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SUMO engages multiple corepressors to regulate chromatin structure and transcription

Pages 440-444 | Received 01 Jun 2009, Accepted 14 Aug 2009, Published online: 01 Oct 2009

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Emanuel Rosonina, Akhi Akhter, Yimo Dou, John Babu & Veroni S. Sri Theivakadadcham. (2017) Regulation of transcription factors by sumoylation. Transcription 8:4, pages 220-231.
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Alvaro Valin & Grace Gill. (2013) Enforcing the pause: Transcription factor Sp3 limits productive elongation by RNA polymerase II. Cell Cycle 12:12, pages 1828-1834.
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Miia Rytinki, Sanna Kaikkonen, Päivi Sutinen, Ville Paakinaho, Vesa Rahkama & Jorma J. Palvimo. (2012) Dynamic SUMOylation Is Linked to the Activity Cycles of Androgen Receptor in the Cell Nucleus. Molecular and Cellular Biology 32:20, pages 4195-4205.
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Capucine Van Rechem, Gaylor Boulay, Sébastien Pinte, Nicolas Stankovic-Valentin, Cateline Guérardel & Dominique Leprince. (2010) Differential Regulation of HIC1 Target Genes by CtBP and NuRD, via an Acetylation/SUMOylation Switch, in Quiescent versus Proliferating Cells. Molecular and Cellular Biology 30:16, pages 4045-4059.
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Articles from other publishers (59)

Shawn M. Briley, Avery A. Ahmed, Tessa E. Steenwinkel, Peixin Jiang, Sean M. Hartig, Karen Schindler & Stephanie A. Pangas. (2023) Global SUMOylation in mouse oocytes maintains oocyte identity and regulates chromatin remodeling and transcriptional silencing at the end of folliculogenesis. Development 150:17.
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Bethany K. Patton, Surabhi Madadi, Shawn M. Briley, Avery A. Ahmed & Stephanie A. Pangas. (2023) Sumoylation regulates functional properties of the oocyte transcription factors SOHLH1 and NOBOX . The FASEB Journal 37:2.
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Xinyong Liu, Longwang Chen, Chen Zhang, Wei Dong, Hongbing Liu, Zhong Xiao, Kang Wang, Yaolu Zhang, Yahui Tang, Guangliang Hong, Zhongqiu Lu & Guangju Zhao. (2023) Ginkgolic acid promotes inflammation and macrophage apoptosis via SUMOylation and NF-κB pathways in sepsis. Frontiers in Medicine 9.
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Hong-Yeoul Ryu. (2022) SUMO pathway is required for ribosome biogenesis. BMB Reports 55:11, pages 535-540.
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Sushmitha Hegde, Ashley Sreejan, Chetan J Gadgil & Girish S Ratnaparkhi. (2022) SUMOylation of Dorsal attenuates Toll/NF-κB signaling. Genetics 221:3.
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Amarendranath Soory & Girish S. Ratnaparkhi. (2022) SUMOylation of Jun fine-tunes the Drosophila gut immune response. PLOS Pathogens 18:3, pages e1010356.
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Junya Zhang, Robert C. Augustine, Masaharu Suzuki, Juanjuan Feng, Si Nian Char, Bing Yang, Donald R. McCarty & Richard D. Vierstra. (2021) The SUMO ligase MMS21 profoundly influences maize development through its impact on genome activity and stability. PLOS Genetics 17:10, pages e1009830.
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Mohammad S. Baig, Yimo Dou, Benjamin G. Bergey, Russell Bahar, Justin M. Burgener, Marjan Moallem, James B. McNeil, Akhi Akhter, Giovanni L. Burke, Veroni S. Sri Theivakadadcham, Patricia Richard, Damien D’Amours & Emanuel Rosonina. (2021) Dynamic sumoylation of promoter-bound general transcription factors facilitates transcription by RNA polymerase II. PLOS Genetics 17:9, pages e1009828.
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Eric S. Lightcap, Pengfei Yu, Stephen GrossmanKeli SongMithun KhattarKristina Xega, Xingyue HeJames M. GavinHisashi Imaichi, James J. Garnsey, Erik Koenig, Hongru ZhangZhen LuPooja Shah, Yu Fu, Michael A. Milhollen, Beryl A. Hatton, Jessica RicebergVaishali Shinde, Cong LiJames Minissale, Xiaofeng Yang, Dylan England, Richard A. KlinghofferSteve Langston, Katherine GalvinGary ShapiroSai M. PulukuriSerge Y. Fuchs & Dennis Huszar. (2021) A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models. Science Translational Medicine 13:611.
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Takanobu Moriuchi & Fumiko Hirose. (2021) SUMOylation of RepoMan during late telophase regulates dephosphorylation of lamin A. Journal of Cell Science 134:17.
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Iman F. Fergani & Luciana R. Frick. (2021) Wrestling and Wrapping: A Perspective on SUMO Proteins in Schwann Cells. Biomolecules 11:7, pages 1055.
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Sina V Barysch, Nicolas Stankovic‐Valentin, Tim Miedema, Samir Karaca, Judith Doppel, Thiziri Nait Achour, Aarushi Vasudeva, Lucie Wolf, Carsten Sticht, Henning Urlaub & Frauke Melchior. (2021) Transient deSUMOylation of IRF2BP proteins controls early transcription in EGFR signaling. EMBO reports 22:3.
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Dipan Roy & Ari Sadanandom. (2021) SUMO mediated regulation of transcription factors as a mechanism for transducing environmental cues into cellular signaling in plants. Cellular and Molecular Life Sciences 78:6, pages 2641-2664.
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Mathias Boulanger, Mehuli Chakraborty, Denis Tempé, Marc Piechaczyk & Guillaume Bossis. (2021) SUMO and Transcriptional Regulation: The Lessons of Large-Scale Proteomic, Modifomic and Genomic Studies. Molecules 26:4, pages 828.
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P. VidhyasekaranP. Vidhyasekaran. 2020. Plant Innate Immunity Signals and Signaling Systems. Plant Innate Immunity Signals and Signaling Systems 169 221 .
Yu Peng, Zhenxing Wang, Zhiqiang Wang, Fang Yu, Jiwen Li & Jiemin Wong. (2019) SUMOylation down-regulates rDNA transcription by repressing expression of upstream-binding factor and proto-oncogene c-Myc. Journal of Biological Chemistry 294:50, pages 19155-19166.
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Chi-Hsien Wang, Pei-Wen Hung, Chi-Wu Chiang, Marc Lombès, Chang-Han Chen, Kuen-Haur Lee, Yu-Chih Lo, Mei-Hsiang Wu, Wen-Chang Chang & Ding-Yen Lin. (2019) Identification of two independent SUMO-interacting motifs in Fas-associated factor 1 (FAF1): Implications for mineralocorticoid receptor (MR)-mediated transcriptional regulation. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research 1866:8, pages 1282-1297.
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Shruti Srinivasan, Shilpa Rani Shankar, Yaju Wang & Reshma Taneja. (2019) SUMOylation of G9a regulates its function as an activator of myoblast proliferation. Cell Death & Disease 10:3.
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Fernando Rodríguez-Castañeda, Roza Berhanu Lemma, Ignacio Cuervo, Mads Bengtsen, Lisa Marie Moen, Marit Ledsaak, Ragnhild Eskeland & Odd Stokke Gabrielsen. (2018) The SUMO protease SENP1 and the chromatin remodeler CHD3 interact and jointly affect chromatin accessibility and gene expression. Journal of Biological Chemistry 293:40, pages 15439-15454.
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Weber Beringui Feitosa & Patricia L. Morris. (2018) SUMOylation regulates germinal vesicle breakdown and the Akt/PKB pathway during mouse oocyte maturation. American Journal of Physiology-Cell Physiology 315:1, pages C115-C121.
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Fang Yu, Guang Shi, Shimeng Cheng, Jiwei Chen, Shwu-Yuan Wu, Zhiqiang Wang, Nansong Xia, Yunhao Zhai, Zhenxing Wang, Yu Peng, Dong Wang, James X. Du, Lujian Liao, Sheng-Zhong Duan, Tieliu Shi, Jinke Cheng, Cheng-Ming Chiang, Jiwen Li & Jiemin Wong. (2018) SUMO suppresses and MYC amplifies transcription globally by regulating CDK9 sumoylation. Cell Research 28:6, pages 670-685.
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Hayeon Baik, Mathias Boulanger, Mohsen Hosseini, Julie Kowalczyk, Sonia Zaghdoudi, Tamara Salem, Jean-Emmanuel Sarry, Yosr Hicheri, Guillaume Cartron, Marc Piechaczyk & Guillaume Bossis. (2018) Targeting the SUMO Pathway Primes All- trans Retinoic Acid–Induced Differentiation of Nonpromyelocytic Acute Myeloid Leukemias . Cancer Research 78:10, pages 2601-2613.
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Muthu K. Shanmugam, Frank Arfuso, Surendar Arumugam, Arunachalam Chinnathambi, Bian Jinsong, Sudha Warrier, Ling Zhi Wang, Alan Prem Kumar, Kwang Seok Ahn, Gautam Sethi & Manikandan Lakshmanan. (2017) Role of novel histone modifications in cancer. Oncotarget 9:13, pages 11414-11426.
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Maki Komiya, Akihiro Ito, Mizuki Endo, Daisuke Hiruma, Mitsuru Hattori, Hisato Saitoh, Minoru Yoshida & Takeaki Ozawa. (2017) A genetic screen to discover SUMOylated proteins in living mammalian cells. Scientific Reports 7:1.
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David Wotton, Lucy F. Pemberton & Jacqueline Merrill-Schools. 2017. SUMO Regulation of Cellular Processes. SUMO Regulation of Cellular Processes 35 50 .
P. VidhyasekaranP. Vidhyasekaran. 2016. Switching on Plant Innate Immunity Signaling Systems. Switching on Plant Innate Immunity Signaling Systems 255 358 .
Patrick K. Nuro‐Gyina & Jeffrey D. Parvin. (2015) Roles for SUMO in pre‐ mRNA processing . WIREs RNA 7:1, pages 105-112.
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Hueng-Chuen Fan, Ching-Shiang Chi, Shin-Nan Cheng, Hsiu-Fen Lee, Jeng-Dau Tsai, Shinn-Zong Lin & Horng-Jyh Harn. (2015) Targeting New Candidate Genes by Small Molecules Approaching Neurodegenerative Diseases. International Journal of Molecular Sciences 17:1, pages 26.
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Koustav Sarkar, Sanjoy Sadhukhan, Seong-Su Han & Yatin M. Vyas. (2015) SUMOylation-disrupting WAS mutation converts WASp from a transcriptional activator to a repressor of NF-κB response genes in T cells. Blood 126:14, pages 1670-1682.
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Elisa Aguilar-MartinezXi ChenAaron WebberA. Paul MouldAnne Seifert, Ronald T. Hay & Andrew D. Sharrocks. (2015) Screen for multi-SUMO–binding proteins reveals a multi-SIM–binding mechanism for recruitment of the transcriptional regulator ZMYM2 to chromatin. Proceedings of the National Academy of Sciences 112:35.
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Tobias Wagner, Nicole Kiweler, Katharina Wolff, Shirley K. Knauer, André Brandl, Peter Hemmerich, Jan-Hermen Dannenberg, Thorsten Heinzel, Günter Schneider & Oliver H. Krämer. (2015) Sumoylation of HDAC2 promotes NF-κB-dependent gene expression. Oncotarget 6:9, pages 7123-7135.
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P. VidhyasekaranP. Vidhyasekaran. 2015. Plant Hormone Signaling Systems in Plant Innate Immunity. Plant Hormone Signaling Systems in Plant Innate Immunity 27 122 .
Dan Ben-Avraham. 2015. Longevity Genes. Longevity Genes 179 191 .
Ashley M. Fortress & Karyn M. Frick. (2014) Epigenetic regulation of estrogen-dependent memory. Frontiers in Neuroendocrinology 35:4, pages 530-549.
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Sabrina Fritah, Nouara Lhocine, Filip Golebiowski, Joëlle Mounier, Alexandra Andrieux, Grégory Jouvion, Ronald T Hay, Philippe Sansonetti & Anne Dejean. (2014) Sumoylation controls host anti‐bacterial response to the gut invasive pathogen Shigella flexneri . EMBO reports 15:9, pages 965-972.
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Ville Paakinaho, Sanna Kaikkonen, Harri Makkonen, Vladimir Benes & Jorma J. Palvimo. (2014) SUMOylation regulates the chromatin occupancy and anti-proliferative gene programs of glucocorticoid receptor. Nucleic Acids Research 42:3, pages 1575-1592.
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Fiona Gee, Kate Fisher, Ulrike Klemstein & Gino B. Poulin. (2013) An RNAi-Based Dimorphic Genetic Screen Identified the Double Bromodomain Protein BET-1 as a Sumo-Dependent Attenuator of RAS-Mediated Signalling. PLoS ONE 8:12, pages e83659.
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Juraj Bies, Marek Sramko & Linda Wolff. (2013) Stress-induced Phosphorylation of Thr486 in c-Myb by p38 Mitogen-activated Protein Kinases Attenuates Conjugation of SUMO-2/3. Journal of Biological Chemistry 288:52, pages 36983-36993.
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Nithya Raman, Arnab Nayak & Stefan Muller. (2013) The SUMO system: a master organizer of nuclear protein assemblies. Chromosoma 122:6, pages 475-485.
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Hélène Neyret-Kahn, Moussa Benhamed, Tao Ye, Stéphanie Le Gras, Jack-Christophe Cossec, Pierre Lapaquette, Oliver Bischof, Maia Ouspenskaia, Mary Dasso, Jacob Seeler, Irwin Davidson & Anne Dejean. (2013) Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation. Genome Research 23:10, pages 1563-1579.
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Rebecca R. Pferdehirt & Barbara J. Meyer. (2013) SUMOylation is essential for sex-specific assembly and function of the Caenorhabditis elegans dosage compensation complex on X chromosomes . Proceedings of the National Academy of Sciences 110:40.
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John W. Thompson, Kunjan R. Dave, Juan I. Young & Miguel A. Perez-Pinzon. (2013) Ischemic Preconditioning Alters the Epigenetic Profile of the Brain from Ischemic Intolerance to Ischemic Tolerance. Neurotherapeutics 10:4, pages 789-797.
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J Ding, Z-M Zhang, Y Xia, G-Q Liao, Y Pan, S Liu, Y Zhang & Z-S Yan. (2013) LSD1-mediated epigenetic modification contributes to proliferation and metastasis of colon cancer. British Journal of Cancer 109:4, pages 994-1003.
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Jocelyn Widagdo, Kylie M. Taylor, Peter W. Gunning, Edna C. Hardeman & Stephen J. Palmer. (2012) SUMOylation of GTF2IRD1 Regulates Protein Partner Interactions and Ubiquitin-Mediated Degradation. PLoS ONE 7:11, pages e49283.
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Hui-wen Liu, Jie Zhang, George F. Heine, Mansi Arora, Hatice Gulcin Ozer, Raghuram Onti-Srinivasan, Kun Huang & Jeffrey D. Parvin. (2012) Chromatin modification by SUMO-1 stimulates the promoters of translation machinery genes. Nucleic Acids Research 40:20, pages 10172-10186.
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André Brandl, Tobias Wagner, Katharina M. Uhlig, Shirley K. Knauer, Roland H. Stauber, Frauke Melchior, Günter Schneider, Thorsten Heinzel & Oliver H. Krämer. (2012) Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress. Journal of Molecular Cell Biology 4:5, pages 284-293.
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Pei-Chih Lee, Kimberly M. Taylor-Jaffe, Kara M. Nordin, Maneeshi S. Prasad, Rachel M. Lander & Carole LaBonne. (2012) SUMOylated SoxE factors recruit Grg4 and function as transcriptional repressors in the neural crest. Journal of Cell Biology 198:5, pages 799-813.
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Heisaburo Shindo, Rintaro Suzuki, Wataru Tsuchiya, Misako Taichi, Yuji Nishiuchi & Toshimasa Yamazaki. (2012) PHD finger of the SUMO ligase Siz/PIAS family in rice reveals specific binding for methylated histone H3 at lysine 4 and arginine 2. FEBS Letters 586:13, pages 1783-1789.
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Junbo Liu & Jun Ma. (2012) Drosophila Bicoid is a substrate of sumoylation and its activator function is subject to inhibition by this post‐translational modification . FEBS Letters 586:12, pages 1719-1723.
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María Ceballos-ChávezSabrina RiveroPablo García-Gutiérrez, Manuel Rodríguez-ParedesMario García-Domínguez, Shomi Bhattacharya & José C. Reyes. (2012) Control of neuronal differentiation by sumoylation of BRAF35, a subunit of the LSD1-CoREST histone demethylase complex. Proceedings of the National Academy of Sciences 109:21, pages 8085-8090.
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Julio C. Bayona, Ernesto S. Nakayasu, Marc Laverrière, Clemente Aguilar, Tiago J.P. Sobreira, Hyungwon Choi, Alexey I. Nesvizhskii, Igor C. Almeida, Juan J. Cazzulo & Vanina E. Alvarez. (2011) SUMOylation Pathway in Trypanosoma cruzi: Functional Characterization and Proteomic Analysis of Target Proteins. Molecular & Cellular Proteomics 10:12, pages M110.007369.
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Jun Ma. (2011) Transcriptional activators and activation mechanisms. Protein & Cell 2:11, pages 879-888.
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Eckardt Treuter & Nicolas Venteclef. (2011) Transcriptional control of metabolic and inflammatory pathways by nuclear receptor SUMOylation. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1812:8, pages 909-918.
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Michaela Petter, Chin Chin Lee, Timothy J. Byrne, Katja E. Boysen, Jennifer Volz, Stuart A. Ralph, Alan F. Cowman, Graham V. Brown & Michael F. Duffy. (2011) Expression of P. falciparum var Genes Involves Exchange of the Histone Variant H2A.Z at the Promoter. PLoS Pathogens 7:2, pages e1001292.
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Luciano Pirola, Aneta Balcerczyk, Jun Okabe & Assam El-Osta. (2010) Epigenetic phenomena linked to diabetic complications. Nature Reviews Endocrinology 6:12, pages 665-675.
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Ann-Kristin Molværsmyr, Thomas Sæther, Siv Gilfillan, Petra Isabel Lorenzo, Heidi Kvaløy, Vilborg Matre & Odd Stokke Gabrielsen. (2010) A SUMO-regulated activation function controls synergy of c-Myb through a repressor–activator switch leading to differential p300 recruitment. Nucleic Acids Research 38:15, pages 4970-4984.
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Jun WangRobert J. Schwartz. (2010) Sumoylation and Regulation of Cardiac Gene Expression. Circulation Research 107:1, pages 19-29.
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Emanuel Rosonina, Sarah M. Duncan & James L. Manley. (2010) SUMO functions in constitutive transcription and during activation of inducible genes in yeast. Genes & Development 24:12, pages 1242-1252.
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Astrid Jüngel, Caroline Ospelt & Steffen Gay. (2010) What can we learn from epigenetics in the year 2009?. Current Opinion in Rheumatology 22:3, pages 284-292.
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