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mAbs Volume 5, 2013 - Issue 1
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Generation and characterization of rendomab-B1, a monoclonal antibody displaying potent and specific antagonism of the human endothelin B receptor

Bertrand Allard CEA; iBiTecS; SPI; Laboratoire d’Ingénierie des Anticorps pour la Santé (LIAS); Gif sur Yvette, France
,
Anne WIJKHUISEN CEA; iBiTecS; SPI; Laboratoire d’Ingénierie des Anticorps pour la Santé (LIAS); Gif sur Yvette, France; Univ Paris Diderot; Sorbonne Paris Cité; EA 3515; Gif sur France
,
Aurélie Borrull CEA; iBiTecS; SPI; Laboratoire d’Ingénierie des Anticorps pour la Santé (LIAS); Gif sur Yvette, France
,
Frederique Deshayes Univ Paris Diderot; Sorbonne Paris Cité; IJM; Paris, France
,
Fabienne Priam CEA; iBiTecS; SPI; Laboratoire d’Ingénierie des Anticorps pour la Santé (LIAS); Gif sur Yvette, France; Univ Paris Diderot; Sorbonne Paris Cité; EA 3515; Gif sur France
,
Patricia Lamourette CEA; iBiTecS; SPI; Laboratoire d’Etudes et de Recherche en Immunoanalyse (LERI); Gif sur Yvette, France.
,
Frédéric Ducancel CEA; iBiTecS; SPI; Laboratoire d’Ingénierie des Anticorps pour la Santé (LIAS); Gif sur Yvette, France
,
Didier Boquet CEA; iBiTecS; SPI; Laboratoire d’Ingénierie des Anticorps pour la Santé (LIAS); Gif sur Yvette, France
&
Jean-Yves Couraud CEA; iBiTecS; SPI; Laboratoire d’Ingénierie des Anticorps pour la Santé (LIAS); Gif sur Yvette, France; Univ Paris Diderot; Sorbonne Paris Cité; EA 3515; Gif sur France
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Pages 56-69 | Received 07 Sep 2012, Accepted 28 Oct 2012, Published online: 05 Dec 2012

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Marie Hautiere, Irene Maffucci, Narciso Costa, Amaury Herbet, Sosthene Essono, Séverine Padiolleau-Lefevre & Didier Boquet. (2023) The functionality of a therapeutic antibody candidate restored by a single mutation from proline to threonine in the variable region. Human Vaccines & Immunotherapeutics 19:3.
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Aurélie Borrull, Bertrand Allard, Anne Wijkhuisen, Amaury Herbet, Patricia Lamourette, Wided Birouk, Denis Leiber, Zahra Tanfin, Frédéric Ducancel, Didier Boquet, Jean-Yves Couraud & Philippe Robin. (2016) Rendomab B4, a monoclonal antibody that discriminates the human endothelin B receptor of melanoma cells and inhibits their migration. mAbs 8:7, pages 1371-1385.
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Christine J Rossant, Danielle Carroll, Ling Huang, John Elvin, Frances Neal, Edward Walker, Joris J Benschop, Eldar E Kim, Simon T Barry & Tristan J Vaughan. (2014) Phage display and hybridoma generation of antibodies to human CXCR2 yields antibodies with distinct mechanisms and epitopes. mAbs 6:6, pages 1425-1438.
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Margaux Lejeune, Murat Cem Köse, Mégane Jassin, Marie-Jia Gou, Amaury Herbet, Elodie Duray, Gaël Cobraiville, Jacques Foguenne, Didier Boquet, André Gothot, Yves Beguin, Marianne Fillet & Jo Caers. (2023) Integrative Analysis of Proteomics and Transcriptomics Reveals Endothelin Receptor B as Novel Single Target and Identifies New Combinatorial Targets for Multiple Myeloma. HemaSphere 7:7, pages e901.
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Adriana Torres Crigna, Barbara Link, Marek Samec, Frank A. Giordano, Peter Kubatka & Olga Golubnitschaja. (2021) Endothelin-1 axes in the framework of predictive, preventive and personalised (3P) medicine. EPMA Journal 12:3, pages 265-305.
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Matthias BartonMasashi Yanagisawa. (2019) Endothelin: 30 Years From Discovery to Therapy. Hypertension 74:6, pages 1232-1265.
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Vidyanand Anaparti. (2018) Anti-GPCR Antibodies. Materials and Methods 8.
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Tam T.T.N. Nguyen, Ulrik H. Mistarz, Narciso Costa, Amaury Herbet, Didier Boquet, François Becher & Kasper D. Rand. (2018) Investigating the utility of minimized sample preparation and high-resolution mass spectrometry for quantification of monoclonal antibody drugs. Journal of Pharmaceutical and Biomedical Analysis 159, pages 384-392.
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Roger B. Dodd, Trevor Wilkinson & Darren J. Schofield. (2018) Therapeutic Monoclonal Antibodies to Complex Membrane Protein Targets: Antigen Generation and Antibody Discovery Strategies. BioDrugs 32:4, pages 339-355.
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A. P. DAVENPORT, R. E. KUC, C. SOUTHAN & J. J. MAGUIRE. (2018) New Drugs and Emerging Therapeutic Targets in the Endothelin Signaling Pathway and Prospects for Personalized Precision Medicine. Physiological Research, pages S37-S54.
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A. HERBET, N. COSTA, N. LEVENTOUX, A. MABONDZO, J.-Y. COURAUD, A. BORRULL, J.-P. HUGNOT & D. BOQUET. (2018) Antibodies Targeting Human Endothelin-1 Receptors Reveal Different Conformational States in Cancer Cells. Physiological Research, pages S257-S264.
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Isabella S. Kim, Silja Heilmann, Emily R. Kansler, Yan Zhang, Milena Zimmer, Kajan Ratnakumar, Robert L. Bowman, Theresa Simon-Vermot, Myles Fennell, Ralph Garippa, Liang Lu, William Lee, Travis Hollmann, Joao B. Xavier & Richard M. White. (2017) Microenvironment-derived factors driving metastatic plasticity in melanoma. Nature Communications 8:1.
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Nicolas Martin, Narciso Costa, Frank Wien, Françoise M. Winnik, Céline Ortega, Amaury Herbet, Didier Boquet & Christophe Tribet. (2017) Refolding of Aggregation-Prone ScFv Antibody Fragments Assisted by Hydrophobically Modified Poly(sodium acrylate) Derivatives. Macromolecular Bioscience 17:2, pages 1600213.
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John-David Aubert & Lucienne Juillerat-Jeanneret. (2016) Endothelin-Receptor Antagonists beyond Pulmonary Arterial Hypertension: Cancer and Fibrosis. Journal of Medicinal Chemistry 59:18, pages 8168-8188.
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Trevor C.I. Wilkinson. (2016) Discovery of functional monoclonal antibodies targeting G-protein-coupled receptors and ion channels. Biochemical Society Transactions 44:3, pages 831-837.
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Anthony P. Davenport, Kelly A. Hyndman, Neeraj Dhaun, Christopher Southan, Donald E. Kohan, Jennifer S. Pollock, David M. Pollock, David J. Webb & Janet J. Maguire. (2016) Endothelin. Pharmacological Reviews 68:2, pages 357-418.
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Nelia Cordeiro, Anne Wijkhuisen, Alexandra Savatier, Natacha Moulharat, Gilles Ferry & Michel Léonetti. (2016) Obtaining anti-type 1 melatonin receptor antibodies by immunization with melatonin receptor-expressing cells. Journal of Immunological Methods 428, pages 37-41.
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S. Richard, M. BoucherA. HerbetY. Lalatonne, S. MériauxD. BoquetL. Motte. (2015) Endothelin B receptors targeted by iron oxide nanoparticles functionalized with a specific antibody: toward immunoimaging of brain tumors. Journal of Materials Chemistry B 3:15, pages 2939-2942.
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J J Maguire & A P Davenport. (2014) Endothelin@25 – new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR R eview 12 . British Journal of Pharmacology 171:24, pages 5555-5572.
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