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OncoImmunology Volume 2, 2013 - Issue 12

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A novel recombinant immunotoxin-based therapy targeting wild-type and mutant EGFR improves survival in murine models of glioblastoma

Vidyalakshmi Chandramohan Preston Robert Tisch Brain Tumor Center at Duke; Duke University Medical Center; Durham, NC USA; Department of Pathology; Duke University Medical Center; Durham, NC USACorrespondence[email protected]

Darell D Bigner Preston Robert Tisch Brain Tumor Center at Duke; Duke University Medical Center; Durham, NC USA; Department of Pathology; Duke University Medical Center; Durham, NC USA

Article: e26852 | Received 14 Oct 2013, Accepted 17 Oct 2013, Published online: 22 Oct 2013

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https://doi.org/10.4161/onci.26852

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Cuimin Deng, Jiani Xiong, Xiaofan Gu, Xiaoying Chen, Shuifa Wu, Zhe Wang, Duanduan Wang, Jinjin Tu & Jieming Xie. (2017) Novel recombinant immunotoxin of EGFR specific nanobody fused with cucurmosin, construction and antitumor efficiency in vitro . Oncotarget 8:24, pages 38568-38580.
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Shaowei Zhu, Yuanyi Liu, Paul C. Wang, Xinbin Gu & Liang Shan. (2017) Recombinant Immunotoxin Therapy of Glioblastoma: Smart Design, Key Findings, and Specific Challenges. BioMed Research International 2017, pages 1-18.
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Judith Niesen, Christoph Stein, Hannes Brehm, Grit Hehmann-Titt, Rolf Fendel, Georg Melmer, Rainer Fischer & Stefan Barth. (2015) Novel EGFR-specific immunotoxins based on panitumumab and cetuximab show in vitro and ex vivo activity against different tumor entities. Journal of Cancer Research and Clinical Oncology 141:12, pages 2079-2095.
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Judith Niesen, Hannes Brehm, Christoph Stein, Nina Berges, Alessa Pardo, Rainer Fischer, Andre ten Haaf, Stefan Gattenlöhner, Mehmet K. Tur & Stefan Barth. (2014) In vitro effects and ex vivo binding of an EGFR-specific immunotoxin on rhabdomyosarcoma cells. Journal of Cancer Research and Clinical Oncology 141:6, pages 1049-1061.
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A novel recombinant immunotoxin-based therapy targeting wild-type and mutant EGFR improves survival in murine models of glioblastoma

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A novel recombinant immunotoxin-based therapy targeting wild-type and mutant EGFR improves survival in murine models of glioblastoma

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