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Analytical Letters Volume 48, 2015 - Issue 12
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Vibrational Spectroscopy

Microchip-Based Surface Enhanced Raman Spectroscopy for the Determination of Sodium Thiocyanate in Milk

Zheng-Yong ZhangSchool of Management Science & Engineering, Nanjing University of Finance & Economics, Nanjing, Jiangsu, China;Jiangsu Province Institute of Quality & Safety Engineering, Nanjing, Jiangsu, China
,
Jun LiuSchool of Management Science & Engineering, Nanjing University of Finance & Economics, Nanjing, Jiangsu, China;Jiangsu Province Institute of Quality & Safety Engineering, Nanjing, Jiangsu, China
&
Hai-Yan WangSchool of Management Science & Engineering, Nanjing University of Finance & Economics, Nanjing, Jiangsu, China;Jiangsu Province Institute of Quality & Safety Engineering, Nanjing, Jiangsu, ChinaCorrespondence[email protected]
Pages 1930-1940 | Received 06 Oct 2014, Accepted 29 Dec 2014, Published online: 26 May 2015
 
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Abstract

A simple integrated agarose microchip-based substrate is reported for surface enhanced Raman spectroscopy. The substrate was evaluated for the determination of sodium thiocyanate in milk. The limit of detection was 5 × 10−7 grams per milliliter. The microarray design allowed the synchronous processing of many samples. The reported procedure is green and practical for on-site determination of sodium thiocyanate in milk with potential for additional applications.

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