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Special Focus Short Report

Antibody persistence and immune memory 15 months after priming with an investigational tetravalent meningococcal tetanus toxoid conjugate vaccine (MenACWY-TT) in toddlers and young children

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Pages 866-872 | Received 17 Feb 2012, Accepted 02 Apr 2012, Published online: 09 Apr 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (6)

Beatriz P. Quiambao, Ashish Bavdekar, Anand Prakash Dubey, Hemant Jain, Devayani Kolhe, Véronique Bianco, Jacqueline M. Miller & Marie Van der Wielen. (2017) Antibody persistence up to 5 y after vaccination with a quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine in adolescents. Human Vaccines & Immunotherapeutics 13:3, pages 636-644.
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Beatriz P. Quiambao, Hermant Jain, Ashish Bavdekar, Anand Prakash Dubey, Devayani Kolhe, Véronique Bianco, Marie Van der Wielen & Jacqueline M. Miller. (2016) Persistence of the immune response two years after vaccination with quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine (MenACWY-TT) in Asian adolescents. Human Vaccines & Immunotherapeutics 12:8, pages 2162-2168.
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Timo Vesikari, Aino Forsten, Veronique Bianco, Marie Van der Wielen & Jacqueline M Miller. (2016) Antibody persistence up to 5 years after vaccination of toddlers and children between 12 months and 10 years of age with a quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine. Human Vaccines & Immunotherapeutics 12:1, pages 132-139.
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Carine P Hedari, Rima W Khinkarly & Ghassan S Dbaibo. (2014) Meningococcal serogroups A, C, W-135, and Y tetanus toxoid conjugate vaccine: a new conjugate vaccine against invasive meningococcal disease. Infection and Drug Resistance 7, pages 85-99.
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Soha Ghanem, Sara Hassan, Randa Saad & Ghassan S Dbaibo. (2013) Quadrivalent meningococcal serogroups A, C, W, and Y tetanus toxoid conjugate vaccine (MenACWY-TT): a review. Expert Opinion on Biological Therapy 13:8, pages 1197-1205.
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Articles from other publishers (19)

Christine S. Rollier, Christina Dold, Luke Blackwell, Aline Linder, Laura Silva-Reyes, Elizabeth Clutterbuck, Kimberly Davis, Karen Ford, Xinxue Liu, Ann Holland, Hannah Chan, Holly Harbinson, Daniel O'Connor, Ray Borrow, Matthew D. Snape & Andrew J. Pollard. (2022) Immunogenicity of a single 4CMenB vaccine booster in adolescents 11 years after childhood immunisation. Vaccine 40:32, pages 4453-4463.
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Chris Webber, Paula Peyrani, Paul Balmer & Lidia Serra. (2020) Persistence of bactericidal antibodies following primary and booster MenACWY-TT vaccination of toddlers: A review of clinical studies. Vaccine 38:27, pages 4236-4245.
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Jose Manuel Merino Arribas, Alfonso Carmona Martínez, Michael Horn, Xavier Maria Perez Porcuna, Maria del Carmen Otero Reigada, Josep Marès Bermúdez, Fernando Centeno Malfaz, Mariano Miranda, Maria Mendez, Miguel Angel Garcia Cabezas, Wittermann Christoph, Gerhard Bleckmann, Thomas Fischbach, Devayani Kolhe, Marie Van der Wielen & Yaela Baine. (2018) Immunogenicity and Reactogenicity of DTPa-HBV-IPV/Hib and PHiD-CV When Coadministered With MenACWY-TT in Infants. Pediatric Infectious Disease Journal 37:7, pages 704-714.
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Clare L. Cutland, Terry Nolan, Scott A. Halperin, Zafer Kurugol, Khatija Ahmed, Kirsten P. Perrett, Peter Richmond, Helen S Marshall, Mehmet Ceyhan, Devayani Kolhe, Marjan Hezareh & Marie Van Der Wielen. (2018) Immunogenicity and safety of one or two doses of the quadrivalent meningococcal vaccine MenACWY-TT given alone or with the 13-valent pneumococcal conjugate vaccine in toddlers: A phase III, open-label, randomised study. Vaccine 36:14, pages 1908-1916.
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Sohita Dhillon & David Pace. (2017) Meningococcal Quadrivalent Tetanus Toxoid Conjugate Vaccine (MenACWY-TT; Nimenrix®): A Review. Drugs 77:17, pages 1881-1896.
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Jose Manuel Merino Arribas, Alfonso Carmona Martínez, Michael Horn, Xavier Maria Perez Porcuna, Maria del Carmen Otero Reigada, Josep Marès Bermúdez, Fernando Centeno Malfaz, Mariano Miranda, Maria Mendez, Miguel Angel Garcia Cabezas, Christoph Wittermann, Gerhard Bleckmann, Thomas Fischbach, Devayani Kolhe, Marie van der Wielen & Yaela Baine. (2017) Safety and Immunogenicity of the Quadrivalent Meningococcal Serogroups A, C, W and Y Tetanus Toxoid Conjugate Vaccine Coadministered With Routine Childhood Vaccines in European Infants. Pediatric Infectious Disease Journal 36:4, pages e98-e107.
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Nicola P. Klein, Yaela Baine, Devayani Kolhe, Carmen I. Baccarini, Jacqueline M. Miller & Marie Van der Wielen. (2016) Five-year Antibody Persistence and Booster Response After 1 or 2 Doses of Meningococcal A, C, W and Y Tetanus Toxoid Conjugate Vaccine in Healthy Children. The Pediatric Infectious Disease Journal 35:6, pages 662-672.
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William Johnston, Brandon Essink, Judith Kirstein, Eduardo Forleo-Neto, Sandra Percell, Linda Han, Pavitra Keshavan & Igor Smolenov. (2016) Comparative Assessment of a Single Dose and a 2-dose Vaccination Series of a Quadrivalent Meningococcal CRM-conjugate Vaccine (MenACWY-CRM) in Children 2–10 Years of Age. Pediatric Infectious Disease Journal 35:1, pages e19-e27.
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Charissa Fay Corazon Borja-Tabora, Cecilia Montalban, Ziad A. Memish, Dominique Boutriau, Devayani Kolhe, Jacqueline M. Miller & Marie Van der Wielen. (2015) Long-term immunogenicity and safety after a single dose of the quadrivalent meningococcal serogroups A, C, W, and Y tetanus toxoid conjugate vaccine in adolescents and adults: 5-year follow-up of an open, randomized trial. BMC Infectious Diseases 15:1.
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Timo Vesikari, Aino Forsten, Veronique Bianco, Marie Van der Wielen & Jacqueline M. Miller. (2015) Immunogenicity, Safety and Antibody Persistence of a Booster Dose of Quadrivalent Meningococcal ACWY-tetanus Toxoid Conjugate Vaccine Compared with Monovalent Meningococcal Serogroup C Vaccine Administered Four Years After Primary Vaccination Using the Same Vaccines. Pediatric Infectious Disease Journal 34:12, pages e298-e307.
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Roger Baxter, Yaela Baine, Devayani Kolhe, Carmen I. Baccarini, Jacqueline M. Miller & Marie Van der Wielen. (2015) Five-year Antibody Persistence and Booster Response to a Single Dose of Meningococcal A, C, W and Y Tetanus Toxoid Conjugate Vaccine in Adolescents and Young Adults. Pediatric Infectious Disease Journal 34:11, pages 1236-1243.
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Paolo Pellegrino, Valentina Perrone, Sonia Radice, Annalisa Capuano & Emilio Clementi. (2015) Immunogenicity of meningococcal quadrivalent (serogroup A, C, W135 and Y) tetanus toxoid conjugate vaccine: Systematic review and meta-analysis. Pharmacological Research 92, pages 31-39.
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Markus Knuf. (2014) Weitreichende Möglichkeiten der Impfprävention. Pädiatrie 26:S1, pages 20-27.
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Timo Vesikari, Aino Forsten, Veronique Bianco, Marie Van der Wielen & Jacqueline M. Miller. (2014) Antibody persistence to meningococcal serogroups A, C, W and Y in toddlers two years after vaccination with a quadrivalent meningococcal ACWY-tetanus toxoid conjugate (MenACWY-TT) vaccine as measured by bactericidal antibody assays using rabbit or human complement. Trials in Vaccinology 3, pages 121-126.
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M. Knuf & U. Vogel. (2013) Meningokokkenimpfungen. Monatsschrift Kinderheilkunde 161:12, pages 1146-1153.
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Nicola P. Klein, Yaela Baine, Veronique Bianco, Pascal R. Lestrate, Aftab Naz, Mark Blatter, Leonard R. Friedland & Jacqueline M. Miller. (2013) One or Two Doses of Quadrivalent Meningococcal Serogroups A, C, W-135 and Y Tetanus Toxoid Conjugate Vaccine Is Immunogenic in 9- to 12-Month-Old Children. Pediatric Infectious Disease Journal 32:7, pages 760-767.
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Lisa K. McNeil, Robert J. Zagursky, Shuo L. Lin, Ellen Murphy, Gary W. Zlotnick, Susan K. Hoiseth, Kathrin U. Jansen & Annaliesa S. Anderson. (2013) Role of Factor H Binding Protein in Neisseria meningitidis Virulence and Its Potential as a Vaccine Candidate To Broadly Protect against Meningococcal Disease. Microbiology and Molecular Biology Reviews 77:2, pages 234-252.
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Helen Findlow & Ray Borrow. (2013) Immunogenicity and Safety of a Meningococcal Serogroup A, C, Y and W Glycoconjugate Vaccine, ACWY-TT. Advances in Therapy 30:5, pages 431-458.
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Jamie D. Croxtall & Sohita Dhillon. (2012) Meningococcal Quadrivalent (Serogroups A, C, W135 and Y) Tetanus Toxoid Conjugate Vaccine (Nimenrix™). Drugs 72:18, pages 2407-2430.
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