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mAbs Volume 6, 2014 - Issue 5
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Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist

Thilipan ThaventhiranMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
,
Naif AlhumeedMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
,
Han XA YeangMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK;Rheumatology Division; Washington University School of Medicine; Saint Louis, MOUSA
,
Swaminathan SethuMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK;School of Bio Sciences & Technology and Centre for Biomaterials Science & Technology; VIT University; Vellore, India
,
Jocelyn S DowneySt. Edmund's College; University of Cambridge; Cambridge, UK
,
Ahmad F AlghanemMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
,
Adedamola OlayanjuMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
,
Emma L SmithMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
,
Michael J CrossMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
,
Steven D WebbMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
,
Dominic P WilliamsMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
,
Adrian BristowNational Institute for Biological Standards and Control; Potters Bar; Hertfordshire, UK
,
Christina BallNational Institute for Biological Standards and Control; Potters Bar; Hertfordshire, UK
,
Richard StebbingsNational Institute for Biological Standards and Control; Potters Bar; Hertfordshire, UK
&
Jean G SathishMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UKCorrespondence[email protected]
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Pages 1290-1299 | Received 08 Jun 2014, Accepted 26 Jun 2014, Published online: 30 Oct 2014

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Tatyana Khramova, Liubov Beduleva, Alexandr Sidorov, Alexey Terentiev & Igor Menshikov. (2023) Regulatory Rheumatoid Factor is Specific to PD-1 and Uses PD-1 Pathway to Control CD4 T Lymphocytes. Immunological Investigations 52:7, pages 897-908.
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Francesca R. Mariotti, Stefania Petrini, Tiziano Ingegnere, Nicola Tumino, Francesca Besi, Francesca Scordamaglia, Enrico Munari, Silvia Pesce, Emanuela Marcenaro, Alessandro Moretta, Paola Vacca & Lorenzo Moretta. (2019) PD-1 in human NK cells: evidence of cytoplasmic mRNA and protein expression. OncoImmunology 8:3.
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Articles from other publishers (7)

Tatyana V. Khramova, Liubov V. Beduleva, Kseniya V. Fomina & Nadezhda N. Abisheva. (2023) Flow cytometry analysis of PD1 expression on rat blood CD3<sup>+</sup> lymphocytes stimulated by CD3 antibodies. Russian Journal of Immunology 26:3, pages 415-420.
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Yiran Liang, Ning Xue, Xiaoyan Wang, Xiaoqiang Ding & Yi Fang. (2019) Superagonistic CD28 protects against renal ischemia injury induced fibrosis through a regulatory T-cell expansion dependent mechanism. BMC Nephrology 20:1.
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Thilipan ThaventhiranWai WongAhmad F. AlghanemNaif AlhumeedMohammad A. AljasirSimeon RamseySwaminathan SethuHan Xian Aw YeangAmy E. ChadwickMichael CrossSteven D. WebbLaiche DjouhriChristina BallRichard StebbingsJean G. Sathish. (2019) CD28 Superagonistic Activation of T Cells Induces a Tumor Cell-Like Metabolic Program. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy 38:2, pages 60-69.
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Nicla Porciello, Martina Kunkl & Loretta Tuosto. (2018) CD28 between tolerance and autoimmunity: the side effects of animal models. F1000Research 7, pages 682.
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Shixue Dai, Hongxiang Gu, Qianyi Lin, Tiaosi Xing, Minhua Chen, Tao Zhong, Gang Wu, Yanling Feng, Hongbo Liu, Yong Gao, Hongjian Jian, Minhai Zhang, Hongmei Mo, Huanjie Zhu, Dongsheng Chen, Jun Xu, Ying Zou, Honggang Chi & Yuzhen Zhu. (2016) Disequilibrium in the CD8+CD28+/CD8+CD28− T Lymphocyte Balance Is Related to Prognosis in Rats with Trinitrobenzenesulfonic Acid-Induced Colitis. Digestive Diseases and Sciences 62:3, pages 639-651.
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Jonathan H. Esensten, Ynes A. Helou, Gaurav Chopra, Arthur Weiss & Jeffrey A. Bluestone. (2016) CD28 Costimulation: From Mechanism to Therapy. Immunity 44:5, pages 973-988.
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Thulasi Ramani, Carol S. Auletta, Daniel Weinstock, Barbara Mounho-Zamora, Patricia C. Ryan, Theodora W. Salcedo & Gregory Bannish. (2015) Cytokines. International Journal of Toxicology 34:4, pages 355-365.
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