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Commentary & View

Therapy for prion diseases: Insights from the use of RNA interference

Pages 121-128 | Received 31 Jul 2009, Accepted 16 Jun 2009, Published online: 01 Jul 2009

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Arianna Colini Baldeschi, Silvia Vanni, Marco Zattoni & Giuseppe Legname. (2020) Novel regulators of PrPC expression as potential therapeutic targets in prion diseases. Expert Opinion on Therapeutic Targets 24:8, pages 759-776.
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Xiaochen Zhou, Hao Bi, Justin Wong, Miyuki Shimoji, Yifan Wang, Jue Yuan, Xiangzhu Xiao, Gong-Xian Wang & Wen-Quan Zou. (2011) Alkylating Antitumor Drug Mechlorethamine Conceals A Structured PrP Domain and Inhibits in Vitro Prion Amplification. Journal of Toxicology and Environmental Health, Part A 74:22-24, pages 1493-1503.
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Sang-Gyun Kang, Yu-Mi Roh, Agnes Lau, David Westaway, Debbie McKenzie, Judd M. Aiken, Yong-Sun Kim & Han Sang Yoo. (2011) Establishment and characterization of Prnp knockdown neuroblastoma cells using dual microRNA-mediated RNA interference. Prion 5:2, pages 93-102.
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Giuseppe Legname. 2023. Encyclopedia of Cell Biology. Encyclopedia of Cell Biology 450 462 .
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Brian S. Appleby, Shashirekha Shetty & Mohamed Elkasaby. (2022) Genetic aspects of human prion diseases. Frontiers in Neurology 13.
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Su Woong Yoo, Gyungseok Oh, Jin Chul Ahn & Euiheon Chung. (2021) Non-Oncologic Applications of Nanomedicine-Based Phototherapy. Biomedicines 9:2, pages 113.
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Bhavesh D. Kevadiya, Brendan M. Ottemann, Midhun Ben Thomas, Insiya Mukadam, Saumya Nigam, JoEllyn McMillan, Santhi Gorantla, Tatiana K. Bronich, Benson Edagwa & Howard E. Gendelman. (2019) Neurotheranostics as personalized medicines. Advanced Drug Delivery Reviews 148, pages 252-289.
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Nataiya Susol, I. Petruch, Bogdan Cech, Dmytro Ostapiv & Vasulii Vlizlo. (2019) Гематологічні та біохімічні показники крові лабораторних щурів за введення новосинтезованих полімерних носіїв олігодезоксинуклеотидів. Lesya Ukrainka Eastern European National University Scientific Bulletin. Series: Biological Sciences:12(337), pages 224-229.
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Sang-Gyun Kang, Chiye Kim, Judd Aiken, Han Sang Yoo & Debbie McKenzie. (2017) Dual MicroRNA to Cellular Prion Protein Inhibits Propagation of Pathogenic Prion Protein in Cultured Cells. Molecular Neurobiology 55:3, pages 2384-2396.
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N. Yu. Susol, Yu. V. Martyn, N. V. Kuzmina & V. V. Vlizlo. (2016) EFFECT OF NANOCARRIERS WITH ANTISENSE OLIGONUCLEOTIDES ON HISTOLOGICAL STRUCTURE OF ORGANS SYNTHESIZING PRION-PROTEIN. The Animal Biology 18:3, pages 91-96.
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Alvin S. Das & Wen-Quan Zou. (2016) Prions: Beyond a Single Protein. Clinical Microbiology Reviews 29:3, pages 633-658.
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Sylvain Lehmann, Aroa Relano-Gines, Sarah Resina, Elsa Brillaud, Danielle Casanova, Charles Vincent, Claire Hamela, Sophie Poupeau, Mathieu Laffont, Audrey Gabelle, Constance Delaby, Maxime Belondrade, Jacques-Damien Arnaud, Maria-Teresa Alvarez, Jean-Claude Maurel, Patrick Maurel & Carole Crozet. (2014) Systemic Delivery of siRNA Down Regulates Brain Prion Protein and Ameliorates Neuropathology in Prion Disorder. PLoS ONE 9:2, pages e88797.
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Markus Geissen, Fabienne Leidel, Martin Eiden, Thomas Hirschberger, Christine Fast, Uwe Bertsch, Paul Tavan, Armin Giese, Hans Kretzschmar, Hermann M. Schatzl & Martin H. Groschup. (2011) From High-Throughput Cell Culture Screening to Mouse Model: Identification of New Inhibitor Classes against Prion Disease. ChemMedChem 6:10, pages 1928-1937.
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Maria Laura Bolognesi, Hoang Ngoc Ai Tran, Matteo Staderini, Alessandra Monaco, Alberto López-Cobeñas, Salvatore Bongarzone, Xevi Biarnés, Pilar López-Alvarado, Nieves Cabezas, Maria Caramelli, Paolo Carloni, J. Carlos Menéndez & Giuseppe Legname. (2010) Discovery of a Class of Diketopiperazines as Antiprion Compounds. ChemMedChem 5:8, pages 1324-1334.
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Julie A. MorenoGiovanna R. Mallucci. (2010) Dysfunction and recovery of synapses in prion disease: implications for neurodegeneration. Biochemical Society Transactions 38:2, pages 482-487.
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