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Organogenesis Forum

Four danger response programs determine glomerular and tubulointerstitial kidney pathology

Clotting, inflammation, epithelial and mesenchymal healing

Pages 29-40 | Published online: 01 Apr 2012

Keep up to date with the latest research on this topic with citation updates for this article.

Read on this site (2)

Lena Succar, Julia Lai-Kwon, David J Nikolic-Paterson & Gopala K Rangan. (2014) Induction monotherapy with sirolimus has selected beneficial effects on glomerular and tubulointersititial injury in nephrotoxic serum nephritis. International Journal of Nephrology and Renovascular Disease 7, pages 303-313.
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Hai-Feng Ni, Jun-Feng Chen, Ming-Hui Zhang, Ming-Ming Pan, Jian-Dong Zhang, Hong Liu, Ri-Ning Tang, Kun-Ling Ma & Bi-Cheng Liu. (2013) FTY720 attenuates tubulointerstitial inflammation and fibrosis in subtotally nephrectomized rats. Renal Failure 35:7, pages 996-1004.
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Articles from other publishers (21)

Jing Chen, Yuwei Liu, Shang Xia, Xujun Ye & Ling Chen. (2022) Annexin A2 (ANXA2) regulates the transcription and alternative splicing of inflammatory genes in renal tubular epithelial cells. BMC Genomics 23:1.
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Jonatan Barrera‐Chimal, Frédéric Jaisser & Hans‐Joachim Anders. (2021) The mineralocorticoid receptor in chronic kidney disease. British Journal of Pharmacology 179:13, pages 3152-3164.
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Samiksha Wasnik, Xiaolei Tang, Hongzheng Bi, Amir Abdipour, Edmundo E. Carreon, Brian Sutjiadi, Justin Lyu, Jintao Zhang, Sean Wilson & David J. Baylink. (2020) IGF-1 Deficiency Rescue and Intracellular Calcium Blockade Improves Survival and Corresponding Mechanisms in a Mouse Model of Acute Kidney Injury. International Journal of Molecular Sciences 21:11, pages 4095.
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Chiara Poluzzi, Madalina-Viviana Nastase, Jinyang Zeng-Brouwers, Heiko Roedig, Louise Tzung-Harn Hsieh, Jonas B. Michaelis, Eva Miriam Buhl, Flavia Rezende, Yosif Manavski, André Bleich, Peter Boor, Ralf P. Brandes, Josef Pfeilschifter, Ernst H.K. Stelzer, Christian Münch, Ivan Dikic, Christian Brandts, Renato V. Iozzo, Malgorzata Wygrecka & Liliana Schaefer. (2019) Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury. Kidney International 95:3, pages 540-562.
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David A. Ferenbach, Eoin D. O’Sullivan & Joseph V. Bonventre. 2018. Core Concepts in Acute Kidney Injury. Core Concepts in Acute Kidney Injury 69 91 .
Daigo Nakazawa, Santhosh V. Kumar, Julian Marschner, Jyaysi Desai, Alexander Holderied, Lukas Rath, Franziska Kraft, Yutian Lei, Yuichiro Fukasawa, Gilbert W. Moeckel, Maria Lucia Angelotti, Helen Liapis & Hans-Joachim Anders. (2017) Histones and Neutrophil Extracellular Traps Enhance Tubular Necrosis and Remote Organ Injury in Ischemic AKI. Journal of the American Society of Nephrology 28:6, pages 1753-1768.
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Mehdi Salehipour, Ahmad Monabbati, Mohammad Reza Ensafdaran, Ali Adib & Amir Hossein Babaei. (2017) The effect of zinc on healing of renal damage in rats. Journal of Nephropathology 6:3, pages 157-162.
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Shrikant R. Mulay, Santhosh V. Kumar, Maciej Lech, Jyaysi Desai & Hans-Joachim Anders. (2016) How Kidney Cell Death Induces Renal Necroinflammation. Seminars in Nephrology 36:3, pages 162-173.
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Onkar P. Kulkarni, Julia Lichtnekert, Hans-Joachim Anders & Shrikant R. Mulay. (2016) The Immune System in Tissue Environments Regaining Homeostasis after Injury: Is ?Inflammation? Always Inflammation?. Mediators of Inflammation 2016, pages 1-9.
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Shrikant R. Mulay, Alexander Holderied, Santhosh V. Kumar & Hans-Joachim Anders. (2016) Targeting Inflammation in So-Called Acute Kidney Injury. Seminars in Nephrology 36:1, pages 17-30.
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Hans-Joachim Anders & Liliana Schaefer. (2014) Beyond Tissue Injury—Damage-Associated Molecular Patterns, Toll-Like Receptors, and Inflammasomes Also Drive Regeneration and Fibrosis. Journal of the American Society of Nephrology 25:7, pages 1387-1400.
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Hans-Joachim Anders & Agnes B. Fogo. (2014) Immunopathology of lupus nephritis. Seminars in Immunopathology 36:4, pages 443-459.
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Onkar P. Kulkarni, Ingo Hartter, Shrikant R. Mulay, Jan Hagemann, Murthy N. Darisipudi, Santhosh Kumar VR, Simone Romoli, Dana Thomasova, Mi Ryu, Sebastian Kobold & Hans-Joachim Anders. (2014) Toll-Like Receptor 4–Induced IL-22 Accelerates Kidney Regeneration. Journal of the American Society of Nephrology 25:5, pages 978-989.
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Yu-Sheng Lin, Gary Ginsberg, Jou-Wei Lin & Babasaheb Sonawane. (2014) Mercury exposure and omega-3 fatty acid intake in relation to renal function in the US population. International Journal of Hygiene and Environmental Health 217:4-5, pages 465-472.
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S. R. Mulay, A. Evan & H.-J. Anders. (2013) Molecular mechanisms of crystal-related kidney inflammation and injury. Implications for cholesterol embolism, crystalline nephropathies and kidney stone disease. Nephrology Dialysis Transplantation 29:3, pages 507-514.
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Hans-Joachim Anders. (2013) Innate versus adaptive immunity in kidney immunopathology. BMC Nephrology 14:1.
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Roman Günthner, Vankayala Kumar, Georg Lorenz, Hans-Joachim Anders & Maciej Lech. (2013) Pattern-Recognition Receptor Signaling Regulator mRNA Expression in Humans and Mice, and in Transient Inflammation or Progressive Fibrosis. International Journal of Molecular Sciences 14:9, pages 18124-18147.
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Jan H. Hagemann, Dana Thomasova, Shrikant R. Mulay & Hans-Joachim Anders. (2013) Nrf2 signalling promotes ex vivo tubular epithelial cell survival and regeneration via murine double minute (MDM)-2. Nephrology Dialysis Transplantation 28:8, pages 2028-2037.
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Maciej Lech & Hans-Joachim Anders. (2013) Macrophages and fibrosis: How resident and infiltrating mononuclear phagocytes orchestrate all phases of tissue injury and repair. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1832:7, pages 989-997.
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Shrikant R Mulay, Dana Thomasova, Mi Ryu, Onkar P Kulkarni, Adriana Migliorini, Hauke Bruns, Regina Gröbmayr, Elena Lazzeri, Laura Lasagni, Helen Liapis, Paola Romagnani & Hans-Joachim Anders. (2013) Podocyte loss involves MDM2-driven mitotic catastrophe. The Journal of Pathology 230:3, pages 322-335.
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Maciej Lech, Regina Gr?bmayr, Marc Weidenbusch & Hans-Joachim Anders. (2012) Tissues Use Resident Dendritic Cells and Macrophages to Maintain Homeostasis and to Regain Homeostasis upon Tissue Injury: The Immunoregulatory Role of Changing Tissue Environments. Mediators of Inflammation 2012, pages 1-15.
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