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Autophagic Punctum

ATL3, a cargo receptor for reticulophagy

ORCID Icon, ORCID Icon & ORCID Icon
Pages 1465-1466 | Received 13 Mar 2019, Accepted 27 Mar 2019, Published online: 28 Apr 2019

Figures & data

Figure 1. Model of ATL3 in reticulophagy. To drive tubular ER turnover by reticulophagy, ATL3 specifically binds to GABARAPs via 2 GIMs, which leads to the recruitment of the phagophore, the sequestration of tubular ER within autophagosomes and the final degradation by a lysosome.

Figure 1. Model of ATL3 in reticulophagy. To drive tubular ER turnover by reticulophagy, ATL3 specifically binds to GABARAPs via 2 GIMs, which leads to the recruitment of the phagophore, the sequestration of tubular ER within autophagosomes and the final degradation by a lysosome.

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