Evaluating Auditory Pathway by Electrical Auditory Middle Latency Response and Postoperative Hearing Rehabilitation

ABSTRACT

Objective: To establish an effective detection method to evaluate auditory pathway in patients by electrical evoked middle latency response (EMLR) before artificial cochlear implantation, and to analyze the relationship between postoperative hearing rehabilitation and auditory cortex functions. Methods: Twenty-three patients with artificial cochlear implant were recruited. EMLR was measured after adjusting the depth of anesthesia. The electrical auditory brainstem response (EABR) mode with monopolar stimulation and two-phase alternating current square waves was selected. The parameters of EMLR waveforms were recorded by the EABR measurement system. Nerve response telemetry (NRT) was examined by measuring threshold level (T value) and comfortable level (C value) 1 month after power-on, and hearing and speech development was followed up 12 months later.Results: The detection rate of EMLR was 95.65%. The waveforms of EMLR were comparable to those of auditory middle latency response (AMLR), showing decreased latency and interval but similar amplitude. The induction rate of NRT was 69.23%, which was much lower than that of EMLR. The EMLR thresholds were significantly correlated to the T and C values, and were comparable to the T values numerically. The Spearman's r value between EMLR waveforms and CAP scores after using the cochlear implant for 12 months was 0.673 (P < 0.01). Conclusion: An effective detection method to measure EMLR before artificial cochlear implant was established. The thresholds of EMLR were lower than those of NRT. The method can be useful for objective evaluation of auditory cortex functions and postoperative hearing rehabilitation.

Keywords::

• electrical stimulation
• artificial cochlear implantation
• auditory assessment
• auditory middle latency response
• category of auditory perception

DECLARATION OF INTEREST

All the authors declare that they have no conflict of interest.

ETHICS APPROVAL AND CONSENT TO PARTICIPATE

Informed consent forms were signed and obtained from all participants. The study was approved by the Ethics Committee of the Peking union medical college hospital, P. R. China.

Additional information

Funding

This study was partially supported by the Beijing Municipal Science & Technology Commission, PR China (No. Z171100001017218).