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Original Articles

Treatment of opioid use disorder with ibogaine: detoxification and drug use outcomes

, PhD & , MD
Pages 24-36 | Received 11 Sep 2016, Accepted 16 Apr 2017, Published online: 25 May 2017

Figures & data

Table 1. Demographic and drug use characteristics and prior treatment history of the study sample.

Table 2. ASIC scores at pretreatment baseline and 1, 3, 6, 9, and 12 months, and opioid free days: Paired t-tests were used to compare ASIC scores at 1, 3, 6, 9, and 12 months posttreatment to their baseline pretreatment values (N = 30; significance level of p-values indicated by †). Noninferiority tests were used to compare ASIC scores at 3, 6, 9, and 12 months posttreatment to their 1-month posttreatment values (n = 20; significance level of p-values indicated by *). The means and standard deviations are unadjusted and computed on the subjects (n) available at the respective time point. The p-values are adjusted for missing follow-up data by performing the respective statistical tests with missing values set equal to their baseline pretreatment value as described in Methods. Opioid-free days in the previous 30 days are shown in the lower part of the Table.

Figure 1. Individual trajectories of the ASIC Drug Use score in all subjects available at one or more follow-up time points subsequent to treatment (n = 26).

Figure 1. Individual trajectories of the ASIC Drug Use score in all subjects available at one or more follow-up time points subsequent to treatment (n = 26).