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Failure to upregulate cell surface PD-1 is associated with dysregulated stimulation of T cells by TGN1412-like CD28 superagonist
Thilipan ThaventhiranMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
, Naif AlhumeedMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
, Han XA YeangMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK;Rheumatology Division; Washington University School of Medicine; Saint Louis, MOUSA
, Swaminathan SethuMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK;School of Bio Sciences & Technology and Centre for Biomaterials Science & Technology; VIT University; Vellore, India
, Jocelyn S DowneySt. Edmund's College; University of Cambridge; Cambridge, UK
, Ahmad F AlghanemMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
, Adedamola OlayanjuMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
, Emma L SmithMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
, Michael J CrossMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
, Steven D WebbMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
, Dominic P WilliamsMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UK
, Adrian BristowNational Institute for Biological Standards and Control; Potters Bar; Hertfordshire, UK
, Christina BallNational Institute for Biological Standards and Control; Potters Bar; Hertfordshire, UK
, Richard StebbingsNational Institute for Biological Standards and Control; Potters Bar; Hertfordshire, UK
& Jean G SathishMedical Research Council Centre for Drug Safety Science and Department of Molecular and Clinical Pharmacology; University of Liverpool; Liverpool, UKCorrespondence[email protected]
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Pages 1290-1299
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Received 08 Jun 2014, Accepted 26 Jun 2014, Published online: 30 Oct 2014
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