Cell Models to Evaluate Antioxidant Properties of the Phlorotannins in Brown Seaweed: A Review

ABSTRACT

Phlorotannins are a kind of polyphenolics extracted from brown seaweed, which have a series of biological activities. It is worth mentioning that the antioxidant activity of phlorotannins has been widely used in the fields of medicines, cosmetics and food. And there are various chemical and biological methods for evaluating the antioxidant activity of phlorotannins. Due to the lack of accuracy and authenticity of chemiluminescence, cell models gradually become the mainstream method based on more realistic biological environment. Based on the above reasons, this paper summarized the research progress of phlorotannins in cell models, potential mechanism of antioxidant activity and factors affecting antioxidant activity of phlorotannins in recent years. The aim is to provide valuable experience for the future development of marine resources, the research and application of antioxidant phlorotannins and the treatment of human oxidative stress diseases.

KEYWORDS:

• Phlorotannins
• antioxidant activity
• cell models
• potential mechanism

Acknowledgments

This work was financially supported by The National Natural Science Foundation of China (grant number: 31972143) and The National Key Research and Development Program of China (grant number: 2019YFD0902001) and Young Top Talents Project of Liaoning Revitalization Talents Program (grant number: XLYC1807166) and Dalian Science and Technology Foundation for Distinguished Young Scholars (grant number: 2018RL07).

Additional information

Funding

This work was supported by the National Natural Science Foundation of China [31972143]; Dalian Science and Technology Foundation for Distinguished Young Scholars [2018RL07]; The National Key Research and Development Program of China [2019YFD0902001]; Young Top Talents Project of Liaoning Revitalization Talents Program [XLYC1807166].