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Research Paper

A randomized study to assess the immunogenicity, antibody persistence and safety of a tetravalent meningococcal serogroups A, C, W-135 and Y tetanus toxoid conjugate vaccine in children aged 2–10 years

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Pages 1882-1891 | Received 15 Jun 2012, Accepted 11 Sep 2012, Published online: 02 Oct 2012

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Read on this site (10)

Timo Vesikari, Paula Peyrani, Chris Webber, Marie Van Der Wielen, Brigitte Cheuvart, Nathalie De Schrevel, Emmanuel Aris, Mark Cutler, Ping Li & John L. Perez. (2020) Ten-Year Antibody Persistence and Booster Response to MenACWY-TT Vaccine After Primary Vaccination at 1-10 Years of Age. Human Vaccines & Immunotherapeutics 16:6, pages 1280-1291.
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Jamie Findlow, Paul Balmer & Ray Borrow. (2019) A review of complement sources used in serum bactericidal assays for evaluating immune responses to meningococcal ACWY conjugate vaccines. Human Vaccines & Immunotherapeutics 15:10, pages 2491-2500.
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Erman Tritama, Catur Riani, Indra Rudiansyah, Arip Hidayat, Siti Azizah Kharisnaeni & Debbie Sofie Retnoningrum. (2018) Evaluation of alum-based adjuvant on the immunogenicity of salmonella enterica serovar typhi conjugates vaccines. Human Vaccines & Immunotherapeutics 14:6, pages 1524-1529.
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Giulia Piccini, Alessandro Torelli, Elena Gianchecchi, Simona Piccirella & Emanuele Montomoli. (2016) Fighting Neisseria meningitidis: past and current vaccination strategies. Expert Review of Vaccines 15:11, pages 1393-1407.
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Beatriz P. Quiambao, Hermant Jain, Ashish Bavdekar, Anand Prakash Dubey, Devayani Kolhe, Véronique Bianco, Marie Van der Wielen & Jacqueline M. Miller. (2016) Persistence of the immune response two years after vaccination with quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine (MenACWY-TT) in Asian adolescents. Human Vaccines & Immunotherapeutics 12:8, pages 2162-2168.
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Timo Vesikari, Aino Forsten, Veronique Bianco, Marie Van der Wielen & Jacqueline M Miller. (2016) Antibody persistence up to 5 years after vaccination of toddlers and children between 12 months and 10 years of age with a quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine. Human Vaccines & Immunotherapeutics 12:1, pages 132-139.
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Marco Aurélio Sáfadi, Julie A Bettinger, Gabriela Moreno Maturana, Godwin Enwere & Ray Borrow. (2015) Evolving meningococcal immunization strategies. Expert Review of Vaccines 14:4, pages 505-517.
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Carine P Hedari, Rima W Khinkarly & Ghassan S Dbaibo. (2014) Meningococcal serogroups A, C, W-135, and Y tetanus toxoid conjugate vaccine: a new conjugate vaccine against invasive meningococcal disease. Infection and Drug Resistance 7, pages 85-99.
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Michael E Pichichero. (2013) Protein carriers of conjugate vaccines. Human Vaccines & Immunotherapeutics 9:12, pages 2505-2523.
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Articles from other publishers (16)

Lidia Serra, Chris Webber, Cindy Burman, Patrizia Bueti, Maria Gorruso & Susan Mather. (2022) Clinical trial and postmarketing safety experience with MenACWY-TT, a meningococcal group A, C, W, and Y tetanus conjugate vaccine. Vaccine 40:49, pages 7014-7021.
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Chris Webber, Paula Peyrani, Paul Balmer & Lidia Serra. (2020) Persistence of bactericidal antibodies following primary and booster MenACWY-TT vaccination of toddlers: A review of clinical studies. Vaccine 38:27, pages 4236-4245.
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Jessica Presa, Jamie Findlow, Jelena Vojicic, Scott Williams & Lidia Serra. (2019) Epidemiologic Trends, Global Shifts in Meningococcal Vaccination Guidelines, and Data Supporting the Use of MenACWY-TT Vaccine: A Review. Infectious Diseases and Therapy 8:3, pages 307-333.
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Jamie Findlow & Markus Knuf. (2019) Immunogenicity and safety of meningococcal group A, C, W and Y tetanus toxoid conjugate vaccine: review of clinical and real-world evidence. Future Microbiology 14:7, pages 563-580.
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Luis Rivera, Tino F. Schwarz, Kyung-Hyo Kim, Yun-Kyung Kim, Ulrich Behre, Sung-Ho Cha, Dae Sun Jo, Jacob Lee, Jin-Soo Lee, Brigitte Cheuvart, Archana Jastorff & Marie Van der Wielen. (2018) Immunogenicity and safety of the quadrivalent meningococcal vaccine MenACWY-TT co-administered with a combined diphtheria-tetanus-acellular pertussis vaccine versus their separate administration in adolescents and young adults: A phase III, randomized study. Vaccine 36:31, pages 4750-4758.
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Markus Knuf, Klaus Helm, Devayani Kolhe, Marie Van Der Wielen & Yaela Baine. (2018) Antibody persistence and booster response 68 months after vaccination at 2–10 years of age with one dose of MenACWY-TT conjugate vaccine. Vaccine 36:23, pages 3286-3295.
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Nicola P. Klein, Tomas Habanec, Pavel Kosina, Nirmish R. Shah, Devayani Kolhe, Jacqueline M. Miller, Marjan Hezareh & Marie Van der Wielen. (2018) Immunogenicity and safety of the quadrivalent meningococcal ACWY-tetanus toxoid conjugate vaccine (MenACWY-TT) in splenectomized or hyposplenic children and adolescents: Results of a phase III, open, non-randomized study. Vaccine 36:17, pages 2356-2363.
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Jose Manuel Merino Arribas, Alfonso Carmona Martínez, Michael Horn, Xavier Maria Perez Porcuna, Maria del Carmen Otero Reigada, Josep Marès Bermúdez, Fernando Centeno Malfaz, Mariano Miranda, Maria Mendez, Miguel Angel Garcia Cabezas, Christoph Wittermann, Gerhard Bleckmann, Thomas Fischbach, Devayani Kolhe, Marie van der Wielen & Yaela Baine. (2017) Safety and Immunogenicity of the Quadrivalent Meningococcal Serogroups A, C, W and Y Tetanus Toxoid Conjugate Vaccine Coadministered With Routine Childhood Vaccines in European Infants. Pediatric Infectious Disease Journal 36:4, pages e98-e107.
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Nicola P. Klein, Yaela Baine, Devayani Kolhe, Carmen I. Baccarini, Jacqueline M. Miller & Marie Van der Wielen. (2016) Five-year Antibody Persistence and Booster Response After 1 or 2 Doses of Meningococcal A, C, W and Y Tetanus Toxoid Conjugate Vaccine in Healthy Children. The Pediatric Infectious Disease Journal 35:6, pages 662-672.
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William Johnston, Brandon Essink, Judith Kirstein, Eduardo Forleo-Neto, Sandra Percell, Linda Han, Pavitra Keshavan & Igor Smolenov. (2016) Comparative Assessment of a Single Dose and a 2-dose Vaccination Series of a Quadrivalent Meningococcal CRM-conjugate Vaccine (MenACWY-CRM) in Children 2–10 Years of Age. Pediatric Infectious Disease Journal 35:1, pages e19-e27.
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Charissa Fay Corazon Borja-Tabora, Cecilia Montalban, Ziad A. Memish, Dominique Boutriau, Devayani Kolhe, Jacqueline M. Miller & Marie Van der Wielen. (2015) Long-term immunogenicity and safety after a single dose of the quadrivalent meningococcal serogroups A, C, W, and Y tetanus toxoid conjugate vaccine in adolescents and adults: 5-year follow-up of an open, randomized trial. BMC Infectious Diseases 15:1.
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Timo Vesikari, Aino Forsten, Veronique Bianco, Marie Van der Wielen & Jacqueline M. Miller. (2015) Immunogenicity, Safety and Antibody Persistence of a Booster Dose of Quadrivalent Meningococcal ACWY-tetanus Toxoid Conjugate Vaccine Compared with Monovalent Meningococcal Serogroup C Vaccine Administered Four Years After Primary Vaccination Using the Same Vaccines. Pediatric Infectious Disease Journal 34:12, pages e298-e307.
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Roger Baxter, Yaela Baine, Devayani Kolhe, Carmen I. Baccarini, Jacqueline M. Miller & Marie Van der Wielen. (2015) Five-year Antibody Persistence and Booster Response to a Single Dose of Meningococcal A, C, W and Y Tetanus Toxoid Conjugate Vaccine in Adolescents and Young Adults. Pediatric Infectious Disease Journal 34:11, pages 1236-1243.
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E.D.G. McIntosh, M. Bröker, J. Wassil, J.A. Welsch & R. Borrow. (2015) Serum bactericidal antibody assays – The role of complement in infection and immunity. Vaccine 33:36, pages 4414-4421.
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Paolo Pellegrino, Valentina Perrone, Sonia Radice, Annalisa Capuano & Emilio Clementi. (2015) Immunogenicity of meningococcal quadrivalent (serogroup A, C, W135 and Y) tetanus toxoid conjugate vaccine: Systematic review and meta-analysis. Pharmacological Research 92, pages 31-39.
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Helen Findlow & Ray Borrow. (2013) Immunogenicity and Safety of a Meningococcal Serogroup A, C, Y and W Glycoconjugate Vaccine, ACWY-TT. Advances in Therapy 30:5, pages 431-458.
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