Medicinal plants with anti-mutagenic potential

Figures & data

Table 1. Other medicinal plants possessing anti-mutagenic activity.

Plant	Family	Part used	Active constituents	References
Pueraria lobata	Leguminosae	Roots	Isoflavone	[26]
Syzygium aromaticum	Myrtaceae	Buds	Phenylpropanoids	[27]
Aronia melanocarpa	Rosaceae	Fruits	Anthocyanins	[28]
Kalopanax pictus	Araliaceae	Stem bark	Hederagenin monodesmosides and bisdesmosides	[29]
Pistacia lentiscus	Anacardiaceae	Leaves	Pentagalloylglucose and Gallic acid	[30]
Liquidambar orientalis Mill	Hamamelidaceae	Leaves	Phenolic compounds	[31]
Aspalathus linearis	Fabaceae	Leaves	Flavonoids	[32]
Calendula officinalis	Asteraceae	Aerial parts	Saponins	[33,34]
Carum copticum	Apiaceae	Fruit	Phenolic terpenoids	[35]
Lupinus campestris	Fabaceae	Seeds	Phenolic compounds, oligosaccharides and quinolizidinic alkaloids	[36]
Gleditsia sinensis	Leguminosae	Thorns	Triterpenoid, steroids, stigmasterol and beta sitositosterol	[37]
Scutellaria baicalensis Georgi	Lamiaceae	Roots	Flavones	[38]
Ginkgo biloba	Ginkgoaceae	Leaves	Polyphenols	[39]
Belamcanda chinensis	Iridaceae	Rhizomes	Iridin and tectoridin in the glycoside fractions and the 5,6,7,3′-tetrahydroxy-4′-methoxy isoflavone and irigenin, tectorigenin	[40]
Hamamelis virginiana	Hamamelidaceae	Bark	Proanthocyanidins	[41]
Cassia tora	Caesalpinaceae	Seeds	Anthraquinone aglycones and naphthopyrone glycosides	[42]
Salvia officinalis	Lamiaceae	leaves	Essential oil and its monoterpenes	[43]
Pistacia lentiscus	Anacardiaceae	Leaves	Pentagalloylglucose	[44]
Psychotria umbellata Vell	Rubiaceae	Leaves	Monoterpene indole alkaloid psychollatine	[45]
Caralluma adscendens Roxb	Asclepiadaceae	Flowers	Pregnane glycosides	[46]

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Ga̧Siorowski K, Szyba K, Brokos B, et al. Antimutagenic activity of anthocyanins isolated from Aronia melanocarpa fruits. Cancer Letters. 1997;119(1):37–46.

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Lee K-T, Sohn I-C, Park H-J, et al. Essential moiety for antimutagenic and cytotoxic activity of hederagenin monodesmosides and bisdesmosides isolated from the stem bark of Kalopanax pictus. Planta Med. 2000;66(04):329–332.

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Abdelwahed A, Bouhlel I, Skandrani I, et al. Study of antimutagenic and antioxidant activities of Gallic acid and 1, 2, 3, 4, 6-pentagalloylglucose from Pistacia lentiscus: confirmation by microarray expression profiling. Chem Biol Interact. 2007;165(1):1–13.

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Martínez CJ, Loarca-Piña G, Ortíz GD. Antimutagenic activity of phenolic compounds, oligosaccharides and quinolizidinic alkaloids from Lupinus campestris seeds. Food Addit Contam. 2003;20(10):940–948.

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Lim J-C, Park JH, Budesinsky M, et al. Antimutagenic constituents from the thorns of Gleditsia sinensis. Chem Pharm Bull. 2005;53(5):561–564.

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Wożniak D, E, Lamer‐Zarawska A. Matkowski Antimutagenic and antiradical properties of flavones from the roots of Scutellaria baicalensis Georgi. Nahrung. 2004;48(1):9–12.

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Wozniak D, Janda B, Kapusta I, et al. Antimutagenic and anti-oxidant activities of isoflavonoids from Belamcanda chinensis (L.) DC. Mutat Res/Genet Toxicol Environ Mutagen. 2010;696(2):148–153.

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Dauer A, Metzner P, Schimmer O. Proanthocyanidins from the bark of Hamamelis virginiana exhibit antimutagenic properties against nitroaromatic compounds. Planta Med. 1998;64(04):324–327.

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Choi J, Lee H, Park K-Y, et al. In vitro antimutagenic effects of anthraquinone aglycones and naphthopyrone glycosides from Cassia tora. Planta Med. 1997;63(01):11–14.

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Vuković-Gačić B, Nikčević S, Berić-Bjedov T, et al. Antimutagenic effect of essential oil of sage (Salvia officinalis L.) and its monoterpenes against UV-induced mutations in Escherichia coli and Saccharomyces cerevisiae. Food Chem Toxicol. 2006;44(10):1730–1738.

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Hayder N, Ben Ammar R, Abdelwahed A, et al. Antibacterial and antimutagenic activitiy of extracts and essential oil from (Tunisian) Pistacia lentiscus. Toxicol Environ Chem. 2005;87(4):567–573.

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Fragoso V, Nascimento N. C d, Moura DJ, et al. Antioxidant and antimutagenic properties of the monoterpene indole alkaloid psychollatine and the crude foliar extract of Psychotria umbellata Vell. Toxicol in Vitro. 2008;22(3):559–566.

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Gowri S, Chinnaswamy P. Evaluation of in vitro antimutagenic activity of Caralluma adscendens roxb. in bacterial reverse mutation assay. J Nat Prod Plant Resour. 2011;1(4):27–34.

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