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Review

A Structural Overview of the Vertebrate Prion Proteins

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Pages 185-197 | Received 03 Nov 2007, Accepted 08 Nov 2007, Published online: 04 Dec 2007

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Juliana N. Angelli, Yulli M. Passos, Julyana M. A. Brito, Jerson L. Silva, Yraima Cordeiro & Tuane C. R. G. Vieira. (2021) Rabbit PrP Is Partially Resistant to in vitro Aggregation Induced by Different Biological Cofactors. Frontiers in Neuroscience 15.
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Carlo Mustazza, Marco Sbriccoli, Paola Minosi & Carla Raggi. (2020) Small Molecules with Anti-Prion Activity. Current Medicinal Chemistry 27:33, pages 5446-5479.
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Alba Marín-Moreno, Juan Carlos Espinosa & Juan María Torres. 2020. Prions and Neurodegenerative Diseases. Prions and Neurodegenerative Diseases 147 177 .
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Nicholas J. Haley, Kahla Merrett, Amy Buros Stein, Dennis Simpson, Andrew Carlson, Gordon Mitchell, Antanas Staskevicius, Tracy Nichols, Aaron D. Lehmkuhl & Bruce V. Thomsen. (2019) Estimating relative CWD susceptibility and disease progression in farmed white-tailed deer with rare PRNP alleles. PLOS ONE 14:12, pages e0224342.
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Teferedegn EY, Tesfaye D & Un C. (2019) Valuing the investigation of Prion diseases in Ethiopia. International Journal of Agricultural Science and Food Technology, pages 001-005.
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Francesca Collu, Enrico Spiga, Nesrine Chakroun, Human Rezaei & Franca Fraternali. (2018) Probing the early stages of prion protein (PrP) aggregation with atomistic molecular dynamics simulations. Chemical Communications 54:57, pages 8007-8010.
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Nataraj S. Pagadala, Trent C. Bjorndahl, Michael Joyce, David S. Wishart, Khajamohiddin Syed & Abdolamir Landi. (2017) The compound (3-{5-[(2,5-dimethoxyphenyl)amino]-1,3,4-thiadiazolidin-2-yl}-5,8-methoxy-2H-chromen-2-one) inhibits the prion protein conversion from PrPC to PrPSc with lower IC50 in ScN2a cells. Bioorganic & Medicinal Chemistry 25:20, pages 5875-5888.
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Andrew R. Castle & Andrew C. Gill. (2017) Physiological Functions of the Cellular Prion Protein. Frontiers in Molecular Biosciences 4.
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Ankit Srivastava, Sakshi Sharma, Sandhya Sadanandan, Sakshi Gupta, Jasdeep Singh, Sarika Gupta, V. Haridas & Bishwajit Kundu. (2017) Modulation of prion polymerization and toxicity by rationally designed peptidomimetics. Biochemical Journal 474:1, pages 123-147.
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Pu Chun Ke, Marc-Antonie Sani, Feng Ding, Aleksandr Kakinen, Ibrahim Javed, Frances Separovic, Thomas P. Davis & Raffaele Mezzenga. (2017) Implications of peptide assemblies in amyloid diseases. Chemical Society Reviews 46:21, pages 6492-6531.
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Victoria Lewis. 2017. Prions. Prions 119 132 .
Tuğçe Birkan, Mesut Şahin, Zübeyde Öztel & Erdal Balcan. (2016) Do prion protein gene polymorphisms induce apoptosis in non-mammals?. Journal of Biosciences 41:1, pages 97-107.
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Victoria Lewis, Vanessa A. Johanssen, Peter J. Crouch, Genevieve M. Klug, Nigel M. Hooper & Steven J. Collins. (2015) Prion protein “gamma-cleavage”: characterizing a novel endoproteolytic processing event. Cellular and Molecular Life Sciences 73:3, pages 667-683.
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Nicholas J. HaleyEdward A. Hoover. (2015) Chronic Wasting Disease of Cervids: Current Knowledge and Future Perspectives. Annual Review of Animal Biosciences 3:1, pages 305-325.
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Timothy D. Kurt, Lin Jiang, Cyrus Bett, David Eisenberg & Christina J. Sigurdson. (2014) A Proposed Mechanism for the Promotion of Prion Conversion Involving a Strictly Conserved Tyrosine Residue in the β2-α2 Loop of PrPC. Journal of Biological Chemistry 289:15, pages 10660-10667.
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Vladimir Espinosa Angarica, Salvador Ventura & Javier Sancho. (2013) Discovering putative prion sequences in complete proteomes using probabilistic representations of Q/N-rich domains. BMC Genomics 14:1.
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Arpana Dutta, Shugui Chen & Witold K. Surewicz. (2013) The effect of β2‐α2 loop mutation on amyloidogenic properties of the prion protein. FEBS Letters 587:18, pages 2918-2923.
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Magdalena Rowinska‐Zyrek, Daniela Valensin, Marek Luczkowski & Henryk Kozlowski. 2013. Mechanisms and Metal Involvement in Neurodegenerative Diseases. Mechanisms and Metal Involvement in Neurodegenerative Diseases 118 162 .
Yvonne Roettger, Inga Zerr, Richard Dodel & Jan-Philipp Bach. (2013) Prion Peptide Uptake in Microglial Cells – The Effect of Naturally Occurring Autoantibodies against Prion Protein. PLoS ONE 8:6, pages e67743.
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Bilkiss B. Issack, Mark Berjanskii, David S. Wishart & Maria Stepanova. (2012) Exploring the essential collective dynamics of interacting proteins: Application to prion protein dimers. Proteins: Structure, Function, and Bioinformatics, pages n/a-n/a.
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Jerson L. Silva, Tuane C.R.G. Vieira, Mariana P.B. Gomes, Luciana P. Rangel, Sandra M.N. Scapin & Yraima Cordeiro. (2011) Experimental approaches to the interaction of the prion protein with nucleic acids and glycosaminoglycans: Modulators of the pathogenic conversion. Methods 53:3, pages 306-317.
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Fernando Bergasa-Caceres & Herschel A. Rabitz. (2010) Low Entropic Barrier to the Hydrophobic Collapse of the Prion Protein: Effects of Intermediate States and Conformational Flexibility. The Journal of Physical Chemistry A 114:26, pages 6978-6982.
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Miquel Adrover, Kris Pauwels, Stephanie Prigent, Cesira de Chiara, Zhou Xu, Céline Chapuis, Annalisa Pastore & Human Rezaei. (2010) Prion Fibrillization Is Mediated by a Native Structural Element That Comprises Helices H2 and H3. Journal of Biological Chemistry 285:27, pages 21004-21012.
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