Corneal Collagen Cross-Linking Complications

ABSTRACT

Corneal cross-linking was approved by United States Food and Drug Administration for the treatment of progressive keratoconus in April 2016. As this approach becomes more widely used for the treatment of keratoconus and post-laser in situ keratomileusis (LASIK) ectasia, the medical community is becoming more familiar with potential complications associated with this procedure. This article aims to review the reported complications of collagen cross-linking for the treatment of keratoconus and post-LASIK ectasia.

Keywords:

• Ectasia
• epi-off
• epi-on
• keratoconus (KCN)
• post-LASIK ectasia
• transepithelial cross-linking (TE CXL)

DECLARATION OF INTEREST

Kathryn M. Hatch is a consultant for Avedro Inc. There are no other conflicts of interest. The authors alone are responsible for the content and writing of the article.