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mAbs Volume 4, 2012 - Issue 1
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Immunotoxins constructed with chimeric, short-lived anti-CD22 monoclonal antibodies induce less vascular leak without loss of cytotoxicity

Xiao-yun Liu The Cancer Immunobiology Center; University of Texas Southwestern Medical Center at Dallas; Dallas, TX USA; These authors contributed equally to this study
,
Laurentiu M. Pop The Cancer Immunobiology Center; University of Texas Southwestern Medical Center at Dallas; Dallas, TX USA; These authors contributed equally to this study
,
John Schindler The Cancer Immunobiology Center; University of Texas Southwestern Medical Center at Dallas; Dallas, TX USA
&
Ellen S. Vitetta The Cancer Immunobiology Center; University of Texas Southwestern Medical Center at Dallas; Dallas, TX USA; Departments of Immunology and Microbiology; University of Texas Southwestern Medical Center at Dallas; Dallas, TX USACorrespondence[email protected]
Pages 57-68 | Received 26 Aug 2011, Accepted 08 Oct 2011, Published online: 01 Jan 2012

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Serengulam V Govindan & David M Goldenberg. (2012) Designing immunoconjugates for cancer therapy. Expert Opinion on Biological Therapy 12:7, pages 873-890.
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Yanjie Peng, Zhengli Wu, Zheng Pang, Lin Zhang, Dandan Song, Fang Liu, Yanhong Li & Tongjun Lin. (2023) Manufacture and evaluation of a HER2-positive breast cancer immunotoxin 4D5Fv-PE25. Microbial Cell Factories 22:1.
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Xiao-Ping Li, Rajesh K. Harijan, Bin Cao, Jennifer N. Kahn, Michael Pierce, Anastasiia M. Tsymbal, Jacques Y. Roberge, David Augeri & Nilgun E. Tumer. (2021) Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design. Journal of Medicinal Chemistry 64:20, pages 15334-15348.
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M. Knödler & J.F. Buyel. (2021) Plant-made immunotoxin building blocks: A roadmap for producing therapeutic antibody-toxin fusions. Biotechnology Advances 47, pages 107683.
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Xiao-Ping Li, Rajesh K. Harijan, Jennifer N. Kahn, Vern L. Schramm & Nilgun E. Tumer. (2020) Small Molecule Inhibitors Targeting the Interaction of Ricin Toxin A Subunit with Ribosomes. ACS Infectious Diseases 6:7, pages 1894-1905.
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Carlos Leónidas Leiva, M. Julián Gallardo, Natalia Casanova, Horacio Terzolo & Pablo Chacana. (2020) IgY-technology (egg yolk antibodies) in human medicine: A review of patents and clinical trials. International Immunopharmacology 81, pages 106269.
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Michael Pierce, Diana Vengsarkar, John E. McLaughlin, Jennifer N. Kahn & Nilgun E. Tumer. (2019) Ribosome depurination by ricin leads to inhibition of endoplasmic reticulum stress–induced HAC1 mRNA splicing on the ribosome. Journal of Biological Chemistry 294:47, pages 17848-17862.
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Natalia Sowa-Rogozińska, Hanna Sominka, Jowita Nowakowska-Gołacka, Kirsten Sandvig & Monika Słomińska-Wojewódzka. (2019) Intracellular Transport and Cytotoxicity of the Protein Toxin Ricin. Toxins 11:6, pages 350.
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Jijie Gu, Andrew McCluskey & Tariq Ghayur. 2017. Protein Therapeutics. Protein Therapeutics 229 270 .
D. Hendriks, G. Choi, M. de Bruyn, V.R. Wiersma & E. Bremer. 2017. 289 383 .
Christiane Chen-Santel. 2017. Childhood Acute Lymphoblastic Leukemia. Childhood Acute Lymphoblastic Leukemia 201 237 .
Sergio Rosales-MendozaSergio Rosales-Mendoza. 2016. Algae-Based Biopharmaceuticals. Algae-Based Biopharmaceuticals 77 93 .
Jing Ai & Anjali Advani. (2015) Current status of antibody therapy in ALL. British Journal of Haematology 168:4, pages 471-480.
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Laura K. Hmiel, Kurt A. Brorson & Michael T. BoyneIIII. (2014) Post-translational structural modifications of immunoglobulin G and their effect on biological activity. Analytical and Bioanalytical Chemistry 407:1, pages 79-94.
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Alan S. Wayne, David J. FitzGerald, Robert J. Kreitman & Ira Pastan. (2014) Immunotoxins for leukemia. Blood 123:16, pages 2470-2477.
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Anjali S. Advani. (2013) New immune strategies for the treatment of acute lymphoblastic leukemia: antibodies and chimeric antigen receptors. Hematology 2013:1, pages 131-137.
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Miller Tran, Ryan E. Henry, David Siefker, Christina Van, Greg Newkirk, Julie Kim, Jack Bui & Stephen P. Mayfield. (2013) Production of anti-cancer immunotoxins in algae: Ribosome inactivating proteins as fusion partners. Biotechnology and Bioengineering 110:11, pages 2826-2835.
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Letizia Polito, Massimo Bortolotti, Daniele Mercatelli, Maria Battelli & Andrea Bolognesi. (2013) Saporin-S6: A Useful Tool in Cancer Therapy. Toxins 5:10, pages 1698-1722.
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Monika Słomińska-Wojewódzka & Kirsten Sandvig. (2013) Ricin and Ricin-Containing Immunotoxins: Insights into Intracellular Transport and Mechanism of action in Vitro. Antibodies 2:4, pages 236-269.
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Sivasubramanian Baskar & Natarajan Muthusamy. (2012) Antibody-based Therapeutics for the Treatment of Human B cell Malignancies. Current Allergy and Asthma Reports 13:1, pages 33-43.
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