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Studies in humans

Gluten-free diet intervention reduces thiamine intake in two weeks, increases glycaemic response and decreases body weight in four weeks, with no long term nutritional deficiencies

, , , & ORCID Icon
Pages 367-377 | Received 26 Jun 2021, Accepted 12 Sep 2021, Published online: 28 Sep 2021

Figures & data

Table 1. A list of foods given to the participants to choose gluten-free products in study two. (Source: Coeliac UK; www.coeliac.org.uk).

Table 2. Characteristics of participants who followed Gluten-containing diet (n = 11) and Gluten-free diet (n = 11) in study one.

Table 3. Participant characteristics (n = 11) before and after the Gluten-free diet intervention in study two.

Figure 1. Change in (a) blood glucose concentration (mean ± SEM) and (b) plasma insulin concentration (mean ± SEM) in the GFD and GCD group during OGTT. GFD: Gluten free diet; GCD: Gluten-containing diet; OGTT; oral glucose tolerance test.

Figure 1. Change in (a) blood glucose concentration (mean ± SEM) and (b) plasma insulin concentration (mean ± SEM) in the GFD and GCD group during OGTT. GFD: Gluten free diet; GCD: Gluten-containing diet; OGTT; oral glucose tolerance test.

Figure 2. Change in (a) blood glucose concentration (mean ± SEM) and (b) plasma insulin concentration (mean ± SEM) during OGTT before and after the 4-week GFD intervention. Asterisk (*) denotes a significant difference (p<.05). OGTT: oral glucose tolerance test; GFD: Gluten free diet.

Figure 2. Change in (a) blood glucose concentration (mean ± SEM) and (b) plasma insulin concentration (mean ± SEM) during OGTT before and after the 4-week GFD intervention. Asterisk (*) denotes a significant difference (p<.05). OGTT: oral glucose tolerance test; GFD: Gluten free diet.

Table 4. The average daily energy and nutrient intake for participants in the gluten-containing diet group and gluten-free diet group (study one).

Table 5. Nutritional intake before and after the 4-week Gluten-free diet intervention (study two).

Data availability statement

Data available on request from the authors. The data that support the findings of this study are available from the corresponding author [PST], upon reasonable request.