Figures & data
Normal saline was given to control group, while diclofenac sodium 100mg/kg was given to standard group. Sample N 1 is 200 mg/kg of polyherbal n-hexane extract, sample N 2 is 400 mg/kg of polyherbal n-hexane extract, and sample N 3 is 800 mg/kg of polyherbal n-hexane extract. Each group was analyzed by using two-way ANOVA followed by Tukey’s test. When control and standard group are compared with sample groups, results are considered nonsignificant (ns) if p > 0.05; first bar denoted by (*) indicates the compared significance of control with standard and extracts and 2nd bar denoted by (#) indicates the comparison of standard group (diclofenac sodium) with sample group. Results are significant (*, #) if p < 0.05, more significant (**, ##) if p < 0.01, very significant (***, ###) if p < 0.001, and highly significant (****, ####) if p < 0.0001.
Normal saline was given to control group while diclofenac sodium 100mg/kg was given to standard group. Sample M 1 is 200 mg/kg of polyherbal methanolic extract, sample M 2 is 400 mg/kg of polyherbal methanolic extract, and sample M 3 is 800 mg/kg of polyherbal methanolic extract. Each group is analyzed by using ANOVA followed by Tukey’s test. When control group and standard group compared with sample groups, results are considered nonsignificant (ns) if p > 0.05; first bar denoted by (*) indicates the compared significance of control with sample groups and 2nd bar denoted by (#) indicates the compared significance of standard group (diclofenac sodium) with sample group. Results are significant (*, #) if p < 0.05, more significant (**, ##) if p < 0.01, very significant (***, ###) if p < 0.001, and highly significant (****, ####) if p < 0.0001.
Normal saline was given to control group while diclofenac sodium 100mg/kg was given to standard group. Sample NG 1% is hydrogel formulation containing 1.0 g of polyherbal n-hexane extract, Sample NG 3% is hydrogel formulation containing 3.0 g of polyherbal n-hexane extract and sample NG 5% is hydrogel formulation containing 5.0 g of polyherbal n-hexane extract. Each group is analyzed by using ANOVA followed by Tukey’s test. When control group and standard group compared with sample groups, results are considered nonsignificant (ns) if p > 0.05; first bar denoted by (*) indicates the compared significance of control with sample groups and 2nd bar denoted by (#) indicates the compared significance of standard group (diclofenac sodium) with sample group. Results are significant (*, #) if p < 0.05, more significant (**, ##) if p < 0.01, very significant (***, ###) if p < 0.001, and highly significant (****, ####) if p < 0.0001.
Normal saline was given to control group while diclofenac sodium 100mg/kg was given to standard group. Sample MG 1% is hydrogel formulation containing 1.0 g of polyherbal methanolic extract, Sample MG 3% is hydrogel formulation containing 3.0 g of polyherbal methanolic extract and sample MG 5% is hydrogel formulation containing 5.0 g of polyherbal methanolic extract. Each group is analyzed by using ANOVA followed by tukey’s test. When control group and standard group compared with sample groups, results are considered nonsignificant (ns) if p > 0.05; first bar denoted by (*) indicates the compared significance of control with sample groups and 2nd bar denoted by (#) indicates the compared significance of standard group (diclofenac sodium) with sample group. Results are significant (*, #) if p < 0.05, more significant (**, ##) if p < 0.01, very significant (***, ###) if p < 0.001, and highly significant (****, ####) if p < 0.0001.
Normal saline was given to control group while diclofenac sodium 100mg/kg was given to standard group. Sample N 1 is 200 mg/kg of polyherbal n-hexane extract, sample N 2 is 400 mg/kg of polyherbal n-hexane extract and sample N 3 is 800 mg/kg of polyherbal n-hexane extract. Each group is analyzed by using ANOVA followed by tukey’s test. When control group and standard group compared with sample groups, results are considered nonsignificant (ns) if p > 0.05; first bar denoted by (*) indicates the compared significance of control with sample groups and 2nd bar denoted by (#) indicates the compared significance of standard group (diclofenac sodium) with sample group. Results are significant (*, #) if p < 0.05, more significant (**, ##) if p < 0.01, very significant (***, ###) if p < 0.001, and highly significant (****, ####) if p < 0.0001.
Normal saline was given to control group while diclofenac sodium 100mg/kg was given to standard group. Sample M 1 is 200 mg/kg of polyherbal methanolic extract, sample M 2 is 400 mg/kg of polyherbal methanolic extract and sample M 3 is 800 mg/kg of polyherbal methanolic extract. Each group is analyzed by using ANOVA followed by tukey’s test. When control group and standard group compared with sample groups, results are considered nonsignificant (ns) if p > 0.05; first bar denoted by (*) indicates the compared significance of control with sample groups and 2nd bar denoted by (#) indicates the compared significance of standard group (diclofenac sodium) with sample group. Results are significant (*, #) if p < 0.05, more significant (**, ##) if p < 0.01, very significant (***, ###) if p < 0.001, and highly significant (****, ####) if p < 0.0001.
Normal saline was given to control group while diclofenac sodium 100mg/kg was given to standard group. Sample NG 1% is hydrogel formulation containing 1.0 g of polyherbal n-hexane extract, Sample NG 3% is hydrogel formulation containing 3.0 g of polyherbal n-hexane extract and sample NG 5% is hydrogel formulation containing 5.0 g of polyherbal n-hexane extract. Each group is analyzed by using ANOVA followed by tukey’s test. When control group and standard group compared with sample groups, results are considered nonsignificant (ns) if p > 0.05; first bar denoted by (*) indicates the compared significance of control with sample groups and 2nd bar denoted by (#) indicates the compared significance of standard group (diclofenac sodium) with sample group. Results are significant (*, #) if p < 0.05, more significant (**, ##) if p < 0.01, very significant (***, ###) if p < 0.001, and highly significant (****, ####) if p < 0.0001.
Normal saline was given to control group while diclofenac sodium 100mg/kg was given to standard group. Sample MG 1% is hydrogel formulation containing 1.0 g of polyherbal methanolic extract, Sample MG 3% is hydrogel formulation containing 3.0 g of polyherbal methanolic extract and sample MG 5% is hydrogel formulation containing 5.0 g of polyherbal methanolic extract. Each group is analyzed by using ANOVA followed by tukey’s test. When control group and standard group compared with sample groups, results are considered nonsignificant (ns) if p > 0.05; first bar denoted by (*) indicates the compared significance of control with sample groups and 2nd bar denoted by (#) indicates the compared significance of standard group (diclofenac sodium) with sample group. Results are significant (*, #) if p < 0.05, more significant (**, ##) if p < 0.01, very significant (***, ###) if p < 0.001, and highly significant (****, ####) if p < 0.0001.
Normal saline was given to control group while diclofenac sodium 100mg/kg was given to standard group. Sample N 1 is 200 mg/kg of polyherbal n-hexane extract, sample N 2 is 400 mg/kg of polyherbal n-hexane extract and sample N 3 is 800 mg/kg of polyherbal n-hexane extract. Each group is analyzed by using ANOVA followed by tukey’s test. When control group and standard group compared with sample groups, results are considered nonsignificant (ns) if p > 0.05; first bar denoted by (*) indicates the compared significance of control with sample groups and 2nd bar denoted by (#) indicates the compared significance of standard group (diclofenac sodium) with sample group. Results are significant (*, #) if p < 0.05, more significant (**, ##) if p < 0.01, very significant (***, ###) if p < 0.001, and highly significant (****, ####) if p < 0.0001.
(Sample N 1 is 200 mg/kg of polyherbal n-hexane extract, sample N 2 is 400 mg/kg of polyherbal n-hexane extract and sample N 3 is 800 mg/kg of polyherbal n-hexane extract).
Normal saline was given to control group while diclofenac sodium 100mg/kg was given to standard group. Sample M 1 is 200 mg/kg of polyherbal methanolic extract, sample M 2 is 400 mg/kg of polyherbal methanolic extract and sample M 3 is 800 mg/kg of polyherbal methanolic extract. Each group is analyzed by using ANOVA followed by tukey’s test. When control group and standard group compared with sample groups, results are considered nonsignificant (ns) if p > 0.05; first bar denoted by (*) indicates the compared significance of control with sample groups and 2nd bar denoted by (#) indicates the compared significance of standard group (diclofenac sodium) with sample group. Results are significant (*, #) if p < 0.05, more significant (**, ##) if p < 0.01, very significant (***, ###) if p < 0.001, and highly significant (****, ####) if p < 0.0001.
(Sample M 1 is 200 mg/kg of polyherbal methanolic extract, sample M 2 is 400 mg/kg of polyherbal methanolic extract and sample M 3 is 800 mg/kg of polyherbal methanolic extract).
Normal saline was given to control group while diclofenac sodium 100mg/kg was given to standard group. Sample NG 1% is hydrogel formulation containing 1.0 g of polyherbal n-hexane extract, Sample NG 3% is hydrogel formulation containing 3.0 g of polyherbal n-hexane extract and sample NG 5% is hydrogel formulation containing 5.0 g of polyherbal n-hexane extract. Each group is analyzed by using ANOVA followed by tukey’s test. When control group and standard group compared with sample groups, results are considered nonsignificant (ns) if p > 0.05; first bar denoted by (*) indicates the compared significance of control with sample groups and 2nd bar denoted by (#) indicates the compared significance of standard group (diclofenac sodium) with sample group. Results are significant (*, #) if p < 0.05, more significant (**, ##) if p < 0.01, very significant (***, ###) if p < 0.001, and highly significant (****, ####) if p < 0.0001.
(Sample NG 1% is hydrogel formulation containing 1.0 g of polyherbal n-hexane extract, Sample NG 3% is hydrogel formulation containing 3.0 g of polyherbal n-hexane extract and sample NG 5% is hydrogel formulation containing 5.0 g of polyherbal n-hexane extract)
Normal saline was given to control group while diclofenac sodium 100mg/kg was given to standard group. Sample MG 1% is hydrogel formulation containing 1.0 g of polyherbal methanolic extract, Sample MG 3% is hydrogel formulation containing 3.0 g of polyherbal methanolic extract and sample MG 5% is hydrogel formulation containing 5.0 g of polyherbal methanolic extract. Each group is analyzed by using ANOVA followed by tukey’s test. When control group and standard group compared with sample groups, results are considered nonsignificant (ns) if p > 0.05; first bar denoted by (*) indicates the compared significance of control with sample groups and 2nd bar denoted by (#) indicates the compared significance of standard group (diclofenac sodium) with sample group. Results are significant (*, #) if p < 0.05, more significant (**, ##) if p < 0.01, very significant (***, ###) if p < 0.001, and highly significant (****, ####) if p < 0.0001.