Quantification of coumarin and related phenolics in cinnamon samples from south India using UHPLC-ESI-QqQ_LIT-MS/MS method

Figures & data

Figure 1. Structures of standard analytes (1–5).

Table 1. Cinnamon samples, source, sample code and herbarium number.

Sl. No.	Source	Code	Herbarium No.
1	Commercial source	M-1	Market sample
2	Commercial source	M-2	Market sample
3	Commercial source	M-3	Market sample
4	Commercial source	M-4	Market sample
5	Commercial source	M-5	Market sample
6	Cinnamon plantation, Kannur	M-6	81424
7	Cinnamon plantation, Kannur	M-7	81425
8	IISR plantation, Calicut	M-8	81426
9	IISR variety, Calicut	M-9	81427
10	JNTBGRI, Thiruvananthapuram	M-10	81420

Figure 2. TICs of (a). Standard analytes positive and negative combined mode (1-coumarin, 2-scopoletin, 3-E-o-coumaric acid, 4-cinnamic acid and 5-cinnamaldehyde) (b). Cinnamon market sample M-1 and (c). Cinnamon authentic sample M-6.

Table 2. Content (mg/kg dry weight) of analytes in C. verum bark samples (mean ± SD, n = 3).

Sample code	Scopoletin	E-o-coumaric acid	Coumarin	Cinnamic acid	Cinnamaldehyde
M-1	3.3 ± 0.7	18.9 ± 1.3	3462 ± 156	285 ± 11	18580 ± 451
M-2	6.0 ± 1.1	6.8 ± 1.8	819 ± 43	183 ± 21	5792 ± 203
M-3	5.3 ± 1.2	40.3 ± 2.3	914 ± 32	188 ± 17	8440 ± 225
M-4	3.1 ± 0.9	13.0 ± 1.2	2159 ± 85	282 ± 9	10558 ± 441
M-5	2.9 ± 0.5	7.3 ± 1.1	19.6 ± 2.1	34.2 ± 2.8	2828 ± 138
M-6	3.2 ± 1.3	5.8 ± 0.6	12.3 ± 0.9	17.6 ± 1.2	141 ± 18
M-7	6.8 ± 1.5	15.1 ± 1.9	67.8 ± 3.5	57.8 ± 3.1	403 ± 12
M-8	5.3 ± 0.9	17.7 ± 2.4	24.5 ± 1.2	27.5 ± 1.7	106 ± 9
M-9	3.4 ± 0.8	17.9 ± 2.9	42.5 ± 1.1	72.5 ± 3.4	2330 ± 66
M-10	4.3 ± 0.5	5.7 ± 1.5	143 ± 2.3	51.5 ± 2.2	1388 ± 42

Figure 3. Coumarin content (mg/kg) in cinnamon samples (M-1 to M-10).