The inhibition profile of sesamol against α-glycosidase and acetylcholinesterase enzymes

Figures & data

Figure 1. Chemical structure of sesamol

Table 1. IC₅₀ and K_i values, inhibition types of the sesamol on acetylcholinesterase (AChE) and α-glycosidase

Enzymes	IC50(nM)	r^2	Ki (nM)	Inhibition Type
AChE	86.63	0.9871	46.68 ± 7.51	Non-competitive
α-Glycosidase	99.00 nM	0.9567	75.33 ± 31.69	Non-competitive

Figure 2. Determination of IC₅₀ (a) and K_i (b) values of the Sesamol on acetylcholinesterase (AChE) enzyme

Figure 3. Determination of IC₅₀ (a) and K_i (b) values of the Sesamol on α-glycosidase enzyme

Figure 4. α-Glycosidase enzyme releases from small intestine and hydrolyzes the oligosaccharides and polysaccharide to glucose as main monosaccharide unit