ABSTRACT
The antioxidant potential (% RSA and EC50) of solvent extracts of leaves and roots of Lobelia nicotianifolia Roth. was assessed using five in vitro assays. The EC50 values of methanolic extract were comparable to that of ascorbic acid for nitric oxide (30.67 µg mL−1) and hydrogen peroxide (81.01 µg mL−1) radical assays. The % RSA and EC50 correlated with the total phenolic content and total flavonoid content. The characterization by liquid chromatography-high-resolution mass spectrometry showed the presence of five flavonoids, six phenolics, three carotenoids, one anthraquinone, coumarin, hydroxyquinone, and isoflavonoid. Embelin, gallic acid, and quercetin were quantified by high-performance liquid chromatography.
Acknowledgments
The authors are grateful to Mr. Vijay Mohan Crishna (Director, NGCPR) for providing research funds under the in-house funding scheme and Dr. Mayur D. Nandikar (Head and Scientist) for providing the necessary research facilities at NGCPR.
Disclosure Statement
No potential conflict of interest was reported by the authors.