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IL-17A is a central regulator of lung tumor growth

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Pages 783-785 | Published online: 24 Aug 2012

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Qi Tan, Limin Duan, Qi Huang, Wenjuan Chen, Zimo Yang, Jiangbin Chen & Yang Jin. (2021) Interleukin -1β Promotes Lung Adenocarcinoma Growth and Invasion Through Promoting Glycolysis via p38 Pathway. Journal of Inflammation Research 14, pages 6491-6509.
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Yuhong Liu, Claire E. O'Leary, Liang-Chuan S. Wang, Tricia R. Bhatti, Ning Dai, Veena Kapoor, Peihui Liu, Junjie Mei, Lei Guo, Paula M. Oliver, Steven M. Albelda & G. Scott Worthen. (2016) CD11b+Ly6G+ cells inhibit tumor growth by suppressing IL-17 production at early stages of tumorigenesis. OncoImmunology 5:1.
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Meiying Song, Jie Liang, Luoyang Wang, Wei Li, Suli Jiang, Shuo Xu, Lei Tang, Qiaochu Du, Guixian Liu, Haining Meng, Dongchang Zhai, Shangheng Shi, Yanyan Yang, Li Zhang & Bei Zhang. (2023) IL-17A functions and the therapeutic use of IL-17A and IL-17RA targeted antibodies for cancer treatment. International Immunopharmacology 123, pages 110757.
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Mai Tanaka & Dietmar W. Siemann. (2021) Therapeutic Targeting of the Gas6/Axl Signaling Pathway in Cancer. International Journal of Molecular Sciences 22:18, pages 9953.
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Ronald Anderson, Ada Gabriela Blidner & Bernardo Leon Rapoport. (2021) Frontiers in Pharmacology: Review Manuscript Targeting of the Neutrophil as an Adjunctive Strategy in Non-Small Cell Lung Cancer. Frontiers in Pharmacology 12.
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Paula X. Losada, José S. Cortés, Carlos F. Narváez & Giovani Lastra. (2021) Papel de la interleuquina-17 en procesos inflamatorios y patologías pulmonares. Revista Médicas UIS 34:1.
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Yi-Fang Yang, Yu-Chan Chang, Yi-Hua Jan, Chih-Jen Yang, Ming-Shyan Huang & Michael Hsiao. (2020) Squalene synthase promotes the invasion of lung cancer cells via the osteopontin/ERK pathway. Oncogenesis 9:8.
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Xie Chao, Liu Yi, Li Lan Lan, Han Yun Wei & Dong Wei. (2020) Long-term PM2.5 exposure increases the risk of non-small cell lung cancer (NSCLC) progression by enhancing interleukin-17a (IL-17a)-regulated proliferation and metastasis. Aging 12:12, pages 11579-11602.
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Monika Migdalska-Sęk, Katarzyna Góralska, Sławomir Jabłoński, Jacek Kordiak, Ewa Nawrot, Justyna M. Kiszałkiewicz, Dorota Pastuszak-Lewandoska, Kamila Baran, Michał Stuss & Ewa Brzeziańska-Lasota. (2019) Evaluation of the relationship between the IL-17A gene expression level and regulatory miRNA-9 in relation to tumor progression in patients with non-small cell lung cancer: a pilot study. Molecular Biology Reports 47:1, pages 583-592.
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Sadiya Bi Shaikh, Ashwini Prabhu & Yashodhar Prabhakar Bhandary. (2019) Interleukin-17A: A Potential Therapeutic Target in Chronic Lung Diseases. Endocrine, Metabolic & Immune Disorders - Drug Targets 19:7, pages 921-928.
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Lourdes Barrera, Edgar Montes-Servín, Juan-Manuel Hernandez-Martinez, Mario Orozco-Morales, Elizabeth Montes-Servín, David Michel-Tello, Renato Augusto Morales-Flores, Diana Flores-Estrada & Oscar Arrieta. (2018) Levels of peripheral blood polymorphonuclear myeloid-derived suppressor cells and selected cytokines are potentially prognostic of disease progression for patients with non-small cell lung cancer. Cancer Immunology, Immunotherapy 67:9, pages 1393-1406.
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Pedro O. Flores-Villanueva, Malathesha Ganachari, Heinner Guio, Jaime A. Mejia & Julio Granados. (2018) An Isolated TCR αβ Restricted by HLA-A*02:01/CT37 Peptide Redirecting CD8+ T Cells To Kill and Secrete IFN-γ in Response to Lung Adenocarcinoma Cell Lines. The Journal of Immunology 200:8, pages 2965-2977.
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Qi Huang, limin Duan, Xin Qian, Jinshuo Fan, Zhilei Lv, Xiuxiu Zhang, Jieli Han, Feng Wu, Mengfei Guo, Guorong Hu, Jiao Du, Caiyun Chen & Yang Jin. (2016) IL-17 Promotes Angiogenic Factors IL-6, IL-8, and Vegf Production via Stat1 in Lung Adenocarcinoma. Scientific Reports 6:1.
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Sarah Reppert, Elisabeth Zinser, Corinna Holzinger, Lena Sandrock, Sonja Koch & Susetta Finotto. (2015) NFATc1 deficiency in T cells protects mice from experimental autoimmune encephalomyelitis. European Journal of Immunology 45:5, pages 1426-1440.
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Bob Yang, Heechan Kang, Anthony Fung, Hailin Zhao, Tianlong Wang & Daqing Ma. (2014) The Role of Interleukin 17 in Tumour Proliferation, Angiogenesis, and Metastasis. Mediators of Inflammation 2014, pages 1-12.
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Markus F. Neurath & Susetta Finotto. (2012) The emerging role of T cell cytokines in non-small cell lung cancer. Cytokine & Growth Factor Reviews 23:6, pages 315-322.
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Lisanne Heim, Mircea T. Chiriac, Katerina Kachler, Sarah Mitsch, Zuqin Yang, Julia Koelle, Rakshin Kharwadkar, Carol-Immanuel Geppert, Patrick Tausche, Katja Hohenberger, Anna Graser, Juliane Friedrich, Ralf J. Rieker, Denis I. Trufa, Horia Sirbu, Markus F. Neurath, Mark H. Kaplan & Susetta Finotto. (2021) IL-9 Producing Tumor-Infiltrating Lymphocytes (Til) and Treg Subsets Drive Immune Escape of Tumor Cells in Non-Small Cell Lung Cancer. SSRN Electronic Journal.
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