https://orcid.org/0000-0002-9720-7491
Figures & data
Figure 1. Alterations of overarching processes that sustain health can be considered as a key feature of the onset of non-communicable, multifactorial diseases (Van Ommen Citation2009). Core health processes, that is, carbohydrate metabolism, lipid metabolism, inflammation, oxidative stress and microbiota status, are proposed as measurable elements of these overarching processes. The status of core health processes can be assessed by omics profiling, and further characterized by integrating genetic markers that are informative of complementary aspects. Information provided by assessment of core health processes status can be further used to deliver nutritional recommendations based in dietary patterns with sufficient scientific basis in order to modulate behavior and dietary habits affecting overarching processes.
Figure 2. The approach proposed in this review was implemented in a tangible personalized nutrition system in the project PREVENTOMICS. (A) The system combined metabolomic, proteomic and genetic data together with results of data analysis for scoring the five core health processes. (B) The information on core health processes scores was further combined with behavioral information within a decision support system. (C) The decision support system was accessed by different softwares that could retrieve specific information about the user to elaborate personalized recommendations.
