers in Genetics 10.
Crossref
Lisa A. Maier, Arnold R. Brody & David A. Schwartz. (2018) Introduction to the 60th Annual Thomas L. Petty Aspen Lung Conference. Environment and Global Lung Health: Exposure, Susceptibility, and Intervention. Annals of the American Thoracic Society 15:Supplement_2, pages S61-S63.
Crossref
Yen‐Tsung HuangTianxi CaiEunhee Kim. (2016) Integrative genomic testing of cancer survival using semiparametric linear transformation models. Statistics in Medicine 35:16, pages 2831-2844.
Crossref
Yen-Tsung HuangTianxi Cai. (2016) Mediation analysis for survival data using semiparametric probit models. Biometrics 72:2, pages 563-574.
Crossref
Li Xu, Liang Fengji, Liu Changning, Zhang Liangcai, Li Yinghui, Li Yu, Chen Shanguang & Xiong Jianghui. (2015) Comparison of the Prognostic Utility of the Diverse Molecular Data among lncRNA, DNA Methylation, microRNA, and mRNA across Five Human Cancers. PLOS ONE 10:11, pages e0142433.
Crossref
Lawrence B. SchookTiago V. CollaresKwame A. Darfour-OduroArun Kumar DeLaurie A. RundKyle M. SchachtschneiderFabiana K. Seixas. (2015) Unraveling the Swine Genome: Implications for Human Health. Annual Review of Animal Biosciences 3:1, pages 219-244.
Crossref
Feng Zhang, Xiao Xiao, Jingcan Hao, Sen Wang, Yan Wen & Xiong Guo. (2015) CPAS: A trans-omics pathway analysis tool for jointly analyzing DNA copy number variations and mRNA expression profiles data. Journal of Biomedical Informatics 53, pages 363-366.
Crossref
Yen-Tsung Huang. (2015) Integrative modeling of multi-platform genomic data under the framework of mediation analysis. Statistics in Medicine 34:1, pages 162-178.
Crossref
Todd G. Rubin, Jason D. Gray & Bruce S. McEwen. (2014) Experience and the ever-changing brain: What the transcriptome can reveal. BioEssays 36:11, pages 1072-1081.
Crossref
Yen-Tsung Huang. (2014) Integrative modeling of multiple genomic data from different types of genetic association studies. Biostatistics 15:4, pages 587-602.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.