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Pediatric Hematology and Oncology Volume 37, 2020 - Issue 6
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Reports

Foveal photoreceptors loss and then recovery after treatment in a chronic myelogenous leukemia patient

Ning-Yi HsiaDepartment of Ophthalmology, China Medical University Hospital, Taichung, Taiwan; ;Department of Optometry, Asia University, Taichung, Taiwan; ;School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan; ORCID Iconhttp://orcid.org/0000-0002-9398-1316
ORCID Icon,
Chun-Ju LinDepartment of Ophthalmology, China Medical University Hospital, Taichung, Taiwan; ;Department of Optometry, Asia University, Taichung, Taiwan; ;School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan; Correspondence[email protected]
,
Hui-Ju LinDepartment of Ophthalmology, China Medical University Hospital, Taichung, Taiwan;
&
Kang-Hsi WuDepartment of Hematology, China Medical University Hospital, Taichung, Taiwan
Pages 545-548 | Received 28 Jul 2019, Accepted 21 Apr 2020, Published online: 04 May 2020
 
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Abstract

We report a 10-year-old boy with chronic myelogenous leukemia (CML)-related retinopathy of the eyes. Foveal photoreceptors loss was noted in the right eye, but it was restored with a continued ellipsoid zone after systemic 6-week imatinib mesylate and hydroxyurea treatment. Spectral-domain optical coherence tomography images of the foveal photoreceptors change in the right eye were taken. His best-corrected visual acuity of the right eye recovered from 20/100 to 20/20. Prompt treatment of the underlying CML could result in improvement or resolution of the ocular findings, and even foveal photoreceptors loss might be reversible with good visual acuity recovery.

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