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Research Paper

Anti-LRP/LR Antibody W3 Hampers Peripheral PrPSc Propagation in Scrapie Infected Mice

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Pages 207-212 | Received 13 Sep 2007, Accepted 07 Nov 2007, Published online: 28 Nov 2007

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Katarina Jovanovic, Carryn J Chetty, Thandokuhle Khumalo, Bianca Da Costa Dias, Eloise Ferreira, Sibusiso T Malindisa, Robert Caveney, Boitelo T Letsolo & Stefan FT Weiss. (2015) Novel patented therapeutic approaches targeting the 37/67 kDa laminin receptor for treatment of cancer and Alzheimer’s disease. Expert Opinion on Therapeutic Patents 25:5, pages 567-582.
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Huiying Gu, Richard C Dodel, Martin R Farlow & Yansheng Du. (2014) Advances in the development of antibody-based immunotherapy against prion disease. Antibody Technology Journal 4, pages 45-55.
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Aadilah Omar, Katarina Jovanovic, Bianca Da Costa Dias, Danielle Gonsalves, Kiashanee Moodley, Robert Caveney, Vusi Mbazima & Stefan FT Weiss. (2011) Patented biological approaches for the therapeutic modulation of the 37 kDa/67 kDa laminin receptor. Expert Opinion on Therapeutic Patents 21:1, pages 35-53.
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Suehiro Sakaguchi, Daisuke Ishibashi & Haruo Matsuda. (2009) Antibody-based immunotherapeutic attempts in experimental animal models of prion diseases. Expert Opinion on Therapeutic Patents 19:7, pages 907-917.
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Articles from other publishers (16)

Saima Zafar, Aneeqa Noor & Inga Zerr. 2019. Psychopharmacology of Neurologic Disease. Psychopharmacology of Neurologic Disease 47 58 .
Daniela Sarnataro, Anna Pepe, Gennaro Altamura, Imma De Simone, Ada Pesapane, Lucio Nitsch, Nunzia Montuori, Antonio Lavecchia & Chiara Zurzolo. (2016) The 37/67kDa laminin receptor (LR) inhibitor, NSC47924, affects 37/67kDa LR cell surface localization and interaction with the cellular prion protein. Scientific Reports 6:1.
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Kathrin Guitart, Gabriele Loers, Friedrich Buck, Ute Bork, Melitta Schachner & Ralf Kleene. (2016) Improvement of neuronal cell survival by astrocyte-derived exosomes under hypoxic and ischemic conditions depends on prion protein. Glia, pages n/a-n/a.
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James A. Mastrianni. 2015. Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease. Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease 229 254 .
Huinuan Wang, Lifeng Yang, Mohammed Kouadir, Rongrong Tan, Wenyu Wu, Huarong Zou, Jin Wang, Sher Hayat Khan, Dongfeng Li, Xiangmei Zhou, Xiaomin Yin, Yunsheng Wang & Deming Zhao. (2013) Expression and Distribution of Laminin Receptor Precursor/Laminin Receptor in Rabbit Tissues. Journal of Molecular Neuroscience 51:2, pages 591-601.
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Yvonne Roettger, Yansheng Du, Michael Bacher, Inga Zerr, Richard Dodel & Jan-Philipp Bach. (2012) Immunotherapy in prion disease. Nature Reviews Neurology 9:2, pages 98-105.
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Aadilah Omar, Uwe Reusch, Stefan Knackmuss, Melvyn Little & Stefan F.T. Weiss. (2012) Anti-LRP/LR-Specific Antibody IgG1-iS18 Significantly Reduces Adhesion and Invasion of Metastatic Lung, Cervix, Colon and Prostate Cancer Cells. Journal of Molecular Biology 419:1-2, pages 102-109.
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Saci Iken, Véronique Bachy, Pauline Gourdain, Annick Lim, Sylvie Grégoire, Thomas Chaigneau, Pierre Aucouturier & Claude Carnaud. (2011) Th2-polarised PrP-specific Transgenic T-cells Confer Partial Protection against Murine Scrapie. PLoS Pathogens 7:9, pages e1002216.
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Jyuri Kono, Ryoko Toyoshima, Tomoko Iseki, Yukita Sato, Atushi Umematu, Misuzu Okano, Akiko Tashiro, Yasuhisa Ano, Tetsutaro Sata, Takashi Yokoyama, Takashi Onodera & Masayoshi Yukawa. (2011) Uptake dynamics of scrapie agent in the intestinal villous epithelium of suckling and weanling Syrian hamsters. Microbiology and Immunology 55:9, pages 661-665.
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Alice Van den Broeke, Mario Van Poucke, Ane Marcos-Carcavilla, Karine Hugot, Hélène Hayes, Maud Bertaud, Alex Van Zeveren & Luc J Peelman. (2010) Characterization of the ovine ribosomal protein SA gene and its pseudogenes. BMC Genomics 11:1.
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Dominika Kolodziejczak, Bianca Da Costa Dias, Chantal Zuber, Katarina Jovanovic, Aadilah Omar, Julia Beck, Karen Vana, Vusi Mbazima, Juergen Richt, Bertram Brenig & Stefan F.T. Weiss. (2010) Prion Interaction with the 37-kDa/67-kDa Laminin Receptor on Enterocytes as a Cellular Model for Intestinal Uptake of Prions. Journal of Molecular Biology 402:2, pages 293-300.
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Heike Pflanz, Karen Vana, Gerda Mitteregger, Ingrid Renner-Müller, Claudia Pace, Helmut Küchenhoff, Hans A. Kretzschmar, Eckhard Wolf & Stefan Weiss. (2009) Scrapie-Infected Transgenic Mice Expressing a Laminin Receptor Decoy Mutant Reveal a Prolonged Incubation Time Associated with Low Levels of PrPres. Journal of Molecular Biology 388:4, pages 721-729.
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H. Pflanz, K. Vana, G. Mitteregger, C. Pace, D. Messow, C. Sedlaczek, D. Nikles, H. A. Kretzschmar & S. F. T. Weiss. (2009) Microinjection of lentiviral vectors expressing small interfering RNAs directed against laminin receptor precursor mRNA prolongs the pre-clinical phase in scrapie-infected mice. Journal of General Virology 90:1, pages 269-274.
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Chantal Zuber, Gerda Mitteregger, Natascha Schuhmann, Clémence Rey, Stefan Knackmuss, Wolfgang Rupprecht, Uwe Reusch, Claudia Pace, Melvyn Little, Hans A. Kretzschmar, Michael Hallek, Hildegard Büning & Stefan Weiss. (2008) Delivery of single-chain antibodies (scFvs) directed against the 37/67 kDa laminin receptor into mice via recombinant adeno-associated viral vectors for prion disease gene therapy. Journal of General Virology 89:8, pages 2055-2061.
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Chantal Zuber, Stefan Knackmuss, Georgeta Zemora, Uwe Reusch, Ekaterina Vlasova, Daniela Diehl, Vera Mick, Karin Hoffmann, Daphne Nikles, Thomas Fröhlich, Georg J. Arnold, Bertram Brenig, Eckhard Wolf, Harald Lahm, Melvyn Little & Stefan Weiss. (2008) Invasion of Tumorigenic HT1080 Cells Is Impeded by Blocking or Downregulating the 37-kDa/67-kDa Laminin Receptor. Journal of Molecular Biology 378:3, pages 530-539.
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Daphne Nikles, Karen Vana, Sabine Gauczynski, Heike Knetsch, Heike Ludewigs & Stefan Weiss. (2008) Subcellular localization of prion proteins and the 37 kDa/67 kDa laminin receptor fused to fluorescent proteins. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1782:5, pages 335-340.
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