Human microbiota in aging and infection: A review

ABSTRACT

In most developed countries, ageing of the population started more than a century ago and it seems to be emerged in a wide range of developing countries as well.

Moreover, research into ageing has moved forward in extremely rapidly rhythms nowadays, and the scientific area is of great interest, as implications for nearly all sectors of society, including work, social, economic features, in addition to nutrition and health issues which are involved.

The fragile elder population is affected and experienced more frequently infections than the younger population. Infections in elderly patients are of major medical importance because of hormonal changes, increased production of pro-inflammatory cytokines and chemokines, abnormalities of the telomeres which could cause a dysfunction of the immune system called immunosenescence and malnutrition.

KEYWORDS:

• Ageing
• CYP cytochromes
• infection
• microbiota
• nutrition
• probiotics

Conflict of interest

The authors whose names are listed immediately below report that they don't have any conflict of interest or involvement in an organization or entity with a financial or non-financial interest in the subject matter or materials discussed in this manuscript.

Moreover, this work was not financially supported by any grant or other body as it is a review article.