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Commentary

Progress on the research and development of inactivated EV71 whole-virus vaccines

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Pages 1701-1705 | Received 23 Apr 2013, Accepted 06 May 2013, Published online: 06 Jun 2013

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Read on this site (6)

Yang Zhou, Jing-Xin Li, Peng-Fei Jin, Yu-Xiao Wang & Feng-Cai Zhu. (2016) Enterovirus 71: a whole virion inactivated enterovirus 71 vaccine. Expert Review of Vaccines 15:7, pages 803-813.
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Wei Zhang, Yujia Kong, Zhiwei Jiang, Chanjuan Li, Ling Wang & Jielai Xia. (2016) Comprehensive safety assessment of a human inactivated diploid enterovirus 71 vaccine based on a phase III clinical trial. Human Vaccines & Immunotherapeutics 12:4, pages 922-930.
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Xue Han, Xiao-ling Ying, Shi-li Zhou, Tao Han, Hao Huang, Qi Jin, Fan Yang, Qi-ying Sun & Xian-xun Sun. (2014) Characterization of the enterovirus 71 P1 polyprotein expressed in Pichia pastor as a candidate vaccine. Human Vaccines & Immunotherapeutics 10:8, pages 2220-2226.
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Yi-Juan Chen, Fan-Yue Meng, Qunying Mao, Jing-Xin Li, Hua Wang, Zheng-Lun Liang, Yun-Tao Zhang, Fan Gao, Qing-Hua Chen, Yuemei Hu, Zi-Jun Ge, Xin Yao, Hui-Jie Guo, Feng-Cai Zhu & Xiu-Ling Li. (2014) Clinical evaluation for batch consistency of an inactivated enterovirus 71 vaccine in a large-scale phase 3 clinical trial. Human Vaccines & Immunotherapeutics 10:5, pages 1366-1372.
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Jing-Xin Li, Qun-Ying Mao, Zheng-Lun Liang, Hong Ji & Feng-Cai Zhu. (2014) Development of enterovirus 71 vaccines: from the lab bench to Phase III clinical trials. Expert Review of Vaccines 13:5, pages 609-618.
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Jing-Xin Li, Fan-Yue Meng, Zhenglun Liang, Qunying Mao & Feng-Cai Zhu. (2014) How to understand the efficacy measurements for enterovirus type 71 vaccine?. Human Vaccines & Immunotherapeutics 10:3, pages 623-627.
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Zhenglun Liang & Junzhi Wang. (2014) EV71 vaccine, an invaluable gift for children. Clinical & Translational Immunology 3:10, pages e28.
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Stanley Plotkin. (2014) History of vaccination. Proceedings of the National Academy of Sciences 111:34, pages 12283-12287.
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Tao Meng & Jimmy Kwang. (2014) Attenuation of Human Enterovirus 71 High-Replication-Fidelity Variants in AG129 Mice. Journal of Virology 88:10, pages 5803-5815.
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Crossref
Wei Li, Lina Yi, Juan Su, Jing Lu, Changwen Ke, Hanri Zeng, Dawei Guan, Cong Ma, Wanly Zhang, Hong Xiao, Hui Li, Jinyan Lin & Yonghui Zhang. (2013) Seroprevalence of Human Enterovirus 71 and Coxsackievirus A16 in Guangdong, China, in Pre- and Post-2010 HFMD Epidemic Period. PLoS ONE 8:12, pages e80515.
Crossref
Hui Zhao, Hao-Yang Li, Jian-Feng Han, Yong-Qiang Deng, Yue-Xiang Li, Shun-Ya Zhu, Ya-Ling He, E-De Qin, Rong Chen & Cheng-Feng Qin. (2013) Virus-like particles produced in Saccharomyces cerevisiae elicit protective immunity against Coxsackievirus A16 in mice. Applied Microbiology and Biotechnology 97:24, pages 10445-10452.
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