Abstract
A simple synthesis of eudesmin (1) is described. The key fragments were diol 13, dicarbethoxyethane 4, and diketo diester 5, which were prepared via reductive catalytic hydrogenation and oxidative intermolecular coupling of carbanions. This method is useful to generate the core skeleton of an endo–endo furofuran ring.
Acknowledgments
This work was supported by Korea Science and Engineering Foundation (KOSEF) (Grant No. RO5‐2004‐000‐10742–0).