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Nutrition and Cancer Volume 73, 2021 - Issue 10
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Review

RENISUS Plants and Their Potential Antitumor Effects in Clinical Trials and Registered Patents

Diorge Jônatas Marmitta Laboratório de Cultura de Células, Programa de Pós-graduação em Biotecnologia, Universidade do Vale do Taquari (Univates), Lajeado, BrazilCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-5454-9099View further author information
ORCID Icon,
Shanna Bitencourta Laboratório de Cultura de Células, Programa de Pós-graduação em Biotecnologia, Universidade do Vale do Taquari (Univates), Lajeado, BrazilORCID Iconhttps://orcid.org/0000-0002-5854-1550View further author information
ORCID Icon,
Gustavo Rodrigo da Silvab Centro de Ciências Biológicas e da Saúde, Universidade do Vale do Taquari (Univates), Lajeado, BrazilORCID Iconhttps://orcid.org/0000-0003-2669-4365View further author information
ORCID Icon,
Claudete Rempelc Programa de Pós-graduação em Ambiente e Desenvolvimento/Programa de Pós-graduação em Sistemas Ambientais Sustentáveis, Universidade do Vale do Taquari (Univates), Lajeado, BrazilORCID Iconhttps://orcid.org/0000-0001-8573-0237View further author information
ORCID Icon &
Márcia Inês Goetterta Laboratório de Cultura de Células, Programa de Pós-graduação em Biotecnologia, Universidade do Vale do Taquari (Univates), Lajeado, BrazilORCID Iconhttps://orcid.org/0000-0002-3648-5033View further author information
ORCID Icon
Pages 1821-1848 | Received 27 Dec 2019, Accepted 09 Aug 2020, Published online: 24 Aug 2020
 
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Abstract

Cancer is a significant cause of morbidity and mortality. Scientific advances, coupled with potential flaws in current treatments, are driving research into the discovery of new bioactive molecules. This systematic review focused on scientific studies with clinical trials and patents registered on the National Relation of Medicinal Plants of Interest to the Unified Health System (RENISUS) plants (or derivative compounds) with antitumor potential. Studies with 19 different forms of cancer were found, the prostate being the organ with the highest research incidence and the species Glycine max, Curcuma longa, and Zingiber officinale, beside the phytochemicals curcumin and soy isoflavone were the most tested in clinical trials/patents.

Disclosure statement

The authors report no conflict of interest.

Additional information

Funding

This work was supported by Univates, Fundação de Auxílio à Pesquisa do Estado do Rio Grande do Sul (FAPERGS). This study was financed in part by the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brasil (CAPES) Finance Code 001.

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