Advanced search
Publication Cover
Human Vaccines & Immunotherapeutics Volume 10, 2014 - Issue 7
Submit an article Journal homepage
1,902
Views
39
CrossRef citations to date
0
Altmetric
Research Paper

Immune responses elicited against rotavirus middle layer protein VP6 inhibit viral replication in vitro and in vivo

Suvi Lappalainen Vaccine Research Center; School of Medicine; University of Tampere; Tampere, FinlandCorrespondence[email protected]
,
Ana Ruth Pastor Instituto de Biotecnología; Universidad Nacional Autónoma de México; Cuernavaca, Morelos, México
,
Kirsi Tamminen Vaccine Research Center; School of Medicine; University of Tampere; Tampere, Finland
,
Vanessa López-Guerrero Facultad de Medicina; Universidad Autónoma del Estado de Morelos; Cuernavaca, Morelos, México
,
Fernando Esquivel-Guadarrama Facultad de Medicina; Universidad Autónoma del Estado de Morelos; Cuernavaca, Morelos, México
,
Laura A Palomares Instituto de Biotecnología; Universidad Nacional Autónoma de México; Cuernavaca, Morelos, México
,
Timo Vesikari Vaccine Research Center; School of Medicine; University of Tampere; Tampere, Finland
&
Vesna Blazevic Vaccine Research Center; School of Medicine; University of Tampere; Tampere, Finland
 show all
Pages 2039-2047 | Received 13 Jan 2014, Accepted 11 Apr 2014, Published online: 29 Apr 2014

Citations (39)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (4)

Volker Vetter, Robert C. Gardner, Serge Debrus, Bernd Benninghoff & Priya Pereira. (2022) Established and new rotavirus vaccines: a comprehensive review for healthcare professionals. Human Vaccines & Immunotherapeutics 18:1.
Read now
Annika Skansberg, Molly Sauer, Marissa Tan, Mathuram Santosham & Mary Carol Jennings. (2021) Product review of the rotavirus vaccines ROTASIIL, ROTAVAC, and Rotavin-M1. Human Vaccines & Immunotherapeutics 17:4, pages 1223-1234.
Read now
Vesna Blazevic, Maria Malm, Daisuke Arinobu, Suvi Lappalainen & Timo Vesikari. (2016) Rotavirus capsid VP6 protein acts as an adjuvant in vivo for norovirus virus-like particles in a combination vaccine. Human Vaccines & Immunotherapeutics 12:3, pages 740-748.
Read now
Frank Sainsbury. (2014) Meeting Report VLPNPV: Sessions 1 and 2: Plenary. Human Vaccines & Immunotherapeutics 10:10, pages 3060-3063.
Read now

Articles from other publishers (35)

Stanley A. Plotkin & Peter B. Gilbert. 2023. Plotkin's Vaccines. Plotkin's Vaccines 45 51.e5 .
Deepak Kumar, Frances K Shepherd, Nora L. Springer, Waithaka Mwangi & Douglas G. Marthaler. (2022) Rotavirus Infection in Swine: Genotypic Diversity, Immune Responses, and Role of Gut Microbiome in Rotavirus Immunity. Pathogens 11:10, pages 1078.
Crossref
Annamalai RamaAnuja PaiDivya Rosa BarretoSiva Kumar KannanAnup Naha. (2022) Virus-Like particles as a Novel Targeted Drug Delivery Platform for Biomedical Applications. Research Journal of Pharmacy and Technology, pages 2801-2808.
Crossref
Zabihollah Shoja, Somayeh Jalilvand, Tayebeh Latifi & Farzin Roohvand. (2022) Rotavirus VP6: involvement in immunogenicity, adjuvant activity, and use as a vector for heterologous peptides, drug delivery, and production of nano-biomaterials. Archives of Virology 167:4, pages 1013-1023.
Crossref
Atefeh Afchangi, Somayeh Jalilvand, Arash Arashkia, Tayebeh Latifi, Mohammad Farahmand, Maryam Mashhadi Abolghasem Shirazi, Seyed Dawood Mousavi Nasab, Sayed Mahdi Marashi, Farzin Roohvand & Zabihollah Shoja. (2022) Co-administration of rotavirus nanospheres VP6 and NSP4 proteins enhanced the anti-NSP4 humoral responses in immunized mice. Microbial Pathogenesis 163, pages 105405.
Crossref
Mark R. Zweigart, Sylvia Becker-Dreps, Filemón Bucardo, Fredman González, Ralph S. Baric & Lisa C. Lindesmith. (2021) Serological Humoral Immunity Following Natural Infection of Children with High Burden Gastrointestinal Viruses. Viruses 13:10, pages 2033.
Crossref
Elena A. Varyushina, Georgy V. Alexandrov, Mikhail S. Zakharov, Anna S. Kiryanova, Olga E. Huttunen, Alina B. Rumyantseva, Ilya D. Mitrofanov, Irina V. Bendt, Anna E. Krylova, Anastasia B. Chistyakova, Natalya A. Artemova, Irina M. Shatillo, Elena G. Bogomolova, Olga A. Dobrovolskaya, Sergey A. Ischuk, Ilya V. Dukhovlinov & Andrey S. Simbirtsev. (2021) Study of immunogenicity and safety of a candidate rotavirus vaccine based on a recombinant hybrid protein. Medical academic journal 21:2, pages 87-98.
Crossref
Kirsi Tamminen, Suvi Heinimäki, Stina Gröhn & Vesna Blazevic. (2021) Fusion Protein of Rotavirus VP6 and SARS-CoV-2 Receptor Binding Domain Induces T Cell Responses. Vaccines 9:7, pages 733.
Crossref
Maha Masoudi, Ali Teimoori, Alijan Tabaraei, Majid Shahbazi, Marzieh Divbandi, Nazanin Lorestani, Ahad Yamchi & Hadi Razavi Nikoo. (2020) Advanced sequence optimization for the high efficient yield of human group A rotavirus VP6 recombinant protein in Escherichia coli and its use as immunogen . Journal of Medical Virology 93:6, pages 3549-3556.
Crossref
Stina Gröhn, Suvi Heinimäki, Kirsi Tamminen & Vesna Blazevic. (2020) Expression of influenza A virus-derived peptides on a rotavirus VP6-based delivery platform. Archives of Virology 166:1, pages 213-217.
Crossref
Alan Fix, Carl D. Kirkwood, Duncan Steele & Jorge Flores. (2020) Next-generation rotavirus vaccine developers meeting: Summary of a meeting sponsored by PATH and the bill & melinda gates foundation (19–20 June 2019, Geneva). Vaccine 38:52, pages 8247-8254.
Crossref
Sarah L. Caddy, Marina Vaysburd, Mark Wing, Stian Foss, Jan Terje Andersen, Kevin O‘Connell, Keith Mayes, Katie Higginson, Miren Iturriza-Gómara, Ulrich Desselberger & Leo C. James. (2020) Intracellular neutralisation of rotavirus by VP6-specific IgG. PLOS Pathogens 16:8, pages e1008732.
Crossref
Kirsi Tamminen, Suvi Heinimäki, Stina Gröhn & Vesna Blazevic. (2020) Internalization and antigen presentation by mouse dendritic cells of rotavirus VP6 preparations differing in nanostructure. Molecular Immunology 123, pages 26-31.
Crossref
Stanley A. Plotkin. (2020) Updates on immunologic correlates of vaccine-induced protection. Vaccine 38:9, pages 2250-2257.
Crossref
Suvi Heinimäki, Minna M. Hankaniemi, Amir-Babak Sioofy-Khojine, Olli H. Laitinen, Heikki Hyöty, Vesa P. Hytönen, Timo Vesikari & Vesna Blazevic. (2019) Combination of three virus-derived nanoparticles as a vaccine against enteric pathogens; enterovirus, norovirus and rotavirus. Vaccine 37:51, pages 7509-7518.
Crossref
Maria Malm, Timo Vesikari & Vesna Blazevic. (2019) Simultaneous Immunization with Multivalent Norovirus VLPs Induces Better Protective Immune Responses to Norovirus than Sequential Immunization. Viruses 11:11, pages 1018.
Crossref
Maria Malm, André Diessner, Kirsi Tamminen, Markus Liebscher, Timo Vesikari & Vesna Blazevic. (2019) Rotavirus VP6 as an Adjuvant for Bivalent Norovirus Vaccine Produced in Nicotiana benthamiana. Pharmaceutics 11:5, pages 229.
Crossref
Atefeh Afchangi, Somayeh Jalilvand, Nasir Mohajel, Sayed Mahdi Marashi & Zabihollah Shoja. (2019) Rotavirus VP6 as a potential vaccine candidate. Reviews in Medical Virology 29:2, pages e2027.
Crossref
Felix Fingas, Antje Rückner, Kristin Heenemann, Daniela Volke, Michael Sieg, Petra Bielefeldt, Thomas Grunwald, Thomas W. Vahlenkamp, Rayk Hassert & Ralf Hoffmann. (2018) Highly sensitive ELISA for the serological detection of murine rotavirus EDIM based on its major immunogen VP6. Journal of Virological Methods 262, pages 72-78.
Crossref
Kirsi Tamminen, Maria Malm, Timo Vesikari & Vesna Blazevic. (2018) Norovirus-specific mucosal antibodies correlate to systemic antibodies and block norovirus virus-like particles binding to histo-blood group antigens. Clinical Immunology 197, pages 110-117.
Crossref
Suvi Heinimäki, Maria Malm, Timo Vesikari & Vesna Blazevic. (2018) Intradermal and intranasal immunizations with oligomeric middle layer rotavirus VP6 induce Th1, Th2 and Th17 T cell subsets and CD4 + T lymphocytes with cytotoxic potential. Antiviral Research 157, pages 1-8.
Crossref
Mariano Carossino, Maria E. Barrandeguy, Yanqiu Li, Viviana Parreño, Jennifer Janes, Alan T. Loynachan & Udeni B.R. Balasuriya. (2018) Detection, molecular characterization and phylogenetic analysis of G3P[12] and G14P[12] equine rotavirus strains co-circulating in central Kentucky. Virus Research 255, pages 39-54.
Crossref
Atefeh AfchangiArash ArashkiaZahra ShahosseiniSomayeh JalilvandSayed Mahdi MarashiFarzin RoohvandNasir MohajelZabihollah Shoja. (2018) Immunization of Mice by Rotavirus NSP4-VP6 Fusion Protein Elicited Stronger Responses Compared to VP6 Alone. Viral Immunology 31:3, pages 233-241.
Crossref
Stanley A. Plotkin & Peter Gilbert. 2018. Plotkin's Vaccines. Plotkin's Vaccines 35 40.e4 .
Anita Meier, Mark Suter, Elisabeth Schraner, Bruno Humbel, Kurt Tobler, Mathias Ackermann & Andrea Laimbacher. (2017) Transfer of Anti-Rotavirus Antibodies during Pregnancy and in Milk Following Maternal Vaccination with a Herpes Simplex Virus Type-1 Amplicon Vector. International Journal of Molecular Sciences 18:2, pages 431.
Crossref
Suvi Lappalainen, Vesna Blazevic, Maria Malm & Timo Vesikari. (2017) Rotavirus vaccination and infection induce VP6-specific IgA responses. Journal of Medical Virology 89:2, pages 239-245.
Crossref
Arturo S. Gastañaduy & Rodolfo E. Bégué. 2017. Infectious Diseases. Infectious Diseases 1390 1398.e3 .
Gökçe Günaydın, Shengze Yu, Torbjörn Gräslund, Lennart Hammarström & Harold Marcotte. (2016) Fusion of the mouse IgG1 Fc domain to the VHH fragment (ARP1) enhances protection in a mouse model of rotavirus. Scientific Reports 6:1.
Crossref
Ana Carolina Bernardes Dulgheroff, George Allan Villarouco da Silva, Felipe Gomes Naveca, Adriana Gonçalves de Oliveira & André Luiz da Silva Domingues. (2016) Diversity of group A rotavirus genes detected in the Triângulo Mineiro region, Minas Gerais, Brazil. Brazilian Journal of Microbiology 47:3, pages 731-740.
Crossref
Kirsi TamminenMaria MalmTimo VesikariVesna Blazevic. (2016) Mucosal Antibodies Induced by Intranasal but Not Intramuscular Immunization Block Norovirus GII.4 Virus-Like Particle Receptor Binding. Viral Immunology 29:5, pages 315-319.
Crossref
Maria Malm, Kirsi Tamminen, Suvi Lappalainen, Timo Vesikari & Vesna Blazevic. (2016) Rotavirus Recombinant VP6 Nanotubes Act as an Immunomodulator and Delivery Vehicle for Norovirus Virus-Like Particles. Journal of Immunology Research 2016, pages 1-13.
Crossref
T. Vesikari. 2016. Viral Gastroenteritis. Viral Gastroenteritis 301 328 .
Filemón Bucardo & Johan Nordgren. (2015) Impact of vaccination on the molecular epidemiology and evolution of group A rotaviruses in Latin America and factors affecting vaccine efficacy. Infection, Genetics and Evolution 34, pages 106-113.
Crossref
Suvi Lappalainen, Ana Ruth Pastor, Maria Malm, Vanessa López-Guerrero, Fernando Esquivel-Guadarrama, Laura A. Palomares, Timo Vesikari & Vesna Blazevic. (2015) Protection against live rotavirus challenge in mice induced by parenteral and mucosal delivery of VP6 subunit rotavirus vaccine. Archives of Virology 160:8, pages 2075-2078.
Crossref
Jukka Markkula, Maria Hemming & Timo Vesikari. (2015) Detection of Vaccine-derived Rotavirus Strains in Nonimmunocompromised Children up to 3–6 Months After RotaTeq® Vaccination. Pediatric Infectious Disease Journal 34:3, pages 296-298.
Crossref

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.