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Special Focus Commentary

Dengue human infection model

Re-establishing a tool for understanding dengue immunology and advancing vaccine development

Pages 1587-1590 | Received 20 Feb 2013, Accepted 04 Mar 2013, Published online: 06 Mar 2013

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Adam T Waickman, Krista Newell, Timothy P Endy & Stephen J Thomas. (2023) Biologics for dengue prevention: up-to-date. Expert Opinion on Biological Therapy 23:1, pages 73-87.
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Scott B. Halstead & David W. Vaughn. 2023. Plotkin's Vaccines. Plotkin's Vaccines 275 285.e6 .
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Robert K. M. Choy, A. Louis Bourgeois, Christian F. Ockenhouse, Richard I. Walker, Rebecca L. Sheets & Jorge Flores. (2022) Controlled Human Infection Models To Accelerate Vaccine Development. Clinical Microbiology Reviews 35:3.
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Timothy P Endy, Dongliang Wang, Mark E Polhemus, Richard G Jarman, Louis E Jasper, Greg Gromowski, Leyi Lin, Rafael A De La Barra, Heather Friberg, Jeffrey R Currier, Mark Abbott, Lisa Ware, Michelle Klick, Kristopher M Paolino, Donald C Blair, Kenneth Eckels, Wiriya Rutvisuttinunt & Stephen J Thomas. (2021) A Phase 1, Open-Label Assessment of a Dengue Virus-1 Live Virus Human Challenge Strain. The Journal of Infectious Diseases 223:2, pages 258-267.
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Christine A. King, Adam D. Wegman & Timothy P. Endy. (2020) Mobilization and Activation of the Innate Immune Response to Dengue Virus. Frontiers in Cellular and Infection Microbiology 10.
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Bruno Guy, Eng Eong Ooi, Jose Ramos-Castañeda & Stephen J. Thomas. (2020) When Can One Vaccinate with a Live Vaccine after Wild-Type Dengue Infection?. Vaccines 8:2, pages 174.
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Scott B. Halstead. (2018) Insights from direct studies on human dengue infections. Proceedings of the National Academy of Sciences 116:1, pages 17-19.
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Kathryn B Anderson, Timothy P Endy & Stephen J Thomas. (2018) The dynamic role of dengue cross-reactive immunity: changing the approach to defining vaccine safety and efficacy. The Lancet Infectious Diseases 18:10, pages e333-e338.
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Bouchra Kitab, Michinori Kohara & Kyoko Tsukiyama-Kohara. (2018) Experimental in vitro and in vivo systems for studying the innate immune response during dengue virus infections. Archives of Virology 163:7, pages 1717-1726.
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Scott B. Halstead & Stephen J. Thomas. 2018. Plotkin's Vaccines. Plotkin's Vaccines 241 251.e6 .
Irfan A. Rather, Hilal A. Parray, Jameel B. Lone, Woon K. Paek, Jeongheui Lim, Vivek K. Bajpai & Yong-Ha Park. (2017) Prevention and Control Strategies to Counter Dengue Virus Infection. Frontiers in Cellular and Infection Microbiology 7.
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Suzanne JF Kaptein & Johan Neyts. (2016) Towards antiviral therapies for treating dengue virus infections. Current Opinion in Pharmacology 30, pages 1-7.
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Bruno GuyJean LangMelanie SavilleNicholas Jackson. (2016) Vaccination Against Dengue: Challenges and Current Developments. Annual Review of Medicine 67:1, pages 387-404.
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Bruno Guy, Olivier Briand, Jean Lang, Melanie Saville & Nicholas Jackson. (2015) Development of the Sanofi Pasteur tetravalent dengue vaccine: One more step forward. Vaccine 33:50, pages 7100-7111.
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Kitti Wing Ki Chan, Satoru Watanabe, Ranmali Kavishna, Sylvie Alonso & Subhash G. Vasudevan. (2015) Animal models for studying dengue pathogenesis and therapy. Antiviral Research 123, pages 5-14.
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David L. Evers, Carol B. Fowler, Jeffrey T. Mason & Rebecca K. Mimnall. (2014) Deliberate Microbial Infection Research Reveals Limitations to Current Safety Protections of Healthy Human Subjects. Science and Engineering Ethics 21:4, pages 1049-1064.
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Louis Lambrechts, Neil M Ferguson, Eva Harris, Edward C Holmes, Elizabeth A McGraw, Scott L O'Neill, Eng E Ooi, Scott A Ritchie, Peter A Ryan, Thomas W Scott, Cameron P Simmons & Scott C Weaver. (2015) Assessing the epidemiological effect of wolbachia for dengue control. The Lancet Infectious Diseases 15:7, pages 862-866.
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Thomas C Darton, Christoph J Blohmke, Vasee S Moorthy, Daniel M Altmann, Frederick G Hayden, Elizabeth A Clutterbuck, Myron M Levine, Adrian V S Hill & Andrew J Pollard. (2015) Design, recruitment, and microbiological considerations in human challenge studies. The Lancet Infectious Diseases 15:7, pages 840-851.
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Eng Eong Ooi, Benjamin Haaland, Duane J. Gubler & Grace E. Snow. (2014) Research on Dengue During World War II Revisited. The American Journal of Tropical Medicine and Hygiene 91:6, pages 1203-1217.
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James Whitehorn, Sophie Yacoub, Katherine L. Anders, Louis R. Macareo, M. Cristina Cassetti, Vinh Chau Nguyen Van, Pei-Yong Shi, Bridget Wills & Cameron P. Simmons. (2014) Dengue Therapeutics, Chemoprophylaxis, and Allied Tools: State of the Art and Future Directions. PLoS Neglected Tropical Diseases 8:8, pages e3025.
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A. L. Rothman. (2014) DHIM Supporting Immunologic Investigations and the Identification of Immune Correlates of Protection. Journal of Infectious Diseases 209:suppl 2, pages S61-S65.
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C. N. Mores, R. C. Christofferson & S. A. Davidson. (2014) The Role of the Mosquito in a Dengue Human Infection Model. Journal of Infectious Diseases 209:suppl 2, pages S71-S78.
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Mark K. Slifka. (2014) Vaccine-Mediated Immunity Against Dengue and the Potential for Long-Term Protection Against Disease. Frontiers in Immunology 5.
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M. Cristina Cassetti & Scott B. Halstead. (2014) Consultation on dengue vaccines: Progress in understanding protection, 26?28 June 2013, Rockville, Maryland. Vaccine 32:26, pages 3115-3121.
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Stephen J. Thomas, Timothy P. Endy & Alan L. Rothman. 2014. Viral Infections of Humans. Viral Infections of Humans 351 381 .

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