Advanced search
Publication Cover
Prion Volume 7, 2013 - Issue 2
Submit an article Journal homepage
1,135
Views
22
CrossRef citations to date
0
Altmetric
Extra View

Cis phosphorylated tau as the earliest detectable pathogenic conformation in Alzheimer disease, offering novel diagnostic and therapeutic strategies

Kazuhiro Nakamura Department of Medicine; Beth Israel Deaconess Medical Center; Harvard Medical School; Boston, MA USACorrespondence[email protected] [email protected] [email protected]
,
Xiao Zhen Zhou Department of Medicine; Beth Israel Deaconess Medical Center; Harvard Medical School; Boston, MA USACorrespondence[email protected] [email protected] [email protected]
&
Kun Ping Lu Department of Medicine; Beth Israel Deaconess Medical Center; Harvard Medical School; Boston, MA USACorrespondence[email protected] [email protected] [email protected]
Pages 117-120 | Received 14 Sep 2012, Accepted 11 Nov 2012, Published online: 15 Nov 2012

Citations (22)

Keep up to date with the latest research on this topic with citation updates for this article.

Subscribe to citation updates

Read on this site (1)

Koorosh Shahpasand, Alireza Sepehri Shamloo, Seyed Massood Nabavi, Kun Ping Lu & Xiao Zhen Zhou. (2018) “Tau immunotherapy: Hopes and hindrances”. Human Vaccines & Immunotherapeutics 14:2, pages 277-284.
Read now

Articles from other publishers (21)

Nancy R. Stallings, Melissa A. O’Neal, Jie Hu, Zhong-Jian Shen & James S. Malter. (2023) Long-term normalization of calcineurin activity in model mice rescues Pin1 and attenuates Alzheimer’s phenotypes without blocking peripheral T cell IL-2 response. Alzheimer's Research & Therapy 15:1.
Crossref
Forough Chakari-Khiavi, Arezoo Mirzaie, Balal Khalilzadeh, Hadi Yousefi, Rozita Abolhasan, Amin Kamrani, Ramin Pourakbari, Koorosh Shahpasand, Mehdi Yousefi & Mohammad-Reza Rashidi. (2023) Application of Pt@ZIF-8 nanocomposite-based electrochemical biosensor for sensitive diagnosis of tau protein in Alzheimer’s disease patients. Scientific Reports 13:1.
Crossref
Shaqayeq Roqanian, Shahin Ahmadian, Seyed Masood Nabavi, Hossein Pakdaman, Mahshid Shafiezadeh, Ghazaleh Goudarzi & Koorosh Shahpasand. (2022) Tau nuclear translocation is a leading step in tau pathology process through P53 stabilization and nucleolar dispersion. Journal of Neuroscience Research 100:4, pages 1084-1104.
Crossref
Yun Wei, Meixia Liu & Dongxin Wang. (2021) The propagation mechanisms of extracellular tau in Alzheimer’s disease. Journal of Neurology 269:3, pages 1164-1181.
Crossref
Elnaz Nakhjiri, Manuchehr S. Vafaee, Seyed Mohammad Massod Hojjati, Parviz Shahabi & Koorosh Shahpasand. (2020) Tau Pathology Triggered by Spinal Cord Injury Can Play a Critical Role in the Neurotrauma Development. Molecular Neurobiology 57:11, pages 4845-4855.
Crossref
Fatemeh Hadi, Hassan Akrami, Koorosh Shahpasand & Mohammad R. Fattahi. (2020) Wnt signalling pathway and tau phosphorylation: A comprehensive study on known connections. Cell Biochemistry and Function 38:6, pages 686-694.
Crossref
Yetunde Makinwa, Phillip R. Musich & Yue Zou. (2020) Phosphorylation-Dependent Pin1 Isomerization of ATR: Its Role in Regulating ATR’s Anti-apoptotic Function at Mitochondria, and the Implications in Cancer. Frontiers in Cell and Developmental Biology 8.
Crossref
Alice Bittar, Nemil Bhatt & Rakez Kayed. (2020) Advances and considerations in AD tau-targeted immunotherapy. Neurobiology of Disease 134, pages 104707.
Crossref
Jorge Baquero, Sophia Varriano, Martha Ordonez, Pawel Kuczaj, Michael R. Murphy, Gamage Aruggoda, Devon Lundine, Viktoriya Morozova, Ali Elhadi Makki, Alejandra del C. Alonso & Frida E. Kleiman. (2019) Nuclear Tau, p53 and Pin1 Regulate PARN-Mediated Deadenylation and Gene Expression. Frontiers in Molecular Neuroscience 12.
Crossref
Cheril Tapia-Rojas, Fabian Cabezas-Opazo, Carol A. Deaton, Erick H. Vergara, Gail V.W. Johnson & Rodrigo A. Quintanilla. (2019) It’s all about tau. Progress in Neurobiology 175, pages 54-76.
Crossref
I A Clark & B Vissel. (2018) Therapeutic implications of how TNF links apolipoprotein E, phosphorylated tau, α-synuclein, amyloid-β and insulin resistance in neurodegenerative diseases. British Journal of Pharmacology 175:20, pages 3859-3875.
Crossref
Alexander J. MoszczynskiWendy StrongKathy XuAnn McKeeArthur BrownMichael J. Strong. (2018) Pathologic Thr 175 tau phosphorylation in CTE and CTE with ALS . Neurology 90:5.
Crossref
Joseph O. Ojo, Benoit Mouzon, Moustafa Algamal, Paige Leary, Cillian Lynch, Laila Abdullah, James Evans, Michael Mullan, Corbin Bachmeier, William Stewart & Fiona Crawford. (2016) Chronic Repetitive Mild Traumatic Brain Injury Results in Reduced Cerebral Blood Flow, Axonal Injury, Gliosis, and Increased T-Tau and Tau Oligomers. Journal of Neuropathology & Experimental Neurology 75:7, pages 636-655.
Crossref
James PanIan D. ConnollySean Dangelmajer, James Kintzing, Allen L. HoGerald Grant. (2016) Sports-related brain injuries: connecting pathology to diagnosis. Neurosurgical Focus 40:4, pages E14.
Crossref
Shahzad S. Khan & George S. Bloom. (2016) Tau: The Center of a Signaling Nexus in Alzheimer's Disease. Frontiers in Neuroscience 10.
Crossref
William MeehanIIIIIIRebekah MannixRoss ZafonteAlvaro Pascual-Leone. (2015) Chronic traumatic encephalopathy and athletes. Neurology 85:17, pages 1504-1511.
Crossref
Jan Torleif Pedersen & Einar M. Sigurdsson. (2015) Tau immunotherapy for Alzheimer's disease. Trends in Molecular Medicine 21:6, pages 394-402.
Crossref
Laura J. Blair, Jeremy D. Baker, Jonathan J. Sabbagh & Chad A. Dickey. (2015) The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease. Journal of Neurochemistry 133:1, pages 1-13.
Crossref
Jing-Zhang Wang & Yong Zhang. (2015) Configuration-specific immunotherapy targeting cis pThr231-Pro232 tau for Alzheimer disease. Journal of the Neurological Sciences 348:1-2, pages 253-255.
Crossref
Jonathan D. Moore & Andrew Potter. (2013) Pin1 inhibitors: Pitfalls, progress and cellular pharmacology. Bioorganic & Medicinal Chemistry Letters 23:15, pages 4283-4291.
Crossref
Kazuhiro Nakamura. (2013) Posttranslational Regulation of Microtubule-Related Molecules as a Potential Therapeutic Target for Neurodegeneration. The Kitakanto Medical Journal 63:3, pages 273-274.
Crossref

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.